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Alcohol Presentation

Alcohol Presentation

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Published by Samer Farhan

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Published by: Samer Farhan on Jun 27, 2012
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06/27/2012

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Alcohol & Interactions
 
Sept 2006
Dr B Russell
 
 
Doses ~0.5-1 g/kg with 40-50 g doses common cf. mgdoses.
T
m
ax
~ 30-90 minutes, absorption from stomach,majority from small intestine due to greater surfacearea.
5-10% excreted by breath, skin and urine
8-10 g/hr of ethanol metabolized
Mellanby effect…..
 
Bioavailability -
females 90% v’s males 75%, less
gastric alcohol dehydrogenase activity in females
Dose effect 
 
Training and experience
Memory concentration, insight dulled then lost.
Confident, expansive, vivacious, mood swings
 Acute use
latency to sleep and REM sleep
in sleep latency disappears with 3 or more nights of ingestion
Dose dependent effects
 – 
 
calming, sleep,unconsciousness, surgical anaesthesia, coma, fataldepression respiratory of & cardiovascular 
Intoxication - cessation of g/i motor and secretorymotor functions so get pylorospasm and vomiting. Canoccur independently from local reflex irritation.

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