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Statement to IOM-CIRM Panel by California Stem Cell Report April 10, 2012

Statement to IOM-CIRM Panel by California Stem Cell Report April 10, 2012

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Published by DavidJensen

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Categories:Types, Research, Science
Published by: DavidJensen on Apr 10, 2012
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04/11/2012

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Machejvkha ]pgl Mgcc Vg~jvp
^wfch}bgv*G`hpjv# @auh` Dgk}gkmachejvkha}pglmgccvg~jvp+fcjo}~jp+mjl`dgk}gkNmachejvkha}pglmgccvg~jvp+mjl]papglgkp pj HJL,MHVL vguhg ~akgc A~vhc 8# 6>16Ca`hg} ak` ogkpcglgk4H ehv}p uh}hpg` pbg Machejvkha }pgl mgcc aogkmx jeehmg} hk gavcx 6>>7+ Pbgx gvg pbgk hk pgl~jvavxqwavpgv} hk Glgvxuhccg jk pbg ga}p }h`g je ]ak Evakmh}mj Fax+ Mjl~wpgv} hk mav`fjav` mavpjk} }pjj` jkpbg ecjjv }phcc wkj~gkg`+ Pbg phkx }pgl mgcc fak` a} vg}pchko hpb }wmb h}}wg} a} ~axvjcc ~vjmg}}hko# ~bjkg }gvuhmg ak` jeehmg ewvkhpwvg+ Ap pbg phlg ak` pj bgv mvg`hp# pbg pj~ }mhgkph}p ap pbg aogkmx a}vga`hko a fw}hkg}} lakaoglgkp fjji fx pbg ealjw} ejvlgv MGJ je Ogkgvac Gcgmpvhm# Dami _gcmb+ ]bgvgmjokhtg` pbap pbg Machejvkha/} ecg`ochko }pgl mgcc ugkpwvg a} hk lakx ax} ljvg aihk pj a ea}p,ljuhko }pavpw~ fw}hkg}} pbak ak ama`glhm vg}gavmb geejvp+Pj`ax# }gugk xgav} capgv# pbap h} gugk ljvg pbg ma}g+Xg}# pbg aogkmx ba} lapwvg`+ Hp kj ba} ljvg pbak a `jtgk gl~cjxgg}# acpbjwob jkg mjwc` avowg hpvglahk} pbhkcx }paeeg`+ Hp ba} bak`g` jwp $1+= fhcchjk hk ovakp} ak` cjak}+ Fwp hp h} }phcc cjjihko ejv pbg ~axjee ~vjlh}g` pj Machejvkha ujpgv} hk 6>>0+ Pbg phlg evalg ejv amphjk h} }bjvp+ Pbg MachejvkhaHk}phpwpg ejv Vgogkgvaphug Lg`hmhkg hcc vwk jwp je ma}b ejv kg ovakp} hk pbg kgrp ejwv jv ehug xgav}+ Hp}ewpwvg h} wkmgvpahk# a} a bga`chkg hk pbg djwvkac Kapwvg vgmgkpcx ~jhkpg` jwp+Lwmb mak fg }ah` afjwp pbg aogkmx/} ~a}p ak` pbg hl~amp je ^vj~j}hphjk ?1# pbg faccjp lga}wvg pbapmvgapg` MHVL+ Pbgvg h} kj `jwfp pbap pbg geejvp ba} a``g` pj }mhgkmg# bgc~g` pj lahkpahk }w~~jvp ejv }pgl mgcc vg}gavmb gugk fgxjk` Machejvkha ak` mjkpvhfwpg` }jlgbap pj Machejvkha/} gmjkjlx+ Pbgaogkmx ac}j ba} ba` hp} }bavg je `heehmwcphg}+ Hk`gg`# ^vj~j}hphjk ?1 h} fjpb a mwv}g ak` a fcg}}hko ejv MHVL+ Hp} 1>#>>> jv`} ” }jlg je bhmb `gac hpb lakaoglgkp lhkwpha ” avg uhvpwaccx hl~j}}hfcg pjmbakog# cjmig` hkpj }papg ca ak` pbg }papg mjk}phpwphjk+ Pbg lga}wvg mvgapg` ak grmg}}hugcx cavogojugvkhko fjav`# }gp w~ a pvjwfcg}jlg `wac grgmwphug avvakoglgkp ak` mvgapg` a mjkechmp je hkpgvg}p}hpwaphjk pbap ba} }ggk kgavcx acc je MHVL/} ma}b oj pj hk}phpwphjk} pbap avg vg~vg}gkpg` jk hp} ojugvkhko fjav`+Pbg}g h}}wg} avg jvpbx je }jlg gralhkaphjk fx pbg Hk}phpwpg je Lg`hmhkg ~akgc+ @gachko hpb pbglgeegmphugcx jugv pbg kgrp eg xgav} h} hl~jvpakp+ Pbg bav` vgachpx# bjgugv# h} pbap chppcg mak fg `jkg pjacpgv pbgl+ Kj jkg h} ojhko pj mbakog pbg }htg jv mjl~j}hphjk je pbg fjav` hk pbg kgrp eg xgav} jv acpgv pbg `wac grgmwphug avvakoglgkp jv mbakog pbg jpbgv ^vj~j}hphjk ?1 vgqwhvglgkp} pbap baug bal~gvg`pbg aogkmx+ Pj `j }j jwc` vgqwhvg jugvmjlhko jpbgv ~vjuh}hjk} je ^vj~j}hphjk ?1 pbap vgqwhvg }w~gv#}w~gv ladjvhpx ujpg} hk pbg cgoh}capwvg pj mbakog pbg ca jv vwkkhko akjpbgv faccjp mal~ahok hpb hp}a}}jmhapg` pgk} je lhcchjk} je `jccav} hk mj}p}+Pbg fg}p mjwv}g ap pbh} phlg jwc` }ggl pj fg pj jvi avjwk` pbg `heehmwcphg} ak` ejmw} hkpgk}gcx jkbap kgg`} pj fg `jkg jugv pbg kgrp pj pj pbvgg xgav}+ Acvga`x pbg 68 `hvgmpjv} je pbg MachejvkhaHk}phpwpg je Vgogkgvaphug Lg`hmhkg avg bgauhcx gkoaog` hk a}}g}}hko mbakog} pbap mjwc` vg`hvgmpbwk`vg`} je lhcchjk} je `jccav} a} pbg aogkmx ljug} hk ~gvba~} kg `hvgmphjk}+ Amphjk h} gr~gmpg` fxpbg ojugvkhko fjav` fx pbg gk` je kgrp ljkpb+ Pbg HJL }bjwc` mjk}h`gv jeegvhko }jlg hkpgvhl
 
owh`akmg# ohugk pbap hp} ewcc vg~jvp h} kjp gr~gmpg` wkphc Kjuglfgv+Wk`gvcxhko pbg `hvgmpjv}/ `gchfgvaphjk} avg fhcchjk,`jccav qwg}phjk} afjwp pbg mjkphkwg` grh}pgkmg je pbgaogkmx+ Mak hp }wmmg}}ewccx }ggi akjpbgv lwcphfhcchjk `jccav fjk` lga}wvg hk bap h} ak grpvglgcx bav}b ~jchphmac gkuhvjklgkp ejv }~gk`hko hk Machejvkha: Mak hp akocg jpbgv px~g} je ehkakmhko# }wmb a}ugkpwvg ~bhcakpbvj~x# ak` ~wp pjogpbgv a kjk~vjehp pbap jwc` gk}wvg pbap MHVL vg}gavmb h} kjpjv~bakg`: Pbg }wmmg}} je ghpbgv je pbg}g geejvp} `g~gk`} ovgapcx jk bgpbgv pbg }pgl mgcc aogkmx mak}bj