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2 [PUBLISHED IN THE GAZETTE OF INDIA, No.19, PART III, SECTION 4] Ministry of Health and Family Welfare (Pharmacy Council of India) New Delhi, 10th May, 2008.
Pharm.D. Regulations 2008
Regulations framed under section 10 of the Pharmacy Act, 1948 (8 of 1948). (As approved by the Government of India, Ministry of Health vide, letter No.V.13013/1/2007-PMS, dated the 13th March, 2008 and notified by the Pharmacy Council of India). No.14-126/2007-PCI.― In exercise of the powers conferred by section 10 of the Pharmacy Act, 1948 (8 of 1948), the Pharmacy Council of India, with the approval of the Central Government, hereby makes the following regulations, namely:CHAPTER-I 1. Short title and commencement. – (1) These regulations may be called the Pharm.D. Regulations 2008. (2) They shall come into force from the date of their publication in the official Gazette. 2. Pharm.D. shall consist of a certificate, having passed the course of study and examination as prescribed in these regulations, for the purpose of registration as a pharmacist to practice the profession under the Pharmacy Act, 1948.
CHAPTER-II 3. Duration of the course. – a) Pharm.D: The duration of the course shall be six academic years (five years of study and one year of internship or residency) full time with each academic year spread over a period of not less than two hundred working days. The period of six years duration is divided into two phases – Phase I – consisting of First, Second, Third, Fourth and Fifth academic year. Phase II – consisting of internship or residency training during sixth year involving posting in speciality units. It is a phase of training wherein a student is exposed to actual pharmacy practice or clinical pharmacy services and acquires skill under supervision so that he or she may become capable of functioning independently. b) Pharm.D. (Post Baccalaureate): The duration of the course shall be for three academic years (two years of study and one year internship or residency) full time with each academic year spread over a period of not less than two hundred working days. The period of three years duration is divided into two phases – Phase I – consisting of First and Second academic year. Phase II – consisting of Internship or residency training during third year involving posting in speciality units. It is a phase of training wherein a student is exposed to actual pharmacy practice or clinical pharmacy services, and acquires skill under supervision so that he or she may become capable of functioning independently. 4. Minimum qualification for admission to. – a) Pharm.D. Part-I Course – A pass in any of the following examinations (1) 10+2 examination with Physics and Chemistry as compulsory subjects along with one of the following subjects: Mathematics or Biology. (2) A pass in D.Pharm course from an institution approved by the Pharmacy Council of India under section 12 of the Pharmacy Act. (3) Any other qualification approved by the Pharmacy Council of India as equivalent to any of the above examinations. Provided that a student should complete the age of 17 years on or before 31 st December of the year of admission to the course. Provided that there shall be reservation of seats for the students belonging to the Scheduled Castes, Scheduled Tribes and other Backward Classes in accordance with the instructions issued by the Central Government/State Government/Union Territory Administration as the case may be from time to time.
Institutions running B. (Post Baccalaureate) programme will be permitted only in those institutions which are permitted to run Pharm.No. (4) and (5) below. 6.4 1. devoted to each subject for its teaching in theory. of hours of Theory (2) (3) No.Pharm from an institution approved by the Pharmacy Council of India under section 12 of the Pharmacy Act: Provided that there shall be reservation of seats for the students belonging to the Scheduled Castes.2 1. of hours of Tutorial (5) (1) 1. programme.D.D.4 b) Pharm. – The course of study for Pharm. Course of study. Scheduled Tribes and other Backward Classes in accordance with the instructions issued by the Central Government/State Government/Union Territory Administration as the case may be from time to time.Pharm programme approved under section 12 of the Pharmacy Act.5 1. Name of Subject No.D.D. Pharm.D. programme. practical and tutorial shall not be less than that noted against it in columns (3). Programme – 30 students.D.D. TABLES First Year : S. The number of hours in a week. (Post Baccalaureate) Programme – 10 students.6 Human Anatomy and Physiology Pharmaceutics Medicinal Biochemistry Pharmaceutical Organic Chemistry Pharmaceutical Inorganic Chemistry Remedial Mathematics/ Biology Total hours 3 2 3 3 2 3 16 3 3 3 3 3 3* 18 1 1 1 1 1 1 6 = (40) * For Biology . of hours of Practical (4) No. shall include the subjects as given in the Tables below. 5. 7. will only be permitted to run Pharm. Number of admissions in the above said programmes shall be as prescribed by the Pharmacy Council of India from time to time and presently be restricted as below – i) Pharm. (Post Baccalaureate) Course A pass in B. ii) Pharm.1 1.3 1.
