Documents tagged with kinase

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Cell-Based Assay for Monitoring Kinase Signaling Pathways

First paper describing a cell-based assay for assessing protein phosphorylation and kinased pathway activation for drug development.
  • dmichaelolive published this 09 / 19 / 2009
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7 p.
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Cell-Based Assay for Monitoring Kinase Signaling Pathways

Research Paper reviews current methodologies to analyze kinase pathways, one of the key targets for anti-cancer drug development.
  • dmichaelolive published this 09 / 19 / 2009
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7 p.
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Structure-Activity–Depend ent Regulation of Cell Communication by Perfluorinated Fatty Acids using in

Perfluoroalkanoates, [e.g., perfluorooctanoate (PFOA)], are known peroxisome proliferators that induce hepatomegaly and hepatocarcinogenesis in rodents, and are classic nongenotoxic carcinogens tha...
  • ehponline published this 04 / 22 / 2009
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10 p.
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Diesel Exhaust Particles Activate the Matrix-Metalloproteinase- 1 Gene in Human Bronchial Epithelia i

Diesel exhaust particles (DEPs) are globally relevant air pollutants that exert a detrimental human health impact. However, mechanisms of damage by DEP exposure to human respiratory health and huma...
  • ehponline published this 03 / 20 / 2009
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9 p.
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The Protective Mechanism of Antioxidants in Cadmium-Induced Ototoxicity in Vitro and in Vivo

Several heavy metals have been shown to have toxic effects on the peripheral and central auditory system. Cadmium (Cd2+) is an environmental contaminant showing a variety of adverse effects. Given ...
  • ehponline published this 10 / 07 / 2008
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5 p.
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JNK isoforms review

JNK isoforms review regarding autophosphorylation and quaternary structure properties
  • pascual published this 01 / 25 / 2008
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21 p.
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JNK2 retreat

Autophosphorylation properties of JNK2
  • pascual published this 08 / 28 / 2007
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10 p.
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autophosphorylation of JNK2

identification of autophosphorylated residues in JNK2
  • pascual published this 07 / 12 / 2007
  • 431 reads
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