mjkmvgpg guh`gkmg je ~jpgkphac mwvg} pbap hcc vg}jkapg hpb ghpbgv ~j}}hfcg `jkjv} jv pbgMachejvkha ~wfchm+A} H }ah`# pbg phlg h} }bjvp ” ampwaccx }bjvpgv pbak pbg ehug xgav} pbap MHVL ba} cgep pj laig ovakp}+Phlhko je fjk` lga}wvg} h} grpvglgcx hl~jvpakp+ Pj fg }wmmg}}ewc# pbgx avg lj}pcx ~vg}gkpg` pj ujpgv}hk ogkgvac gcgmphjk xgav} fgmaw}g a cavog ujpgv pwvkjwp h} hl~jvpakp hk hkkhko a~~vjuac+ Pbj}g kgrp pjjmma}hjk} mjlg hk 6>10 ak` 6>15+ Kghpbgv je pbj}g xgav} h} eaujvafcg pj MHVL+ Pbg ehv}p ” 6>10 ” accj} jkcx pj xgav} evjl pj`ax pj ~vj`wmg }pgl mgcc vg}gavmb vg}wcp} pbap avg ~gv}wa}hug pj pbg ~wfchm+ Ammjv`hko pj gmjkjlh}p}# bjgugv#Machejvkha hcc fg }phcc accjhko hk }gugvg ehkakmhac `heehmwcphg} pbap hcc laig ujpgv} phobp,eh}pg`+ Pbgkgrp gcgmphjk `apg ” 6>15 ” h} eav pjj mcj}g pj pbg gk` je fjk` ewk`hko+ _ahphko pbap cjko hcc mvgapggugk ljvg wkmgvpahkpx afjwp pbg aogkmx ak` hp} ewk`hko vgchafhchpx+ Pbap }jvp je `gcax mjwc` ac}j cga` pja fvahk `vahk ap MHVL a} gl~cjxgg} fgohk ,,, qwhpg cgohphlapgcx ” pj cjji aepgv pbghv jk ewpwvg}+Ljkgx h} }bjvp a} gcc+ MHVL ba} }jlgpbhko chig $2>> lhcchjk cgep pj bak` jwp+ Pbap }jwk`} chig a cjp#ak` hp h} a cjp+ Fwp bgk pbg aogkmx h} jeegvhko $6>> lhcchjk vjwk`} je ovakp}# hp jk/p oj eav+]j hp h} hl~gvaphug pbap MHVL ejmw} jk bap hp akp} pj baug ba~~gk+A} `hvgmpjv} vg}pcg hpb ~vhjvhphg} pbh} }~vhko# hp }ggl} pj lg pbap pbgx baug pbvgg fa}hm mbjhmg}+
Pbgx mak pvx pj `j a chppcg je gugvxpbhko# bhmb jwc` fg pbg ga}hg}p mjwv}g ak` ~vjfafcx }aph}exlakx vg}gavmbgv} ak` jpbgv}+
Pbgx mak fami aax evjl pbghv ~w}b pjav`} pbg mchkhm ak` paig pbg ~j}hphjk pbap pbg aogkmxakp} pj cax pbg fg}p ~j}}hfcg ejwk`aphjk ejv ewpwvg vg}gavmb# gugk he hp `jg} kjp bjc` ~vjlh}g je  ~vj`wmhko }jlgpbhko pbap pbg ~wfchm jwc` ga}hcx wk`gv}pak`+
Jv pbg `hvgmpjv} mak glfvamg bap }jlg hk fw}hkg}} macc a FBAO ” a fho# bahvx# aw`amhjw} ojac ” ak` `vhug }hkocg,lhk`g`cx pjav`} ~vj`wmhko }jlgpbhko pbap hcc vg}jkapg a} a mwvg jv a} a}hokhehmakp# lgakhkoewc }pg~ pj a pbgva~x+ Kjkg je pbg}g mbjhmg} jeegv} a mcgav ~apb pj }wmmg}} jv ~wfchm a~~vjuac+ @hvgmpjv} jwc` baug pj fg}aph}ehg` hpb }axhko pbap pbgx oaug hp pbghv fg}p geejvp# gugk he }~gk`hko $5 fhcchjk je par~axgv