3 2.2 3.3 3. of hours of Tutorial (5) (1) 2.6 Pathophysiology Pharmaceutical Microbiology Pharmacognosy & Phytopharmaceuticals Pharmacology-I Community Pharmacy Pharmacotherapeutics-I Total Hours 3 3 3 3 2 3 17 3 3 3 9 1 1 1 1 1 1 6 = 32 Third Year: S. of hours of Tutorial (5) (1) 3.5 3.4 2.1 3.5 2.No Name of Subject No. of hours of Practical (4) No. of hours of Practical (4) No.5 Second Year: S.2 2. of hours of Theory (2) (3) No.1 2. Name of Subject No.No. of hours of Theory (2) (3) No.4 3.6 Pharmacology-II Pharmaceutical Analysis Pharmacotherapeutics-II Pharmaceutical Jurisprudence Medicinal Chemistry Pharmaceutical Formulations Total hours 3 3 3 2 3 2 16 3 3 3 3 3 15 1 1 1 1 1 5 = 36 .
4 4.6 Fourth Year: S. of hours of Tutorial (1) (2) (3) (5) 4.3 4.6 Pharmacotherapeutics-III Hospital Pharmacy Clinical Pharmacy Biostatistics & Research Methodology Biopharmaceutics & Pharmacokinetics Clinical Toxicology Total hours 3 2 3 2 3 2 15 3 3 3 3 12 1 1 1 1 1 1 6 = 33 Fifth Year: S.5 Clinical Research Pharmacoepidemiology and Pharmacoeconomics Clinical Pharmacokinetics & Pharmacotherapeutic Drug Monitoring Clerkship * Project work (Six Months) Total hours 3 3 2 8 20 20 1 1 1 1 4 = 32 * Attending ward rounds on daily basis. of hours of Practical/ Hospital Posting (4) No. Name of Subject No. .4 5. of hours of Seminar (5) (1) 5. of hours of Hospital posting* (4) No. of hours of Theory (2) (3) No.1 4. Name of Subject No. of hours of Theory No.1 5.2 5.3 5.No.2 4.No.5 4.
(3) The examinations shall be of written and practical (including oral nature) carrying maximum marks for each part of a subject as indicated in Tables below : TABLES First Year examination : S. – (1) No person. etc.6 Human Anatomy and Physiology Pharmaceutics Medicinal Biochemistry Pharmaceutical Organic Chemistry Pharmaceutical Inorganic Chemistry Remedial Mathematics/ Biology 70 70 70 70 70 70 Sessional 30 30 30 30 30 30 Total 100 100 100 100 100 100 600 Maximum marks for Practicals Examination 70 70 70 70 70 70* Sessional 30 30 30 30 30 30* Total 100 100 100 100 100 100* 600 = 1200 * for Biology.2 1. shall submit a scheme as prescribed by the Pharmacy Council of India.. society or university shall start and conduct Pharm. Student should independently provide the clinical pharmacy services to the allotted wards.. labs.No. Examination.5 1. (2) Any person or pharmacy college for the purpose of obtaining permission under sub-section (1) of section 12 of the Pharmacy Act. Syllabus. Approval of the authority conducting the course of study. nonteaching staff.D or Pharm. institution. – (1) Every year there shall be an examination to examine the students. equipments. (3) The scheme referred to in sub-regulation (2) above. as specified in Appendix-B to these regulations. teaching staff.7 Sixth Year: Internship or residency training including postings in speciality units. – The syllabus for each subject of study in the said Tables shall be as specified in Appendix -A to these regulations.1 1.3 1. accommodation. shall be in such form and contain such particulars and be preferred in such manner and be accompanied with such fee as may be prescribed: Provided that the Pharmacy Council of India shall not approve any institution under these regulations unless it provides adequate arrangements for teaching in regard to building. 10. . The first examination in a year shall be the annual examination and the second examination shall be supplementary examination. (Post Baccalaureate) programme without the prior approval of the Pharmacy Council of India. and (ii) Two months each in three other speciality departments 8.4 1. Name of Subject Maximum marks for Theory Examination 1.D. (2) Each examination may be held twice every year. (i) Six months in General Medicine department. 9.
