DRUG STUDY

GENERIC NAME
prochlorperazine

BRAND NAME
Compazine Spansule

CLASSIFICATION

MECHANISM OF ACTION
Blocks postsynaptic dopamine receptors in the brain ↓ Depresses the RAS ↓ Including parts of the brain ↓ With wakefulness and emesis

PATIENT DOSAGE
5 mg PO TID

CONTRAINDICATIONS

ADVERSE EFFECTS MANIFESTED BY THE CLIENT/ OBSERVED BASE ON DRUG HANDBOOK
● Autonomic: dry mouth, salivation, nasal congestion, nausea, vomiting, anorexia, fever, pallor, flushed faces, sweating, constipation, paralytic ileus, urinary retention, enuresis, male impotence.

NURSING INTERVENTION

anti-psychotic medication

Contraindicated with hypersensitivity to phenothiazine, coma or severe CNS depression, bone marrow depression, blood dyscrasia, circulatory collapse, subcortical brain damage, Parkinson’s disease, liver damage, coronary disease, severe hypotension or hypertension, and history of cardiac dysrhythmias.

● Assess patient’s history of Coma or severe CNS depression. ● Assess patient’s weight, reflexes, BP.

● Make sure that the client ● CNS: drowsiness, dizziness, will take the drug exactly as insomnia, vertigo, headache, prescribed by the physician. weakness, tremor, ataxia, slurring, cerebral edema, ● maintain patient’s fluid seizures. intake, and use precautions against heatstroke in hot ● CV: hypotension, orthostatic weather. hypotension, tachycardia, bradycardia, cardiac arrest, heart ● Make sure that the patient failure and cardiomegaly. will avoid exposure to ultraviolet or sunlight to ● HEMATOLOGIC: eosinophilia, prevent photosensitivity. leukopenia, leukocytosis, anemia, aplastic anemia, hemolytic ● ask the client to wear anemia, and pancytopenia. protective clothing. ● RESPIRATORY: bronchospasm, suppression of laryngospasm, dyspnea, suppression of cough reflex and potential for aspiration. ● ask the client to avoid dangerous activities.

● Report to the physician if the following occurs: fever, unusual bleeding, bruising, ●OTHER: Urine discoloration pink rash, weakness, tremors, to red brown. impaired vision, dark urine, pale stools. Yellowish

.discoloration of the skin or eyes.

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