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Introduction to Bioinformatics

Introduction to Bioinformatics

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Categories:Types, School Work
Published by: Nandagopal Sivakumar on May 05, 2012
Copyright:Attribution Non-commercial

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01/06/2013

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BIOINFORMATICS
AN INTRODUCTION
 
DEFINITION:
 
Bioinformatics is the process of conceptualizing biology in terms of molecules (in the sense of physical-chemistry) and then applying
informatics
 techniques (derived from disciplines such as Applied Mathematics, Control Systems,Image Processing, Logical Computation and Statistics) to understand and organize theinformation associated with these molecules, on a large-scale.
Bioinformatics is the application of computer scienceandinformation technologyto the field of biologyandmedicine.Bioinformatics deals with algorithms, databases and information systems, web technologies, artificial intelligence and soft computing, informationand computation theory, software engineering, data mining, image processing, modeling andsimulation, signal processing, discrete mathematics, control and system theory, circuit theory,and statistics. Bioinformatics generates new knowledge as well as the computational tools tocreate that knowledge
.
In order to study how normal cellular activities are altered in different disease states, thebiological data must be combined to form a comprehensive picture of these activities.Therefore, the field of bioinformatics has evolved such that the most pressing task nowinvolves the analysis and interpretation of various types of data. Important sub-disciplineswithin bioinformatics and computational biology include:
 
The development and implementation of tools that enable efficient access to, and use andmanagement of, various types of information.
 
The development of new algorithms (mathematical formulas) and statistics with which toassess relationships among members of large data sets. For example, methods to locate agene within a sequence, predict protein structure and/or function, and cluster proteinsequences into families of related sequences.The primary goal of bioinformatics is to increase the understanding of biological processes.What sets it apart from other approaches, however, is its focus on developing and applyingcomputationally intensive techniques to achieve this goal.

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