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Agents Teratogens

Agents Teratogens

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Published by Haider Rahman

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Published by: Haider Rahman on Jun 18, 2012
Copyright:Attribution Non-commercial

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06/18/2012

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Agent
 
Malformations
 
Rubella*
 
Cataract, glaucoma, heart defect, deafness, erosion of the teeth
CMV*
 
Microcephaly(small brain), blindness, mental retardation
 
HSV
 
Microphthalmia(small eyes), microcephaly, retinal dysplasia
 
HIV
 
Microcephaly, growth retardation
 
Toxoplasmosis
 
Hydrocephalus, cerebral calcification, microphthalmia (braingets hard, and most brain gets blocked )
 
Syphilis
 
Mental retardation, deafness (damage of organ of corti)
 
 
Thalidomide
 
Limb defect, heart malformation
pheocomlia
Aminopterin
Anencephaly, hydrocephaly, cleft lip and palate
 
Phenytoin
 
Facial defect, mental retardation, fetal hydantoin syndrome
 
Valproic acid
 
Neural tube defects, heart, craniofacial and limb anomalies
 
Warfarins
Chondrodysplasia, microcephaly
ACE inhibitors
 
Growth retardation, fetal death
 
Cocaine
 
Growth retardation, microcephaly, gastroschisis, abnormal behavior
 
Trimethadione
Cleft palate, heart defects, urogenital and skeletal abnormality
 
Amphetamines
 
Cleft lip and palate, heart defects
 
 
Industrial solvents
 
Low birth weight, craniofacial and limb defects
 
Lead
 
Growth retardation, neurological disorders
 
Mercury
 
Neurological symptoms
Lithium
 
Heart malformations
 
Alcohol
 
Fetal alcohol syndrome, short palpebral fissures, maxillaryhypoplasia(small face), heart defects, mental retardation
 
Cigarette smoking
 
Intrauterine growth retardation, premature delivery
 

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