1 3.6 Pharmacology-II Pharmaceutical Analysis Pharmacotherapeutics-II Pharmaceutical Jurisprudence Medicinal Chemistry Pharmaceutical Formulations 70 70 70 70 70 70 Sessional 30 30 30 30 30 30 Total 100 100 100 100 100 100 600 Maximum marks for Practicals Examination 70 70 70 70 70 Sessional 30 30 30 30 30 Total 100 100 100 100 100 500 = 1100 Fourth Year examination : S.6 Pathophysiology Pharmaceutical Microbiology Pharmacognosy & Phytopharmaceuticals Pharmacology-I Community Pharmacy Pharmacotherapeutics-I 70 70 70 70 70 70 Sessional 30 30 30 30 30 30 Total 100 100 100 100 100 100 600 Maximum marks for Practicals Examination 70 70 70 Sessional 30 30 30 Total 100 100 100 300 = 900 Third Year examination : S.1 2.4 4.2 3. Name of Subject Maximum marks for Theory Examination 2.3 3.4 3.5 2.2 4.No.1 4.3 4.2 2.3 2.8 Second Year examination : S.No.No. Name of Subject Maximum marks for Theory Examination 3.6 Pharmacotherapeutics-III Hospital Pharmacy Clinical Pharmacy Biostatistics & Research Methodology Biopharmaceutics & Pharmacokinetics Clinical Toxicology 70 70 70 70 70 70 Sessional 30 30 30 30 30 30 Total 100 100 100 100 100 100 600 Maximum marks for Practicals Examination 70 70 70 70 Sessional 30 30 30 30 Total 100 100 100 100 400 = 1000 .5 3. Name of Subject Maximum marks for Theory Examination 4.5 4.4 2.
D.D. (Post Baccalaureate) course. or as the case may be. . ** 30 marks – viva-voce (oral) 70 marks – Thesis work 11.9 Fifth Year examination : S. the Pharm.4 5. shall be maintained for each student in the institution and 30 marks for each theory and 30 marks for each practical subject shall be allotted as sessional. Award of sessional marks and maintenance of records. in proof of his or her having regularly and satisfactorily undergone the course of study by attending not less than 80% of the classes held both in theory and in practical separately in each subject shall be eligible for appearing at examination.3 Clinical Research Pharmacoepidemiology and Pharmacoeconomics Clinical Pharmacokinetics & Pharmacotherapeutic Drug Monitoring Clerkship * Project work (Six Months) 70 70 70 Sessional 30 30 30 Total 100 100 100 Maximum marks for Practicals Examination Sessional Total - 5. Pharm. (3) The sessional marks in practicals shall be allotted on the following basis:(i) Actual performance in the sessional examination (20 marks). (Post Baccalaureate) course.― (1) A regular record of both theory and practical class work and examinations conducted in an institution imparting training for Pharm. (3) Practical examination shall also consist of a viva –voce (Oral) examination. (4) Clerkship examination – Oral examination shall be conducted after the completion of clerkship of students. pharmaceutical care planning and knowledge of therapeutics shall be assessed.― Only such students who produce certificate from the Head of the Institution in which he or she has undergone the Pharm. An external and an internal examiner will evaluate the student. 12. etc. or as the case may be.D. promptness. Students’ capabilities in delivering clinical pharmacy services. (2) There shall be at least two periodic sessional examinations during each academic year and the highest aggregate of any two performances shall form the basis of calculating sessional marks. Name of Subject Maximum marks for Theory Examination 5. viva-voce record maintenance.5 - - 300 70 100** 30 - 100 100 200 = 500 * Attending ward rounds on daily basis. Eligibility for appearing Examination. (10 marks).D. Mode of examinations.1 5. (2) A Student who fails in theory or practical examination of a subject shall re-appear both in theory and practical of the same subject.― (1) Theory examination shall be of three hours and practical examination shall be of four hours duration.No.2 5. (ii) Day to day assessment in the practical class work. 13. Students may be asked to present the allotted medical cases followed by discussion.
