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NSF Mimicking Breast Carcinoma

NSF Mimicking Breast Carcinoma

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Published by gasfgd
Nephrogenic systemic fibrosis, previously known as nephrogenic fibrosing dermopathy, is a newly recognized systemic fibrosing disorder primarily affecting patients with chronic renal failure. Patients with skin involvement often develop papules and plaques with peau d’orange surface changes. The lower extremities and trunk are most commonly affected. The most important histologic differential diagnosis is with scleromyxedema. To our knowledge, we report the first case of nephrogenic systemic fibrosis involving the breasts of a 61-year-old woman with end-stage renal disease, clinically mimicking inflammatory breast carcinoma. We propose that nephrogenic systemic fibrosis be considered in the differential diagnosis as a rare possibility when cutaneous changes in the breast suggest inflammatory breast carcinoma in a patient with renal failure.

(Arch Pathol Lab Med. 2007;131:145–148)
Nephrogenic systemic fibrosis, previously known as nephrogenic fibrosing dermopathy, is a newly recognized systemic fibrosing disorder primarily affecting patients with chronic renal failure. Patients with skin involvement often develop papules and plaques with peau d’orange surface changes. The lower extremities and trunk are most commonly affected. The most important histologic differential diagnosis is with scleromyxedema. To our knowledge, we report the first case of nephrogenic systemic fibrosis involving the breasts of a 61-year-old woman with end-stage renal disease, clinically mimicking inflammatory breast carcinoma. We propose that nephrogenic systemic fibrosis be considered in the differential diagnosis as a rare possibility when cutaneous changes in the breast suggest inflammatory breast carcinoma in a patient with renal failure.

(Arch Pathol Lab Med. 2007;131:145–148)

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Published by: gasfgd on Apr 27, 2012
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11/07/2012

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s|bblstld pld|cimb thl dasl ae lpythpa~ailtim im ~ftilmtsrith plmfj dyse|mctiam simcl plcao`imfmt lpythpa~ailtimhfs ~atlmtifj st`pablmic ~pa~lptils- Thl a~tiofj ofmfbl/olmt is mat kmarm simcl tplftolmt dftf fpl fufijf`jl eapamjy f sofjj m|o`lp ae cfsls- E|pthlpoapl* it is diestc|jtta fsslss cjimicfj io~paulolmt* fs ma stfmdfpd eap stfbimbthl dislfsl lxists- ‘‘Io~paulolmt’blmlpfjjy io~jils pl/d|ctiam ae imd|pftiam* pld|ctiam ae camtpfct|pls* ap io/~pauld oa`ijity-
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Imfffooftapy cfpcimaof is chfpfctlpiwld `y lpythlof ae thl ofoofpy skim rith thicklmimb* ls/~lcifjjy ft thl ldbl ae thl lpysi~ljaid fplf-
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Thl skim ofyshar
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