When they were ten years old, the Dead End Boys—Ben, Rob, Mike, and Brian—witnessed a triple murder attempt by a notorious gangster known as “Slim Jimmy” near their home in Southern New Jersey. In the face of police questioning and fear of consequences from the Mafia, they learned at an early age that in order to protect themselves and their families, sometimes big secrets need to be kept. What’s more, the incident cemented the boys’ deep, lifelong bond.
Now in their twenties, the Dead End Boys decide to vacation in Miami, Florida, to get relief from the brutally cold winter in the northeast, maybe party a bit, and possibly meet some girls. But one morning, Ben awakes alone in an abandoned field with no recollection of what happened. He knows he must find his friends. The clues lead him to the Florida Keys, where the Dead End Boys have been set up to run drugs for the Cuban mafia that has its grip on Miami.
This group of young men, who learned to trust only each other at a young age, are about to put those lessons of loyalty to the test once more.