1948. Internship. which shall be approved by the Pharmacy Council of India under sub-section (2) of section 12 of the Pharmacy Act. shall be granted a certificate by the examining authority.D.― (1) Internship is a phase of training wherein a student is expected to conduct actual practice of pharmacy and health care and acquires skills under the supervision so that he or she may become capable of functioning independently. (2) Every student has to undergo one year internship as per Appendix-C to these regulations.D. Eligibility for promotion to next year. or as the case may be. However. . Minimum marks for passing examination.― Examinations mentioned in regulations 10 to12 and 14 shall be held by the examining authority hereinafter referred to as the university. 17.― A student shall not be declared to have passed examination unless he or she secures at least 50% marks in each of the subjects separately in the theory examinations. The students securing 60% marks or above in aggregate in all subjects in a single attempt at the Pharm. (Post Baccalaureate) course examination shall be declared to have passed in first class.D. Approval of examinations.10 14. (Post Baccalaureate) (Doctor of Pharmacy) as the case may be.― All students who have appeared for all the subjects and passed the first year annual examination are eligible for promotion to the second year and. failure in more than two subjects shall debar him or her from promotion to the next year classes.― Every student who has passed the examinations for the Pharm. D. Certificate of passing examination. 15. 18. 16. including sessional marks and at least 50% marks in each of the practical examinations including sessional marks. Such approval shall be granted only if the examining authority concerned fulfills the conditions as specified in Appendix–D to these regulations. Students securing 75% marks or above in any subject or subjects shall be declared to have passed with distinction in the subject or those subjects provided he or she passes in all the subjects in a single attempt. so on. (Doctor of Pharmacy) or Pharm. Pharm.
Project work. analysis and reporting and interpretation skills. The same shall be announced to students within one month of commencement of the fifth year classes. one at middle and one at the end of the project work. In the fifth year. Methodology. Hospital posting. 20. one in the beginning. It shall be patient and treatment (Medicine) oriented. discussions and conclusions. like drug utilisation reviews.11 CHAPTER-III Practical training 19. (iv) project work shall be approved by the institutional ethics committee. a project work shall be carried out under the supervision of a teacher. 22. . and (ii) develop the students in data collection. methodology anticipated benefits and references shall be submitted to the Head of the Department or Head of the Institution. pharmacoepidemiology. The project topic must be approved by the Head of the Department or Head of the Institution. every student shall spend half a day in the morning hours attending ward rounds on daily basis as a part of clerkship. Theory teaching may be scheduled in the afternoon. (ii) project topic shall be approved by the Head of the Department or Head of the Institution.― (1) To allow the student to develop data collection and reporting skills in the area of community. Each student shall submit report duly certified by the preceptor and duly attested by the Head of the Department or Institution as prescribed.― Every student shall be posted in constituent hospital for a period of not less than fifty hours to be covered in not less than 200 working days in each of second. (iii)project work chosen shall be related to the pharmacy practice in community. third & fourth year course.― The main objectives of the project work is to― (i) show the evidence of having made accurate description of published work of others and of having recorded the findings in an impartial manner. hospital and clinical pharmacy. Project work shall be presented in a written report and as a seminar at the end of the year. (2) Project work shall comprise of objectives of the work. (v) student shall present at least three seminars. hospital and clinical setup. results. External and the internal examiners shall do the assessment of the project work. 21. namely:― (i) students shall work in groups of not less than two and not more than four under an authorised teacher. methodology. Objectives of project work. pharmacovigilance or pharmacoeconomics. and (vi) two-page write-up of the project indicating title.― To complete the project work following methodology shall be adopted. objectives.
