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Improving Biopharmaceutical Process Scaleup and Tech Transfer

Improving Biopharmaceutical Process Scaleup and Tech Transfer

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Published by: Kirbyx on Jun 26, 2012
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Impi BipmcticPcss Scp & Tc Ts
 
Introduction
*
 
CONTENTS
i bamacca dm, ca ad cadw a cca dg a b c ad maag dc qay. tcgym b ccy ad, a m-dcay c a qwdg  a wd maa ad qm, a c aaby, ad cca qay ab   dc.t pamacca Qay by Dg amw, iCh Q10, FDA’ 2004pc Aayca tcgy (pAt) Gdac ad 2011 pc vadaGdac ca  maac d a agy  c adaayca md a, ada ad c qay mm.hw,  ay bamacca c,  da  a  w  q ad acca c mam, ycay g ddyg, h ad cdcy .t -c mmaz b acc  bamacca cca, a w a cgy ad aayca md a m a amacca maacg ad gg cma, w  agg   a Do, h ad cdcy  ay  gc b.
introDuCtion
 
t md c c bc a b ccycad   m ga a 25,000l gd gg dama ad g cdadg. t a’ ad by accd, ba by bcg a ag a ymacaac  caaczg  bac’ caabad dc, dg b ad ab ca- cd, ad abg ad maag c ca. t maac a dy addcm aa b acc  a cGMp cc a a d  b  a a aacc ad d g-qay bamacca a  a my ad ab ma.idyg ad dcmg bac a bacc aw  m b cg by g y dca  a, gg adcca a w   bac c.sad ag   dc  am  “bawdg” a  w a g ad  maag   aa cc   m my , w  d  bg a aabad ab y  bamacca.W  da  md, w a    dcmb acc a w a ad  bcg,m aby   aa  qm dg ad ac c.
BioReactoR opeRational excellence:
Bst Pctics m Sc-p t Ct
i bfr, w f s-, rss  r s b sr  -  rr    ss r .
By BRian J. StampeR and cillian mccaBe, BiopRoceSS ReSeaRch and development, eli lilly and company
BIoreaCTor deSIgn
sag  w   bac dg ca may c  b y a. o y bacdg  a d  b dmad  mac  gmc may bw bac:maag ac a, m zg a, macg a ad ba z ad ca w gayca  baby  cc a ca. A ydgd bac ca ad  dcd qacaad c ada mam, a w a cadaa c b ad aa cc.A y ac  bc ca- cc  dg   ag. o, w ag aad   dc bac w y ag  d   d bac. W ay  ag a b zd w  dy,w a ccy mmd    dd ad ag . t dd  yd agbbb ad a w la (wc w b dcdbw), w  ag  yd ma bbb ada y g la c a a ga am  yg

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