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Naloxone (Narcan)

Naloxone (Narcan)

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Published by Adrianne Bazo

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Published by: Adrianne Bazo on Dec 06, 2008
Copyright:Attribution Non-commercial

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08/10/2013

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NURS 1566 Clinical Form 3: Clinical Medications Worksheets
(You will need to make additional copies of these forms)
Generic Name
 Naloxone
Trade Name
 Narcan
Classification
Antidotes (for opioids)
Dose
0.2
Route
IVP
Time/frequency
PRN
Peak 
Unknown
Onset
1-2 min
Duration
45 min
Normal dosage range
0.02-0.2 mg q 2-3 min until response obtained; repeat q 1-2hr if needed
Why is your patient getting this medication
Reversal of CNS depression and respiratorydepression because of suspected opioid overdosage
For IV meds, compatibility with IV drips and/orsolutions
Administer undiluted for 
suspected opioid overdose
For patients with
opioid-induced respiratory depression,
dilute 0.4mg of naloxone in 10 ml of sterile water or 0.9% NaCl for injection
.
Rate:
Administer at a rate of 0.1-0.4 mg over 15seconds in patients with
suspected opioid overdose
Mechanism of action and indications
(Why med ordered)
Competitively blocks the effects of opioids, includingCNS and respiratory depression, without producing anyagonist (opioid-like) effectsReversal of signs of opioid excess
Nursing Implications (what to focus on)
Contraindications/warnings/interactions
Hypersensitivity
Resuscitation equipment, oxygen, vasopressors, andmechanical ventilation should be available to supplementnaloxone therapy as needed
Common side effects
none
Interactions with other patient drugs, OTC orherbal medicines
(ask patient specifically)
 None for this pt
Lab value alterations caused by medicine
none
Be sure to teach the patient the following about thismedication
As medication becomes effective, explain purpose andeffects of naloxone to patient
Nursing Process- Assessment
(Pre-administration assessment)
Monitor respiratory rate, rhythm, and depth;pulse, ECG, blood pressure; and level of consciousness frequently for 3-4 hr after theexpected peak of blood concentrations.After a moderate overdose of a short half-life opioid, physical stimulation may beenough to prevent significanthypoventilation. The effects of some opioidsmay last longer than the effects of naloxone, and repeat doses may benecessaryAssess patient for level of pain after administration when used to treatpostoperative respiratory depression.Naloxone decreases respiratory depressionbut also reverses analgesia
Assessment
Why would you hold or not give thismed?
Only give for suspected opioidoverdose/toxicity
Evaluation
Check after giving 
Alertness without significantpain or withdrawalsymptoms

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