The cover page of the project report shall contain details about the name of the student and the name of the authorised teacher with font size 14. Reporting . (ii) Students shall be evaluated in groups for four hours (i. the same shall be done based on item numbers b. about half an hour for a group of four students). Evaluation. (iii)Three seminars presented by students shall be evaluated for twenty marks each and the average of best two shall be forwarded to the university with marks of other subjects. (3) Submission of the project report shall be done at least one month prior to the commencement of annual or supplementary examination. (iv) Evaluation shall be done on the following items: Marks a) Write up of the seminar (7. Head of the Department as well as by the Head of the Institution (2) Project report shall be computer typed in double space using Times Roman font on A4 paper..12 23. Project report should include a certificate issued by the authorised teacher.5) c) Communication skills (7. sub-tiles in bold with font size 14 and the text with font size 12.5) (70 marks) Explanation.5) b) Presentation of work (7.5) (17.e.― For the purposes of differentiation in the evaluation in case of topic being the same for the group of students.5) (17.5) Total (30 marks) (v) Final evaluation of project work shall be done on the following items: a) Write up of the seminar b) Presentation of work c) Communication skills d) Question and answer skills Total Marks (17. c and d mentioned above. .5) (17.― (1) Student working on the project shall submit jointly to the Head of the Department or Head of the Institution a project report of about 40-50 pages. The title shall be in bold with font size 18. 24.5) d) Question and answer skills (7.― The following methodology shall be adopted for evaluating the project work― (i) Project work shall be evaluated by internal and external examiners.
Upon completion of the course the student shall be able to: a. K. Roger Warwick. SYLLABUS First Year 1. it enhances the understanding of how the drugs act on the various body systems in correcting the disease state of the organs. Publisher: Churchill Livingstone. pulse and Respiratory volumes. describe the various homeostatic mechanisms and their imbalances of various systems. C. b.J. 2. b. and Nicholas. c. and f. is used to correct the deviations in human body. /Week 1. b. London. describe the structure (gross and histology) and functions of various organs of the human body. Gray’s anatomy. Ross and Wilson’s foundations of anatomy and physiology. e. Principles of anatomy and physiology Publisher Harpercollins college New York. d. Physiology of human body. appreciate the interlinked mechanisms in the maintenance of normal functioning (homeostasis) of human body 3.W. identify the various tissues and organs of the different systems of the human body. Publisher: Holtsaunders. Human physiology. Since a medicament. It also helps in understanding both homeostasis mechanisms and homeostatic imbalances of various body systems.D. appreciate coordinated working pattern of different organs of each system. Volume 1&11.C.13 APPENDIX-A (See regulation 8) PHARM. c. Course materials: Text books a. Scope and Objectives: This course is designed to impart a fundamental knowledge on the structure and functions of the human body. which is produced by pharmacist. . Edinburg. Tortora Gerard J. P. Mary Dyson and Lawrence. d. Calcutta. Williams. Publisher: medical allied agency. Peter L. heart rate.C. Publisher:Churchill Livingstone. Wilson. H. perform the hematological tests and also record blood pressure. Guyton arthur.1 HUMAN ANATOMY & PHYSIOLOGY (THEORY) Theory : 3 Hrs. Reference books a. Chatterjee.
(done in practical classes . Hypotension.14 4. Congestive heart failure. and Definition of: Hypoxia. Types of movements of joints and disorders of joints (Definitions only) 5 Haemopoetic System a) Composition and functions of blood b) Haemopoesis and disorders of blood components (definition of disorder) c) Blood groups d) Clotting factors and mechanism e) Platelets and disorders of coagulation 6 Lymph a) Lymph and lymphatic system.6hrs) b) Classification of joints. 9 Digestive system a) Anatomy and physiology of GIT b) Anatomy and functions of accessory glands of GIT c) Digestion and absorption d) Disorders of GIT (definitions only) . Angina. Asphyxia. 3 Elementary tissues of the human body: epithelial. Disorders c) Disorders of lymphatic system (definition only) 7 Cardiovascular system a) Anatomy and functions of heart b) Blood vessels and circulation (Pulmonary. Dybarism. Muscular and nervous tissues-their sub-types and characteristics 4 a) Osseous system .structure. connective. Cardiac arrhythmias 8 Respiratory system a) Anatomy of respiratory organs and functions b) Mechanism / physiology of respiration and regulation of respiration c) Transport of respiratory gases d) Respiratory volumes and capacities. Arteriosclerosis. Atherosclerosis. basic terminologies used in this subject (Description of the body as such planes and terminologies) 2 Structure of cell – its components and their functions. composition. Myocardial infarction. coronary and systemic circulation) c) Electrocardiogram (ECG) d) Cardiac cycle and heart sounds e) Blood pressure – its maintenance and regulation f) Definition of the following disorders Hypertension. Oxygen therapy and resuscitation. Lecture wise program : Topics 1 Scope of anatomy and physiology. formation and circulation. composition and functions of the Skeleton. b) Spleen: structure and functions.
