NURS 2516 Clinical Medications Worksheets
(You will need to make additional copies of these forms)Generic NameclonazepamTrade NameKlonopinClassificationanticonvulsantsDose1mgRouteIVTime/frequency0900, 2100; twice dailyPeak 1-2 hr Onset20-60 minDuration6-12 hr For IV meds, compatibility with IV drips and /or solutions N/AMechanism of action and indications(Why med ordered)Anticonvulsant effects may be due to presynapticinhibitionProduces sedative effects in the CNS, probably bystimulating inhibitory GABA receptors. Muscle spasms,associated anxiety.
Nursing Implications (what to focus on)
Contraindications/warnings/interactionsHypersensitivity to clonazepam or other benzodiazepines• Severe liver disease
Use Cautiously in:
• Narrow-angle glaucoma• Chronic respiratory disease• History of porphyria• Do not discontinue abruptlyCommon side effectsBehavioral side effects, drowsiness, ataxiaInteractions with other patient drugs, OTC or herbalmedicines (ask patient specifically)Alcohol, antidepressants , antihistamines ,otherbenzodiazepines, and opioid analgesics --concurrentuse results in ↑ CNS depressionLab value alterations caused by medicinePatients on prolonged therapy should have CBC and liver function test results evaluated periodically. May cause an ↑in serum bilirubin, AST, and ALT○ May cause ↓ thyroidal uptake of sodium iodide,
IBe sure to teach the patient the following about thismedicationInstruct patient to take medication exactly as directed. Takemissed doses within 1 hr or omit; do not double doses.Abrupt withdrawal of clonazepam may cause statusepilepticus, tremors, nausea, vomiting, and abdominal andmuscle cramps• Medication may cause drowsiness or dizziness. Advise patient to avoid driving or other activities requiringalertness until response to drug is known• Caution patient to avoid taking alcohol or other CNSdepressants concurrently with this medication• Advise patient to notify health care professional of medication regimen prior to treatment or surgery• Instruct patient and family to notify health care professional of unusual tiredness, bleeding, sore throat,fever, clay-colored stools, yellowing of skin, or