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DECADRON

1. Name & class of drug – generic and trade name.

GENERIC NAME: Dexamethasone acetate, dexamethasone sodium phosphate
BRAND NAME: Dalalone D. P., Decadron-LA, Decaject-LA, Dexacen LA-S, Dexone LA, Dexone LA, Solurex LA, AK-Dek,
Alba Dex, Decadrol,

CLASSIFICATION: Hormones and synthetic substitutes, adrenal corticosteroid, glucocorticosteiroid

2. Dose range and routes for adult & geriatric client.

PREPARATIONS: PO/IV/IM

DOSING: tablets – 0.25mg, 0.5 mg, 0.75 mg, 1 mg, 1.5 mg, 2 mg, 4 mg, 6 mg
Oral solution – 0.5 mg/5ml, 0.5 mg/0.5mg  *** I don’t understand this measurement, but it’s directly out of
the book
Topical aerosol – 0.01%, 0.04%
Injection suspension – 8mg/ml, 16mg/ml
Injection – 4mg/ml, 10mg/ml, 20mg/ml, 24mg/ml
Cream – 0.3%
Ophthalmic sol’n – 0.01%
Ophthalmic ung - 0.05%

3. Purpose prescribed. Underline reason your client is prescribed drug.

THERAPEUTIC EFFECTS: anti-inflammatory and immunosuppression properties

USES: inflammatory conditions, allergic states, collagen diseases, hematologic disorders, cerebral edema, addisonian shock,
palliative tx of neoplastic disease, adjunction short-term therapy in acute rheumatic disorders and GI diseases, diagnostic test
for Cushing’s syndrome, differential diagnosis of adrenal hyperplasia and adrenal adenoma.
4. Major side effects & drug interactions.

DRUG INTERACTIONS: Barbiturates increase steroid metabolism. Diuretics compound K+ loss. Ambenonium,
neostigmine, pyridostigmine may cause muscle weakness in pts with myasthenia gravis. May inhibit antibody response to
vaccines and toxoids.

SIDE EFFECTS: Nasal irritation (aerosol), edema (cv), hyperglycemia (endocrine), posterior subcapsular cataract (special
senses), oral candidiasis (GI), impaired wound healing (skin)

5. Nursing Implications & teaching.

• Watch for hypoadrenocorticism: lack of response to med, malaise, orthostatic hypotension, muscular weakness, pain,
N/V, anorexia, hypoglycemic reactions, mental depression
• Watch for hyperadrenocorticism: changes in appearance, easy bruising
• Hiccups that occur for several hours
• Evaluate electrolytes and bp at regular intervals
• Add K+ rich foods to diet
• Doses may need to be adjusted during periods of stress, inform Dr of changes in living condition
• D/C med gradually
• Prevent exposure to infection, trauma as drug is an immunosuppressor