Documents tagged with disruptors

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Do Perfluoroalkyl Compounds Impair Human Semen Quality?

Perfluoroalkyl acids (PFAAs) are found globally in wildlife and humans and are suspected to act as endocrine disruptors. There are no previous reports of PFAA levels in adult men from Denmark or of...
  • ehponline published this 06 / 15 / 2009
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Prenatal Exposure to Bisphenol A at Environmentally Relevant Doses Adversely Affects the Murine Fema

Exposure to endocrine-disrupting chemicals during critical developmental periods causes adverse consequences later in life; an example is prenatal exposure to the pharmaceutical diethylstilbestrol ...
  • ehponline published this 06 / 15 / 2009
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Endocrine Disruptors in the Workplace, Hair Spray, Folate Supplementation, and Risk of Hypospadias:

Hypospadias is one of the most common urogenital congenital anomalies affecting baby boys. Prevalence estimates in Europe range from 4 to 24 per 10,000 births, depending on definition, with higher ...
  • ehponline published this 03 / 16 / 2009
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Analysis of Endocrine Disruption in Southern California Coastal Fish Using an Aquatic Multispecies M

Endocrine disruptors include plasticizers, pesticides, detergents, and pharmaceuticals. Turbot and other flatfish are used to characterize the presence of chemicals in the marine environment. Unfor...
  • ehponline published this 03 / 16 / 2009
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Environment and Obesity in the National Children’s Study

In this review we describe the approach taken by the National Children’s Study (NCS), a 21-year prospective study of 100,000 American children, to understanding the role of environmental factors in...
  • ehponline published this 03 / 16 / 2009
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Long-Term Effects on Hypothalamic Neuropeptides after Developmental Exposure to Chlorpyrifos in Mice

Increasing evidence from animal and human studies indicates that chlorpyrifos (CPF), similar to other organophosphorus insecticides still widely used, is a developmental neurotoxicant. Developmenta...
  • ehponline published this 03 / 10 / 2009
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The Polybrominated Diphenyl Ether Mixture DE-71 Is Mildly Estrogenic

Polybrominated diphenyl ethers (PBDEs) are widely found in the environment, and they may act as endocrine disruptors.
  • ehponline published this 10 / 08 / 2008
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Meeting Report: Measuring Endocrine-Sensitive Endpoints within the First Years of Life

An international workshop titled “Assessing Endocrine-Related Endpoints within the First Years of Life” was held 30 April–1 May 2007, in Ottawa, Ontario, Canada. Representatives from a number of pr...
  • ehponline published this 10 / 07 / 2008
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Early-Onset Endocrine Disruptor–Induced Prostatitis in the Rat

Androgens are critical for specifying prostate development, with the fetal prostate sensitive to altered hormone levels and endocrine-disrupting chemicals (EDCs) that exhibit estrogenic or antiandr...
  • ehponline published this 10 / 07 / 2008
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Region-Specific Growth Effects in the Developing Rat Prostate Following Fetal Exposure to Estrogenic

Exposure to environmental endocrine disruptors is a potential risk factor for humans. Many of these chemicals have been shown to exhibit disruption of normal cellular and developmental processes in...
  • ehponline published this 10 / 07 / 2008
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Hydroxylated Metabolites of the Polybrominated Diphenyl Ether Mixture DE-71 Are Weak Estrogen Recept

Polybrominated diphenyl ethers (PBDEs) are widely found in the environment and are suspected endocrine disruptors. We previously identified six hydroxylated metabolites of PBDE (OH-PBDEs) in treate...
  • ehponline published this 10 / 07 / 2008
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