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A.

actinomycemtemcomitans LPS, leukotoksin, Hsp60, fimbria, aktinobasilin, kolagenase

P. gingivalis Fimbria, hemaglutinin, LPS, antifagosit, proteinase, hemolisin, gingipain, kolagenase

T. forthyus Adhesin, LPS, gingipain, enzim proteolitik, neuraminidase

PENYAKIT PERIODONTAL

Infeksi fokal oral

A. actinomycemtemcomitans LPS, leukotoksin, Hsp60, fimbria, aktinobasilin, kolagenase

P. gingivalis Fimbria, hemaglutinin, LPS, antifagosit, proteinase, hemolisin, gingipain, kolagenase

T. forthyus Adhesin, LPS, gingipain, enzim proteolitik, neuraminidase

Collagen-like platelet aggregation

Fimbria

Lipopolisaka rida TLR-2 TLR-4 MCP-1

Enzim-enzim proteolitik CRP


Fibrinogen

Hsp60

Diet berubah karena hilangnya gigi

Paquette, et al.

PAR-1 PAR-4 Koagulasi


Brodala, et al.

Autoimun
Choi, et al.

NF-kB

Monosit Makrofage

Faktor risiko klasik


Joshipura, et al.

Pembuluh darah menebal


Rose, et al.

IL-1, IL-6, IL-8, IL-12, TNF- Oksidasi LDL


Blair, et al., Wada, et al.