15 10 Nervous system a) Definition and classification of nervous system b) Anatomy. 11 Urinary system a) Anatomy and physiology of urinary system b) Formation of urine c) Renin Angiotensin system – Juxtaglomerular apparatus . Effect of athletic training on muscles and muscle performance. CVS in exercise. Body fluids and salts in exercise.acid base Balance d) Clearance tests and micturition 12 Endocrine system a) Pituitary gland b) Adrenal gland c) Thyroid and Parathyroid glands d) Pancreas and gonads 13 Reproductive system a) Male and female reproductive system b) Their hormones – Physiology of menstruation c) Spermatogenesis & Oogenesis d) Sex determination (genetic basis) e) Pregnancy and maintenance and parturition f) Contraceptive devices 14 Sense organs a) Eye b) Ear c) Skin d) Tongue & Nose 15 Skeletal muscles a) Histology b) Physiology of Muscle contraction c) Physiological properties of skeletal muscle and their disorders (definitions) 16 Sports physiology a) Muscles in exercise. physiology and functional areas of cerebrum c) Anatomy and physiology of cerebellum d) Anatomy and physiology of mid brain e) Thalamus. b) Respiration in exercise. hypothalamus and Basal Ganglia f) Spinal card: Structure & reflexes – mono-poly-planter g) Cranial nerves – names and functions h) ANS – Anatomy & functions of sympathetic & parasympathetic N. c) Drugs and athletics . Body heat in exercise.S.
Study of tissues of human body (a) Connective tissue. Determination of differential count of blood.S Shah Prakashan.P. latest edition. Latest edition. (b) Nervous tissue. 5. muslin cloth.C.B. Determination of R. models & specimens (a) Skeleton system part I-axial skeleton. 9. (d) Respiratory system. Publisher: NA List of Experiments: 1. Blood lancet. (b) Skeleton system part II. physiology and biochemistry. Course materials: Text books Goyal. Publisher: B. Latest edition. Ahmedabad. (c) Bleeding time & Clotting time. 6.1 HUMAN ANATOMY & PHYSIOLOGY (PRACTICAL) Practical : 3 Hrs. Determination of W. K. Determination of (a) Blood Pressure. 8. Laboratory Napkin. Practical anatomy. and Shah S. (b) Muscular tissue. Observation book(100pages). Reference books Ranade VG. R. 3. 7. (b) Hemoglobin content of Blood.A. 4. Natvar M. 2. Determination of (a) Erythrocyte Sedimentation Rate. Text book of practical physiology.appendicular skeleton. (c) Cardiovascular system. Stationary items. Study of tissues of human body (a) Epithelial tissue. . count of blood.C./Week General Requirements: Dissection box. Pune Anderson Experimental Physiology. (b) Blood group. Study of various systems with the help of charts. count of blood. record.16 1. Study of appliances used in hematological experiments.B. Publisher: PVG.
To record simple summation curve using gastroenemius sciatic nerve preparation. To record simple fatigue curve using gastroenemius sciatic nerve preparation. To record simple effect of temperature using gastroenemius sciatic nerve preparation. Study of appliances used in experimental physiology. To record simple muscle curve using gastroenemius sciatic nerve preparation. . Special senses. To record simple effect of load & after load using gastroenemius sciatic nerve preparation. 14. Reproductive system. promptness. viva-voce and record maintenance). 15. 13. Scheme of Practical Examination: Identification Synopsis Major Experiment Minor Experiment Viva Max Marks Duration Sessionals 04 04 07 03 02 20 03hrs Annual 10 10 20 15 15 70 04hrs Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity. 17. To perform pregnancy diagnosis test. 10. Nervous system. 12. 11. Urinary system. 16.17 (e) (f) (g) (h) (i) Digestive system. Study of different family planning appliances.