ewk`}"hkmcw`hko hkpgvg}p( `h` kjp ~vj`wmg pbg mwvg} ~vjlh}g` fx pbg }pgl mgcc mal~ahok je 6>>0+He H gvg laihko pbg mbjhmg# H jwc` }ax oj ejv pbg mwvg jv# ljvg vgach}phmaccx }papg`# oj ejv a ladjv ak`}hokhehmakp }pg~ pjav`} a mwvg+ Jkg pbap pbg ~wfchm mak wk`gv}pak`+ Hp lax gcc fg pbg vh}ihg}p je pbgpbvgg mbjhmg}+ Fwp he MHVL }paee mak }ax pj`ax pbap pbgvg h} }jch` guh`gkmg ejv gr~gmphko ojj` vg}wcp} hkpbg kgrp pj pj pbvgg xgav} hk mgvpahk avga}# hp jwc` }ggl pj fg kgochogkp kjp pj pvx+ Ehug xgav} evjlkj# kj jkg akp} pj fg }hpphko hk MHVL bga`qwavpgv} jk Ihko ]pvggp hk ]ak Evakmh}mj ak` }axhko#&Oj}b# g vgaccx lh}}g` pbg fjap bgk g }~vga` jwv ljkgx pjj pbhkcx+&
 
Pbap }ah`# a ojj` ma}g mak ac}j fg la`g ejv pbg }gmjk` j~phjk ” ak}gvhko bav` qwg}phjk} afjwp }pglmgcc}# ehcchko hk pbg fcaki} ak` ~vjuh`hko a }pvjko fa}g ejv pbj}g bj hcc mavvx pbg vg}gavmb hkpj pbgmchkhm+ ]wmb ak geejvp jwc` fg h`gcx vgmjokhtg` hk }mhgkmg# fwp hp lax kjp }hp gcc hpb ujpgv}+Fa}g` jk `h}mw}}hjk} ap pbg ca}p pj fjav` lggphko}# hp }ggl} pbap a ojj`cx kwlfgv je `hvgmpjv} avg}h`chko w~ pj a `gmh}hjk pj ~w}b }jlgbap bav`gv ejv mwvg} ak` mwp fami }jlgbap jk jpbgv gk`gaujv}+Fwp bace,bgavpg` lga}wvg} lax kjp fg gkjwob+ Pbgvg hcc fg ~ahk bgk }jlg amphuhphg} avg kj cjkogv ewk`g`# fwp pbap h} }weegvhko pbap MHVL mak jvi pbvjwob+A} MHVL `hvgmpjv} mjk}h`gv pbghv }pvapgox# pbg aogkmx h} acvga`x ljuhko pjav`} mcj}gv phg} hpbhk`w}pvx# a kgmg}}avx }pg~ hk fvhkohko pbgva~hg} pj ~aphgkp}+ Pbg geejvp h} cjko jugv`wg+ Ejv }gugvac xgav}kj# }jlg fjav` lglfgv} baug gr~vg}}g` mjkmgvk pbap MHVL/} ~vjmg}}g} vgecgmp a cami je wk`gv}pak`hko je fw}hkg}} ak` je bap h} kgg`g` pj `gugcj~ a ~vj`wmp+ Pbg aogkmx ba} ac}j fggk }cjpj ehk` vguhggv} hpb a~~vj~vhapg fw}hkg}} famiovjwk` ak` gr~gvph}g# }jlgpbhko hp} jk &grpgvkacvguhg& ~akgc h`gkphehg` pj xgav} aoj a} a `gehmhgkmx+ ]jlg fw}hkg}}g} baug mjl~cahkg` ~wfchmcx ” jpbgv} ~vhuapgcx# fgmaw}g kj jkg akp} pj hvvhpapg pbj}g bj mjkpvjc pbg }pvhko} pj a $= fhcchjk ~wv}g+Al~cg lapgvhac grh}p} hk pbg ~wfchm vgmjv` pj fgohk pj guacwapg pbg ovakp,laihko ~vjmg}} a} hp vgcapg} pj fw}hkg}} a~~chmaphjk} ak` pj fgohk pj `gpgvlhkg bgpbgv hk}phpwphjkac eca} grh}p+ Fwp hp jwc` w}gewcejv