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LACTULOSE

1. Name & class of drug – generic and trade name.

GENERIC NAME: Lactulose


BRAND NAME: Cephulac, Chronulac

CLASSIFICATION: Gastrointestinal agent, hyperosmotic laxative

2. Dose range and routes for adult & geriatric client.

PREPARATIONS: PO

DOSING: 10mg/15ml solution, syrup

3. Purpose prescribed. Underline reason your client is prescribed drug.

THERAPEUTIC EFFECTS: Acidifies colon contents, osmotic effect of organic acids causes laxative action

USES: prevention and tx of portal-systemic encephalopathy (PSE), including stages of hepatic precoma and coma, and by
prescription for relief of chronic constipation

4. Major side effects & drug interactions.

DRUG INTERACTIONS: laxatives may incorrectly suggest therapeutic action of lactulose

SIDE EFFECTS: diarrhea


5. Nursing Implications & teaching.

• Effects are seen in 24-48 hrs


• Do not self medicate with another laxative because of slow onset
• Notify Dr if diarrhea persists for more than 24 hrs, could be a sign of overdose, and need for med adjustment