steelgraham
Activin a and Follistatin in Systemic Inflammation
from steelgraham in Research, Science
Inflammation is a complex process regulated by a cascade of cytokines and growth factors. This review summarizes the emerging evidence / implicating activin A and follistatin in the inflammatory process. Our recent studies have highlighted that activin A is released early in the / process as part of ...
Follistatin Gene Delivery Enhances Muscle Growth and Stre...
from steelgraham in Research, Health & Medicine
Antagonists of myostatin, a blood-borne negative regulator of muscle growth produced in muscle cells, have / shown considerable promise for enhancing muscle mass and strength in rodent studies and could serve as / potential therapeutic agents for human muscle diseases. One of the most potent of these...
Open Science at Web-Scale - Optimising participation and ...
from steelgraham in Research, Science
This Report has attempted to draw together and synthesise evidence and opinion associated / with data-intensive open science from a wide range of sources. The potential impact of dataintensive / open science on research practice and research outcomes, is both substantive and / far-reaching. There are i...
Open Science at Web-Scale - Optimising participation and ...
from steelgraham in Research, Science
This Report has attempted to draw together and synthesise evidence and opinion associated / with data-intensive open science from a wide range of sources. The potential impact of dataintensive / open science on research practice and research outcomes, is both substantive and / far-reaching. There are i...
steelgraham
scribbled: source = http://www.jisc.ac.uk/Home/publicatio...
r a n s o m d e m a n d
from steelgraham
R / We haz yo / A / N / S / O / M / D / E / M A / N D / ur stuff. Star at 3pm, unless you meet our demands, tart
Genome-wide association study identifies 19p13.3 (UNC13A)...
from steelgraham in Research, Health & Medicine
"ALS, also known as Lou Gehrig’s disease, is a neurodegenerative disorder / characterized by progressive wasting and weakness of limb, bulbar / and respiratory muscles. The disease is caused by loss of motor / neurons in the spinal cord, brain stem and motor cortex and can occur / at any time in adul...
Straight talk with…James Ironside
from steelgraham in Research, Health & Medicine
Would you entrust your brain to a bank? Well, many people do after they die, and such brain banks—often funded by government / agencies or disease charities—are essential for neuroscience research. They collect and store the healthy and diseased brain / specimens that neuroscientists need to explor...
Design, power, and interpretation of studies in the stand...
from steelgraham in Research, Health & Medicine
Abstract / Identification of SOD1 as the mutated protein in a significant subset of familial amyotrophic lateral sclerosis (FALS) cases / has led to the generation of transgenic rodent models of autosomal dominant SOD1 FALS. Mice carrying 23 copies of the / human SOD1G93A transgene are considered th...
Rhes, A Striatal Specific Protein, Mediates Mutant-Huntin...
from steelgraham in Research, Health & Medicine
ABSTRACT / Huntington’s disease (HD) is caused by a polyglutamine repeat in the protein huntingtin (Htt) with / mutant Htt (mHtt) expressed throughout the body and similarly in all brain regions. Yet, HD / neuropathology is largely restricted to the corpus striatum. We report that the small guanin...
Structural and Biophysical Properties of the Pathogenic S...
from steelgraham in Research, Science
ABSTRACT: Over 100 mutations in the gene encoding human copper-zinc superoxide dismutase (SOD1) / cause an inherited form of the fatal neurodegenerative disease amyotrophic lateral sclerosis (ALS). Two / pathogenic SOD1 mutations, His46Arg (H46R) and His48Gln (H48Q), affect residues that act as cop...
from steelgraham
Search / Sign in or Join FriendFeed / FriendFeed is the easiest way to share online. Learn more » / Joi
Depletion of TDP-43 Affects Drosophila Motoneurons Termin...
from steelgraham in Research
Pathological modifications in the highly conserved and ubiquitously expressed heterogeneous ribo- / nucleoprotein TDP-43 were recently associated to neurodegenerative diseases including amyotro- / phic lateral sclerosis (ALS), a late-onset disorder that affects predominantly motoneurons / [Neuman...
Uniquely Hominid Features of Adult Human Astrocytes - Obe...
from steelgraham in School Work
Defining the microanatomic differences between the human brain and that of other mammals is key to understanding its unique / computational power. Although much effort has been devoted to comparative studies of neurons, astrocytes have received far less / attention.Wereport here that protoplasmic a...
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steelgraham's Documents
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Subcutaneous IGF-1 is Not Beneficial in 2 ... 621 Reads |
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Skeletal Muscle is a Primary Target of SOD... 753 Reads |
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Intraventricular Pentosan Polysulphate in ... 1,893 Reads |
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Water and the Biology of Prions and Plaque... 922 Reads |
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Between Biological and Digital Memory ... 1,008 Reads |
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Identification of the Heparan Sulfate Bind... 466 Reads |
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Creutzfeldt-Jakob Disease - Hopes for Ther... 1,090 Reads |
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