What if curing cancer was as easy as getting an injection? That’s just what a pair of studies published this week in Nature tried to figure out.

The two teams of researchers conducted independent Phase I trials of personalized vaccines designed to prime the patients’ immune systems against melanomas, a category of skin cancers. In a scientific double whammy, both studies found that their vaccines—sometimes in combination with other immunotherapies—were able to prevent recurrence of the cancers in nearly all their subjects.

“We can safely and feasibly create a vaccine that is personalized to an individual’s tumor,” says Catherine Wu, senior author of one of the studies and associate professor at Dana-Farber Cancer Institute in Boston. “It’s not one-size-fits-all—rather, it’s tailored