That’s when the FDA informed the company of their intent to pull it and the company then voluntarily took itoff the market.” (
Source: The Senior Dogs Project
<http://www.srdogs.com/Pages/proheart6.html>Pfizer was allowed to re-market the drug in 2008 with the following stipulations: Pfizer agreed to addadditional warning labels to the drug packaging, and agreed to mandate that pet owners be given a drug factsheet and be made to sign an “informed consent” document. Pfizer went even further as to mandate web-based training for veterinarians who gave the drug, and issued several “Dear Doctor” letters to allveterinarians regarding the adverse effects of the drug. (
Read one of the “Dear Doctor” letters here
<https://animalhealth.pfizer.com/sites/pahweb/US/EN/Products/Pages/ProHeart%c2%ae6%28moxidectin%29.aspx>We were never shown a fact sheet on the drug, never “advised of the risks”, and certainly not given anOwner Consent Form” by our vet to sign. (In hindsight, we feel that we should have asked more questionsabout the drug, but we trusted our veterinarian.) If the side effects had been presented to us as they have inour research, we would NOT have consented to have Pro Heart 6 administered to our dogs.We also found some literature suggesting that ProHeart 6 should not be administered at the same time asvaccinations: “Allergic reactions, sometimes serious, have been reported when ProHeart 6 and vaccinationshave been given at the same time. Talk to your veterinarian about the risks of administering ProHeart 6 atthe same time as vaccinations.” (
Source link here.
) Our vet administered ProHeart 6 at the same time asJack rabies vaccine, and distemper/bordetella.The drug’s information page from Drugs.com states the following: “Owners should be advised of the potentialfor adverse reactions, including anaphylaxis, and be informed of the clinical signs associated with drugtoxicity. Owners should be advised to contact their veterinarian immediately if signs of toxicity are observed.The vast majority of patients with drug related adverse reactions have recovered when the signs arerecognized and veterinary care, if appropriate, is initiated.” (
recognize that something was going on with our dog, we did what we thought good pet ownersare supposed to do. We took him back to the vet. The vet should have recognized that he was having anadverse reaction to the ProHeart6 that she administered to him (
our “informed” consent) only weeksearlier and treated him appropriately. If the veterinarian had recognized his symptoms, he could haverecovered. She did not, and as a result, our otherwise healthy dog died. Now, we are left waiting on the drugto work its way out of our remaining dog’s system praying that she does not fall victim to the same fate.Stories of dogs that died as a result of being administered this drug are abundant. Check out any of thefollowing links for more information, and
please, ask for all of the facts, side effects, and moreinformation when your vet (or doctor) recommends this drug (or any drug)
. ProHeart 6 provides noadditional benefits or protection than safer, oral heartworm preventatives.
Letters & Data by the Drug Manufacturer from the FDA’s Website:
July 22, 2002 “Dear Doctor” Letter warning of additional “adverse reactions”
June 19, 2003 “Dear Doctor” Letter advising of label changes due to “adverse reactions”
“Risk Minimization Action Plan” for the Re-Introduction of ProHeart 6 to the Market