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All 3 Chapters for Advancing Site Updated Mar '10

All 3 Chapters for Advancing Site Updated Mar '10

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Published by 5wishes

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Published by: 5wishes on Jul 07, 2012
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02/25/2013

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Thyroid 101
9
 
Chapter 1
Thyroid 101
N order to understand the causes of low thyroid hormone symptoms it isimportant to understand some of the basics about the thyroid gland, how it
works and what causes problems. Here‟s a very simple introduction to all the
characters that play their part in thyroid health.
Pituitary
The pituitary is a pea-sized gland in the brain. When thyroid hormones in thebloodstream go down the pituitary makes a hormone called thyroid stimulatinghormone or TSH.
TS
This hormone travels through the bloodstream to the thyroid gland and
stimulates the thyroid to make more of its hormones. Here‟s the thyroid.
 
I
 
Thyroid 101
10
 
Well, OK. I thought this was better than a bloody thyroid gland. Anyway, whenyour thyroid is stimulated by TSH it secretes primarily two thyroid hormones.One is called T4 or thyroxine.T4 is the primary hormone made by the thyroid. It is also known as theprohormone or mother-hormone because it can become other thyroid hormones.Notice the 4 atoms of iodine.
T4 is inactive. It doesn‟t do anything for the body‟s metabolism or the making
of energy. It must be converted into T3.This is T3 with one less atom of iodine. It is the active thyroid hormone. It isalso called triiodothyronine. The conversion of T4 to T3 happens primarily inthe liver. Conversion simply happens by removing 1 atom of iodine.
T4
IodineIodineIodineIodine
T3
IodineIodineIodine
T4T4T4
 
Thyroid 101
11
 
That covers some of the basics of thyroid hormones so now let‟s review some of 
the most common questions about the thyroid.
What is Hypothyroidism?
Hypothyroidism simply means that the thyroid isn‟t making enough T4 and T3
and so these two hormones are low in the blood and on blood tests.There are two types of Hypothyroidism, one is Primary Hypothyroidism and theother is Secondary Hypothyroidism.With Primary there is plenty TSH and thus plenty of stimulation but the thyroidgland isn
t able to respond.The blood test with Primary Hypothyroidism will show high TSH and low levelsof T4 and T3.Secondary Hypothyroidism is very different when looking at blood test results.With Secondary TSH is low for various reasons and since TSH is low thethyroid is not getting enough stimulation to make its hormones.So with Secondary the blood test will show low TSH and low T4 and T3.Note that both conditions have low thyroid hormones so the way a person withPrimary Hypothyroidism feels and the way a person with SecondaryHypothyroidism will feel are pretty much the same. This is why lab testing isso important.
T4
IodineIodineIodineIodine
T3
Iodine
 
IodineIodine
T4
IodineIodineIodineIodine
T3
Iodine
 
IodineIodine
TSH
TSH

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