Portal triad:Portal arterioleportal venulebile ductuleSinusoidsCentral vein of lobuleLeads to hepaticveinKupffer cellsHepatocytes
Sinusoids areformed offenestratedendothelium.
Sinusoids areformed offenestratedendothelium.Hepatocytesperform all thefunctions of theliver, dividing upthe taskaccording todemands.
Hepatocytesperform all thefunctions of theliver, dividing upthe taskaccording todemands.
From hepaticarteryFrom hepaticportal veinTo bile duct
Structure of the liver -The liver is composed mostly of cells known ashepatocyteswhich perform the functions listed above. They have the abilityto shift functions so their efforts can be directed at what is most needed.They can also divide to repair and replace tissue. Cirrhosis is a conditionwhich can occur in the liver and other organs in which the cellsare damagedas a result of toxins, pathogenic organisms, etc. Cirrhosis causes thickeningand fibrosis and can progressively damage the liver to the pointit can nolonger recover by replacing its cells. Other functions also suffer as morehepatocytesbecome committed to detoxification.The liver is organized into lobes and lobules. Each lobule is served by abranch from the portal vein, the hepatic artery and a bile duct.Blood fromthe artery and vein mixes in sinusoids passing through the lobule.Hepatocytesline the sinusoids and withdraw digestive endproducts, toxins,etc. from the blood. Into the blood the put urea, glucose, and othersubstances. Into the bile ductulethey put bile to be taken to the gallbladderand common bile duct. Kupffercells are found inside the sinusoids tophagocytizedebris, rbc, and pathogens.