Description

This 4-part project examines the National Institute for Health and Clinical Excellence (NICE) and its operations, and the implications for comparative effectiveness reviews in the U.S.Part 1 entails a non-technical overview of NICE, encompassing its governance and organization, topic selection procedures, evidence requirements and assessment methods, and guidance dissemination and implementation. Part 2 provides an in-depth investigation of evidence requirements and assessment methods. Part 3 involves an analysis of public comments on NICE submitted to the House of Commons Health Select Committee, focusing on key stakeholder perspectives on the appraisal process and broader NICE operations.Part 4 examines NICE procedures and standards in the context of the U.S. landscape, and identifies those factors or forces unique to the U.S. marketplace, in comparison to the U.K. and other EU Member States, where applicable.