This wide ranging synthesis offers a new understanding of how energy causes and enables change. It places Newton's laws in a new, and broader perspective - throwing light on many current dilemmas. Working from an analysis of the energy transactions of systems, it develops a theory showing how the underlying energy transactions of systems shape all change. For example, system dynamics insights are used to examine Darwin's theory of evolution, which is currently in a crisis. The recent discovery that genetic information can flow not only from DNA to RNA, but also in reverse, provides a vital clue which challenges a key aspect of Darwin's theory of evolution. This new genetic research matches the analysis from system dynamics, of how energy determines change in living systems. Energy is the common basis for all endeavour - a fundamental link among the sciences and the social sciences.