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Table Of Contents

executive summary
1.1 Chapter objectives
1.2 Purpose of the guidelines
1.3 Target audience
1.4 Scope
1.5 Why a new edition?
1.6 methodology
1.7 International Standards for Tuberculosis Care
1.8 Expiry date
Case defnitions
2.1 Chapter objectives
2.2 Purposes of defning a Tb case
2.3 Case defnitions
2.4 anatomical site of Tb disease
2.5 bacteriological results
2.6 History of previous treatment: patient registration group
2.7 HIV status
standard treatment regimens
3.1 Chapter objectives
3.2 aims of treatment
3.4 Standard regimens for defned patient groups
3.5 new patients
3.6 Previously treated patients and multidrug resistance
3.7 Standard regimens for previously treated patients
3.8 overall considerations in selecting a country’s standard regimens
Monitoring during treatment
4.1 Chapter objectives
4.2 monitoring the patient
4.4 Extrapulmonary Tb
4.5 recording standardized treatment outcomes
4.6 Cohort analysis of treatment outcomes
4.7 management of treatment interruption
4.8 Prevention of adverse effects of drugs
4.9 monitoring and recording adverse effects
4.10 Symptom-based approach to managing side-effects of anti-Tb drugs
5.2 HIV testing and counselling for all patients known or suspected to have Tb
5.3 HIV prevention in Tb patients
5.4 Tb treatment in people living with HIV
5.5 Co-trimoxazole preventive therapy
5.6 antiretroviral therapy
5.7 drug susceptibility testing
5.8 Patient monitoring during Tb treatment
5.10 HIV-related prevention, treatment, care and support
supervision and patient support
6.1 Chapter objectives
6.2 roles of the patient, Tb programme staff, the community and other providers
6.3 Supervised treatment
6.4 using a patient-centred approach to care and treatment delivery
6.5 Prevention of treatment interruption
Treatment of drug-resistant tuberculosis
7.1 Chapter objectives
7.2 Green light Committee Initiative
7.5 Programmatic strategies for treatment of mdr-Tb
7.6 Selection of the country’s standard mdr-Tb regimen
7.7 Selection of individualized mdr-Tb regimens
7.8 monitoring the mdr-Tb patient
7.9 duration of treatment for mdr-Tb
7.10 Treating Tb with resistance patterns other than mdr
7.11 recording and reporting drug-resistant Tb cases, evaluation of outcomes
Treatment of extrapulmonary TB and of TB in special situations
8.1 Chapter objectives
8.2 Treatment of extrapulmonary Tb
8.4 Treatment regimens in special situations
Annexes
essential frst-line antituberculosis drugs1
summary of evidence and considerations underlying the recommendations
TB treatment outcomes
implementation and evaluation of the fourth edition
suggestions for future research
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WHO Treatment of Tuberculosis Guidelines 2010

WHO Treatment of Tuberculosis Guidelines 2010

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Published by: Samuel Rmj Butar-butar on May 06, 2012
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05/06/2012

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