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Table Of Contents

1.1. GENERAL INDICATIONS FOR LIVER TRANSPLANTATION
1.2.1. Acute Liver Failure
1.2.2. Primary Biliary Cirrhosis (PBC)
1.2.3. Primary Sclerosing Cholangitis (PSC)
1.2.4. Chronic Viral Hepatitis
1.2.5. Alcoholic Liver Disease
1.2.6. Hepatic Malignancy
1.3. UNCOMMON INDICATIONS FOR LIVER
1.4.1. Absolute Contraindications
1.4.2. Relative Contraindications
2.1. ORGAN MATCHING
2.2.1. Workup of Candidates
2.2.2.Waiting Lists and Waiting Period
2.3.1. Fulminant Hepatic Failure
2.3.2. Chronic Liver Disease
2.3.3. Retransplantation: Whether or Not?
3.1. INTRODUCTION
3.2.1.RefractoryAscites
3.2.2.Spontaneous Bacterial Peritonitis (SBP): Treatment
3.2.3.Spontaneous Bacterial Peritonitis: Prophylaxis
3.2.4.Hepatorenal Syndrome (HRS)
3.3.1.Treatment
3.3.2.Benefits
3.4.PRURITUS
3.5.ESOPHAGEAL VARICES
3.6.MALNUTRITION
3.7.SUMMARY
4.1.1.General Indications
4.1.2.Contraindications
4.1.3.1. Blood Work
4.1.3.2.Tests, X-Rays, and Specialty Evaluation
4.1.3.3.Specific Testing Based on Diagnosis
4.1.3.4.Tissue Typing and Organ Matching
4.1.4.Waiting Lists and Waiting Period
4.2.1.Indications and Testing
4.2.2. Simultaneous Pancreas–Kidney Transplantation (SPK)
4.2.3. Pancreas after Kidney Transplantation (PAK)
4.2.4.Pancreas Transplant Alone (PTA)
4.3.TIMING OF KIDNEY AND PANCREAS TRANSPLANTATION
5.1.1.Screening
5.1.2. Perioperative Period
5.1.3. Postoperative Period
5.2.1. Pretransplant Screening
5.2.2.Nontransplantation Candidates
5.2.3.Waiting Phase
5.2.4.Hospitalization Postsurgery
5.2.5.Discharge Planning
6.1.PRETRANSPLANT COORDINATOR’S ROLE
6.2.POSTTRANSPLANT COORDINATOR’S ROLE
7.1.1. NOTA, OPTN, and UNOS
7.1.2. Death by Neurologic Criteria
7.2.1. Donor Evaluation and Management
8.1.WHOLE LIVER PROCUREMENT
8.2.1.In situSplit-LiverProcurement
8.2.2.Living Donor Liver Procurement
8.2.3.Complications and Ethical Concerns of Living Donor LiverProcurement
9.1. CADAVERIC DONOR NEPHRECTOMY
9.2.1. Traditional Open Donor Nephrectomy
9.2.2.1. Preoperative Evaluation
9.2.2.2. Surgical Technique
9.2.2.3. Results
9.2.3. Complications and Ethics of Living Donor Kidney Procurement
9.3.1. Pancreas without Liver Procurement
9.3.2. Pancreas with Liver Procurement
9.4. LIVING DONOR PANCREATECTOMY
10.1. INTRODUCTION
10.2.1.1.Hepatectomy and Bypass
10.2.1.2.Anhepatic Phase and Donor Liver Implantation
10.2.1.3.The Problem of Portal Vein Thrombosis
10.2.2.Piggyback Techniques
10.3.Heterotopic/Auxiliary Transplantation
10.4.1.Reduced-Size Liver Transplantation
10.4.2.1. Anatomical Considerations
10.4.2.2.Surgical Technique
10.4.2.3.Left Lateral Segment Splitting (ex situ)
10.4.2.4.Donor Selection Criteria for Split-Liver
10.4.2.5.Recipient Selection Criteria
10.4.3.Living Donor Liver Transplantation
10.4.4.Recipient Operation for Split-Liver and Living Donor Grafts
10.4.5.Special Considerations in Pediatric Liver Transplantation
11.1.BACKTABLE GRAFT PREPARATION
11.2.1. Position and Preparation
11.2.2. Incision at Lower Quadrant of Abdomen
11.2.3. Retroperitoneal Space Dissection
12.1.BACKTABLE PREPARATION
12.2.IMPLANTATION PROCEDURE
13.1. ANESTHETIC MANAGEMENT OF THE ORGAN DONOR
13.2.1.1. Cardiovascular System
13.2.1.2. Pulmonary System
13.2.1.3. Hepatorenal Syndrome
13.2.1.4. Metabolic System
13.2.1.5.Neurologic System
13.2.1.6. Coagulation
13.2.2.1. General Measures
13.2.2.2. Hemodynamics, Lines, and Venovenous Bypass
13.2.2.3. Antibiotics, Immunosuppression, and Cytoprotection
13.2.2.4. Temperature Management
13.2.3. Intraoperative Management
13.3. MANAGEMENT OF THE KIDNEY TRANSPLANT
13.4. MANAGEMENT OF THE PANCREAS TRANSPLANT RECIPIENT
14.1.GENERAL INTENSIVE CARE ISSUES
14.2.RENAL DYSFUNCTION
14.3. NEUROLOGIC ISSUES
14.4. CARDIOVASCULAR ISSUES
14.5.HEMATOLOGIC ALTERATIONS
