LACTULOSE 1. Name & class of drug – generic and trade name.

GENERIC NAME: Lactulose BRAND NAME: Cephulac, Chronulac CLASSIFICATION: Gastrointestinal agent, hyperosmotic laxative 2. Dose range and routes for adult & geriatric client. PREPARATIONS: PO DOSING: 10mg/15ml solution, syrup 3. Purpose prescribed. Underline reason your client is prescribed drug. THERAPEUTIC EFFECTS: Acidifies colon contents, osmotic effect of organic acids causes laxative action USES: prevention and tx of portal-systemic encephalopathy (PSE), including stages of hepatic precoma and coma, and by prescription for relief of chronic constipation 4. Major side effects & drug interactions. DRUG INTERACTIONS: laxatives may incorrectly suggest therapeutic action of lactulose SIDE EFFECTS: diarrhea

5. Nursing Implications & teaching. • • • Effects are seen in 24-48 hrs Do not self medicate with another laxative because of slow onset Notify Dr if diarrhea persists for more than 24 hrs, could be a sign of overdose, and need for med adjustment