Searle (now part of Pfizer), registered misoprostol,as Cytotec, worldwide (except for most sub-Saharan African countries) for the preventionof gastric ulcers associated with NSAIDs.
Misoprostol is widely available as genericformulations and, in many countries, cheaply.
Has begun to be registered for obstetricindications in various countries.
Included on WHO Model List of Essential Medicinesfor induction of labour; incomplete abortion; withmifepristone for early abortion; and for prevention ofPPH.
Prevention and Management of Postpartum Hemorrhage andPre-eclampsia/Eclampsia. Dhaka, Bangladesh, 4-6 May 2012