14.6.INFECTIONS IN THE IMMEDIATE POSTOPERATIVE PERIOD
14.7.PRIMARY GRAFT NONFUNCTION (PNF)
14.8. HEMORRHAGIC NECROSIS
14.9. INDUCTION IMMUNOSUPPRESSION
14.10.HEPATIC ARTERY
14.11.PORTAL VEIN
14.12.INFERIOR VENA CAVA (IVC) AND HEPATIC VEINS
14.13.BILIARY SYSTEM
14.14.REJECTION
14.15.INTRA-ABDOMINAL BLEEDING
15.1. IMMUNOSUPPRESSION
15.2. FLUID MANAGEMENT
15.3.HEMODIALYSIS
15.4.HYPER- AND HYPOTENSION
15.5.HYPERGLYCEMIA
15.6.FOLEY CATHETER MANAGEMENT
15.7.VIRAL PROPHYLAXIS
15.8.SURGICAL COMPLICATIONS
15.9.COMPLICATIONS MANIFESTING IN ALLOGRAFT DYSFUNCTION
15.10.VASCULAR COMPLICATIONS
16.2.2.2. Venous Graft Thrombosis
16.2.3.1. Graft Pancreatitis
16.2.3.2. Intra-Abdominal Abscesses
16.2.3.3. Intrapancreatic Abscesses
16.2.3.4. Pancreatocutaneous Fistula
16.2.3.5. Rejection
16.2.3.6. Hemorrhage
17.1. INTRODUCTION
17.2. GLUCOCORTICOIDS
17.3.1. Cyclosporine A (CyA)
17.3.2.Tacrolimus (FK506, Prograf®
17.4.1. Azathioprine (Imuran®
17.4.2. Mycophenolate Mofetil (Cellcept®
17.5.1. Muromonab-CD3 (Orthoclone OKT3)
17.5.2. Antithymocyte Globulins (ATGs)
17.5.3. Interleukin 2 (IL-2) Receptor Antagonists
17.6. SIROLIMUS (RAPAMUNE®)
17.7. IMMUNOSUPPRESSIVE REGIMENS
17.8.1. Antivirals
17.8.2. Antibacterials
17.8.3. Antifungals
17.8.4. Antihypertensives
17.8.5. Hypoglycemic Agents
17.8.6. Lipid-Lowering Agents
17.8.7. Supplements
18.1.1. Renal Dysfunction
18.1.2. Hypertension
18.1.3. Diabetes Mellitus
18.1.4. Hyperlipidemia
18.1.5.Obesity
18.1.6.Osteoporosis
18.1.7.1. Posttransplant Lymphoproliferative Disease
18.1.7.2. Skin Cancer and Kaposi's Sarcoma
18.2.1.Disease Recurrence
18.2.2.Chronic Rejection
18.2.3.Technical Problems
19.2.1.1. Lymphocele
19.2.1.2. Ureteric Stenosis
19.2.1.3. Renal Artery Stenosis
19.2.2. Chronic Rejection
19.2.3. Disease Recurrence
19.3.1. Rejection
19.3.2.1. Hematuria
19.3.2.2.Duodenal–Bladder Leaks
19.3.2.3. Urethral Strictures
19.3.2.4. Chronic Urinary Tract Infections (UTIs)
19.3.2.5. Metabolic Complications
19.3.2.6. Reflux Pancreatitis
19.3.2.7. Bladder Mucosal Neoplasia
19.3.3. Other Complications
20.1.1.Overall Survival
20.1.2.1b.Severity of Liver Disease.More important than the particular
20.1.2.2c. Obesity.Patients with chronic liver disease and malnutrition
20.1.2.3.Postoperative Risk Factors
20.1.3.Quality of Life
20.1.4.Pregnancy after Liver Transplantation
20.2.KIDNEY TRANSPLANTATION
20.3.1.Graft Loss and Immunosuppression
20.3.2.Survival Rates and Results
21.1.LIVER TRANSPLANT
21.2.1.Organ Selection
21.2.2.1. Hyperacute Rejection
21.2.2.2.Acute Humoral Rejection
21.2.2.3.Acute Vascular Rejection
21.2.2.4c.Differential Diagnosis for Acute Cellular Rejection.CyA
21.2.2.5. Chronic Rejection
21.2.3.Scoring Rejection
21.2.4.Immunosuppressive Drug Toxicity
21.2.5.Posttransplantation Lymphoproliferative Disorders
21.2.6.1. Ischemic Injury
21.2.6.2. Viral Infections
21.2.6.3.De Novo Glomerulonephritis
21.2.6.4.Other De Novo Glomerulopathies
21.2.6.5.Recurrent Diseases
22.1.1.1. Duplex Ultrasound
22.1.1.2. Computed Tomography
22.1.1.3. Magnetic Resonance
22.1.1.4. Conventional Angiography
22.1.1.5. Scintigraphy
22.1.2.1. Duplex Ultrasound
22.1.2.2.Computed Tomography
22.1.2.3.Magnetic Resonance
22.1.2.4. Conventional Angiography
22.2.1.1. Vascular
22.2.1.2. Biliary
22.2.1.3. Rejection
22.2.2.1. Vascular
22.2.2.2. Nonvascular
22.2.3.1. Vascular Thrombosis
22.2.3.2. Rejection
22.2.3.3. Bladder Leak
22.2.3.4. Perigraft Collections
23,200–201
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Transplantation - Practical Manual of Abdominal Organ Transplantation - 2002

Transplantation - Practical Manual of Abdominal Organ Transplantation - 2002

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Published by: basyony1970 on Feb 29, 2012
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