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Aplastic Anemia Pa Tho Physiology

Aplastic Anemia Pa Tho Physiology

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Published by neil0522

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Published by: neil0522 on Nov 24, 2008
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07/12/2013

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Pathophysiology
- fatigue- dizziness- shortnessof breath- pale skin- bruising- oral thrushPredisposing Factors:
Precipitating Factors:
Damage to the microenvironmentof the marrowAltered bone marrow functionReduced hematopoiesis
APLASTICANEMIA
AnemiaLeukopeniaThrombocytopenia
 
If Treated:Medical management
Blood transfusion-Pack RBC-Platelet concentrate
Bone MarrowTransplantation (BMT)
Peripheral Blood StemCell Transplantation(PBSCT)
Immunosuppressive Therapy
Antithymocyte Globulin
Cyclosporine
Supportive theraphy
IVF Therapy
Drug Theraphy
If Not Treated:
Pancytopenia relapseRBC platelet WBCHypoxemia hemorrhage localized infectionHypoxia hypovolemic systemic infectionShock Anoxia septic shock 
DEATH

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