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Group I - Carbohydrate Metabolism

Group I - Carbohydrate Metabolism

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Published by iqbal tambunan
Matthew P. Harber, Simon Schenk, Ariel L. Barkan and Jeffrey F. Horowitz
Am J Physiol Endocrinol Metab 289:306-312, 2005. First published Mar 29, 2005; doi:10.1152/ajpendo.00069.2005 You might find this additional information useful... This article cites 29 articles, 15 of which you can access free at: http://ajpendo.physiology.org/cgi/content/full/289/2/E306#BIBL This article has been cited by 1 other HighWire hosted article: Low-carbohydrate nutrition and metabolism E. C Westman, R. D Feinman,
Matthew P. Harber, Simon Schenk, Ariel L. Barkan and Jeffrey F. Horowitz
Am J Physiol Endocrinol Metab 289:306-312, 2005. First published Mar 29, 2005; doi:10.1152/ajpendo.00069.2005 You might find this additional information useful... This article cites 29 articles, 15 of which you can access free at: http://ajpendo.physiology.org/cgi/content/full/289/2/E306#BIBL This article has been cited by 1 other HighWire hosted article: Low-carbohydrate nutrition and metabolism E. C Westman, R. D Feinman,

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Categories:Types, Research, Science
Published by: iqbal tambunan on Apr 04, 2012
Copyright:Attribution Non-commercial

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08/26/2013

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doi:10.1152/ajpendo.00069.2005289:306-312, 2005. First published Mar 29, 2005;
 Am J Physiol Endocrinol Metab
Matthew P. Harber, Simon Schenk, Ariel L. Barkan and Jeffrey F. Horowitz
You might find this additional information useful...
29 articles, 15 of which you can access free at:This article citeshttp://ajpendo.physiology.org/cgi/content/full/289/2/E306#BIBL1 other HighWire hosted article:This article has been cited by[PDF] [Full Text] [Abstract] , August 1,2007; 86(2): 276-284.
Yancy and S. D PhinneyE. C Westman, R. D Feinman, J. C Mavropoulos, M. C Vernon, J. S Volek, J. A Wortman, W. S 
Low-carbohydrate nutrition and metabolism
including high-resolution figures, can be found at:Updated information and serviceshttp://ajpendo.physiology.org/cgi/content/full/289/2/E306can be found at:
 AJP - Endocrinology and Metabolism
aboutAdditional material and informationhttp://www.the-aps.org/publications/ajpendoThis information is current as of April 13, 2010 .
http://www.the-aps.org/.20814-3991. Copyright© 2005 by the American Physiological Society. ISSN: 0193-1849, ESSN: 1522-1555. Visit our website atorganization. It is published 12 times a year (monthly) by the American Physiological Society, 9650 Rockville Pike, Bethesda MDpublishes results of original studies about endocrine and metabolic systems on any level of 
 AJP - Endocrinology and Metabolism
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can exert aprofound influence on lipid and carbohydrate metabolism.More specifically, dietary carbohydrate restriction presents achallenge in maintaining systemic glucose availability becauseof the limited carbohydrate storage capacity in the humanbody. Despite the well-known sensitivity of the human body tocarbohydrate availability, the metabolic influence of dietarycarbohydrate restriction is not well understood. It has beenpostulated that a reduction in carbohydrate availability primar-ily mediates the metabolic responses to fasting (15), indicatingthat low carbohydrate availability may be a stronger metabolicregulator than a negative energy balance per se. However, littleis known about the metabolic effects of carbohydrate restric-tion without the confounding influence of weight loss ornegative energy balance.Carbohydrate restriction has been found to elicit an adaptiveincrease in fat oxidation within about 7 days (27). This adap-tation in fat oxidation may help delay the development of hypoglycemia when carbohydrate availability is very low byreducing the reliance on glucose for energy. However, bloodglucose concentration is determined by the balance betweenglucose uptake and glucose production, and unfortunately, theeffect of carbohydrate restriction on endogenous glucose pro-duction is poorly understood. Previous studies examining theinfluence of eucaloric dietary carbohydrate restriction on en-dogenous glucose availability have produced equivocal find-ings. For example, Koutsari and Sidossis (16) found that 14days of a weight-maintaining, low-carbohydrate diet did notalter endogenous glucose production, whereas Bisschop et al.(2) reported that endogenous glucose production was reduced
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