This audio program explores relapse prevention in pediatric depression and the risk of mania or hypomania for patients with bipolar depression taking an antidepressant without a mood stabilizer. The series on global mental health describes a man in Cambodia with seizures, anorexia, and depression. The issue covers adverse neuropsychiatric effects of glucocorticoid medications, the patient-therapist relationship in psychotherapy, and the outcomes of psychodynamic therapy and CBT in social anxiety disorder. Articles can be viewed online at www.ajp.psychiatryonline.org.