Los Angeles Times

Scientists engineer proteins that caused obese animals to lose weight and lower cholesterol

As the U.S. obesity rate has galloped toward 40 percent, doctors, drug designers and dispirited dieters have all wondered the same thing: What if a pill could deliver the benefits of weight-loss surgery, but without the knife?

New research brings that hope a notch closer.

Scientists from the biotechnology company Amgen Inc. report they have identified and improved upon a naturally occurring protein that brought about significant changes in obese mice and monkeys, including weight loss and rapid

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