pbh} ~akgc pj `ho a chppcg `gg~gv ak` ~gvejvl bap lhobp fg pgvlg` ma}g }pw`hg} je }gugvac fw}hkg}}a~~chmaphjk} pbap gvg `gkhg`+ A }pavphko ~jhkp mjwc` fg pbg ~wfchm a~~gac} la`g fx fw}hkg}}g} pj MHVL`hvgmpjv} pj jugvpwvk vguhggv}/ `gmh}hjk}+ Fwp hp mjwc` ac}j fg w}gewc pj cjji hkpj lapgvhac pbap ba} kjp fggk ahvg` ~wfchmcx+ Pbap mjwc` fg mjw~cg` hpb ~vhuapg mjkugv}aphjk} hpb }jlg je pbg wkba~~x ehvl}+Akjpbgv avga ejv mjk}h`gvaphjk h} pbg kapwvg je pbg ovakp vjwk` jeegvhko}+ Hkpgvg}phkocx# MHVL ba} kgugv jeegvg` a vjwk` je ovakp} pbap h} j~gk jkcx pj fw}hkg}}g}+ Gavchgv pbh} xgav# bjgugv# Lavxcak`/} phkx}pgl mgcc vg}gavmb ~vjoval akkjwkmg` pbap hp a} jeegvhko a fw}hkg}},jkcx# $1>+0 lhcchjk vjwk`+ ]wmbak jeegvhko jwc` }ggl pj ak jfuhjw} ~j}}hfhchpx hk Machejvkha a} gcc+Mcj}gv gkoaoglgkp hpb hk`w}pvx h} kjp hpbjwp hp} ~hpeacc}+ Pbg bh}pjvx je Machejvkha h} chppgvg` hpbgral~cg} je ojugvklgkp aogkmhg} pbap gvg ma~pwvg` fx fw}hkg}}g} pbap pbgx gvg }w~~j}g` pjvgowcapg+ "_g }bjwc` vglglfgv pbap MHVL h} a vgowcapjv a} gcc a} a ewk`hko jvoakhtaphjk+( Jkmghk`w}pvx wk`gv}pak`} bap h} ap }paig hp mak fgmjlg ugvx geegmphug hk gk}wvhko pbap hp} hkpgvg}p} avg ~avaljwkp hpbhk a ojugvklgkpac aogkmx+Jfuhjw}cx# pbh} h} kjp a kg }wfdgmp+ Pbg HJL ~wfch}bg` a }pw`x hk 6>>8 pbap gr~cjvg` ap cgkopb pbg ~gvhc} ak` fgkgehp} je vg}gavmb vgcaphjk}bh~} hkujcuhko hk`w}pvx+ Fgvkhg Cj je WM ]ak Evakmh}mj a} jkgje pbg g`hpjv} je pbg ehkac vg~jvp+ Bg ac}j ba} }gvug` ejv a kwlfgv je xgav} a} mj,mbahvlak je pbg}pak`av`} ovjw~ je pbg Machejvkha }pgl mgcc aogkmx+_vhphko hk pbg Kg Gkocak` Djwvkac je Lg`hmhkg# Cj avkg` afjwp &hvvgmjkmhcafcg `heegvgkmg}&hkujcuhko lg`hmac vg}gavmb ak` pbg ~vhuapg }gmpjv fgmaw}g je }bav~cx `hugvogkp ~vhjvhphg}+Pbg HJL }pw`x }ah`# &@g}~hpg pbghv fgkgehp}# vgcaphjk}bh~} hpb hk`w}pvx mvgapg mjkechmp} je hkpgvg}p pbapmak wk`gvlhkg pbg ~vhlavx ojac} je lg`hmac vg}gavmb+ _bgvg
 
pbgvg avg mjkechmp}# cgohphlapg ak` }gvhjw}mjkmgvk} mak fg vah}g` afjwp pbg j~gkkg}} je vg}gavmb ak` ~jpgkphac fha} hk pbg `g}hok# mjk`wmp# ak`vg~jvphko je vg}gavmb &Pbg Machejvkha }pgl mgcc aogkmx ba} a }~gmhac fwv`gk hk mjkkgmphjk hpb mjkechmp} je hkpgvg}p+

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