Names:Vessels of Death
How would you explain what “angiogenesis” is to a relative that had cancer?
Name 1 major pro-angiogenic factor and 1 major anti-angiogenic factormadein the body.
List 2 conditions in which therapeutic angiogenesis may be a benefit. Whatare the possible side effects?
What was the unexpected result that Judah Folkman often observed when heremoved a patient’s primary tumor?
How did Folkman’s observation help to spark the idea of anti-angionesis as atherapy?
What type of substances are angiostatin and endostatin? Why is thisimportant?
Why does anti-angiogenic therapies normally not attack normal vasculature?
Does anti-angiogenic therapy work as a single therapy? Explain.
Why does it seem that treating a cancer patient with an antiangiogenictherapy also assist in chemotherapy?