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Azithromycin (Zithromycin)

Azithromycin (Zithromycin)

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Published by Adrianne Bazo

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Published by: Adrianne Bazo on Dec 05, 2008
Copyright:Attribution Non-commercial

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05/14/2012

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Adrianne Bazo11-18-08
Clinical Medications WorksheetsGeneric Name
azithromycin
Trade Name
Zithromax
Classification
agents for atypicalmycobacterium, anti-infectives
Dose
500mg
Route
PO
Time/frequency
Q day for four or moredays
Peak 
2.5-3.2 hrs
Onset
rapid
Duration
24 hr 
Normal dosage range
Acute bacterial sinusitis
--
500 mg once daily for 3 days or single 2 gdose of extended-release suspension (Zmax)
Why is your patient getting this medication
Extended-release suspension (ZMax)Acute bacterialsinusitis and community-acquired pneumonia in adults
For IV meds, compatibility with IV drips and/orsolutions
 NA
Mechanism of action and indications
(Why med ordered)
Inhibits protein synthesis at the level of the 50S bacterial ribosome
Nursing Implications (what to focus on)
Contraindications/warnings/interactions
Hypersensitivity to azithromycin, erythromycin, or other macrolideanti-infectivesZmax extended release oral suspension is not bioequivalent or interchangeable with azithromycin oral suspension
Common side effects
Abdominal pain, diarrhea, nausea
Interactions with other patient drugs, OTC orherbal medicines
(ask patient specifically)
none
Lab value alterations caused by medicine
May cause ↑ serum bilirubin, AST, ALT, LDH, and alkaline phosphatase concentrations. May cause ↑ creatine phosphokinase, potassium, prothrombin time, BUN, serum creatinine, and bloodglucose concentrations. May occasionally cause ↓ WBC and plateletcount
Be sure to teach the patient the following about thismedication
Instruct patients to take medication as directed and to finish the drugcompletely, even if they are feeling better. Tell patient to take misseddoses as soon as possible unless almost time for next dose; do notdouble doses. Advise patients that sharing of this medication may bedangerous
Nursing Process- Assessment
(Pre-administration assessment)
Assess patient for infection (vital signs;appearance of wound, sputum, urine, and stool;WBC) at beginning of and throughout therapy.Obtain specimens for culture and sensitivity beforeinitiating therapy. First dose may be given beforereceiving results
Assessment
Why would you hold or not give thismed?
Observe for signs and symptoms of anaphylaxis (rash, pruritus, laryngeal edema,wheezing). Notify the physician or other health care professional immediately if theseoccur chest pain, palpitations, yellowing of skin or eyes, or signs of superinfection (black, furryovergrowth on the tongue; vaginal itching or discharge; loose or foul-smelling stools). if fever and diarrhea develop, especially if stoolcontains blood, pus, or mucus
Evaluation
Check after giving 
Resolution of the signs andsymptoms of infection. Length of time for complete resolutiondepends on the organism and siteof infection

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