18 1. Scope and objectives: This course is designed to impart a fundamental knowledge on the art and science of formulating different dosage forms. 2. Calculations involving percentage solutions. Upon the completion of the course the student should be able to: a. 4. Extra pharmacopoeia and Indian national formulary. isotonic solutions etc. 3 Development of Indian Pharmacopoeia and introduction to other Pharmacopoeias such as BP. 4 Weights and measures. Introduction to Pharmaceutical dosage forms by Howard C.N. It prepares the students for most basics of the applied field of pharmacy. Preparation of simple.Schroff.classification and definitions b. and d. b. Calculation of children and infant doses. Insufflations. know the formulation aspects of different dosage forms. proof spirit. General Pharmacy by M. Lecture wise programme: Topics 1 a. Enemas and collodions. Throat paint. colorants.Sharma. compound powders. 5 Powders and Granules: Classification advantages and disadvantages. Ear drops. 2 Historical back ground and development of profession of pharmacy and pharmaceutical industry in brief. Ansel. appreciate the importance of good formulation for effectiveness.K. Posology: Definition. Factors affecting dose selection. .L. formulate different types of dosage forms. Study of Monophasic liquids like gargles.2 PHARMACEUTICS (THEORY) Theory : 2 Hrs. b. USP. Remington’s Pharmaceutical Sciences. Reference books a. Liniments and lotions. Register of General Pharmacy by Cooper and Gunn. c. mouth washes.Jain and S. Course materials: Text books a. do different pharmaceutical caluculation involved in formulation. Cooper and Gunns Dispensing for pharmacy students. Eutectic and Explosive powders. c. Introduction to dosage forms . allegation. /Week 1. A text book Professional Pharmacy by N. Nasal drops. parts and handling c. flavours with examples. Tooth powder and effervescent powders and granules. Prescription: definition. European Pharmacopoeia. Dusting powders. 3. b. d. 6 Monophasic Dosage forms: Theoretical aspects of formulation including adjuvant like stabilizers.
9 Galenicals: Definition. Syrup of Ephedrine Hcl NF c. classification and methods to overcome the incompatibilities. Orange Syrup 2. Strong solution of ferric chloride BPC c. Definition./Week List of Experiments: 1. Syrups a. stability and evaluation. 1. advantages and disadvantages. Strong solution of ammonium acetate IP . classification. Maceration and Percolation. sutures. Linctus a. 12 Incompatibilities: Introduction. equipment for different extraction processes like infusion. 8 Suppositories and pessaries: Definition. Solution of cresol with soap IP b. Simple Syrup I. Pediatric simple Linctus BPC 4. Piperizine citrate elixir BP b. Cascara elixir BPC c. tinctures and extracts. test for the type of emulsion. Syrup Vasaka IP d. Paracetamol elixir BPC 3. Displacement value and evaluation. Simple Linctus BPC b. methods of preparation of spirits.P b. 10 Pharmaceutical calculations. advantages and disadvantages. types of base. Decoction. method of preparation. formulation. ligatures and medicated bandages. Syrup of ferrous Phosphate IP e.2 PHARMACEUTICS (PRACTICAL) Practical : 3 Hrs. Solutions a. absorbable gelatin sponge. 11 Surgical aids: Surgical dressings. Aqueous Iodine Solution IP d. Strong solution of Iodine IP e.19 7 Biphasic dosage forms: Suspensions and emulsions. Elixir a.
Suspensions* a. Liquid paraffin emulsion 8. Insufflations 9. Boric acid suppositories b. Emulsions* a. viva-voce and record maintenance). . Mixtures with Physical b. butter paper and white paper required for dispensing. Liniments a. Eutectic powder b. Liniment of turpentine IP* b.20 5. Chloral suppositories 10. Chemical & Therapeutic incompatibilities * colourless bottles required for dispensing Paper envelope (white). Explosive powder c. Calamine lotion b. Liniment of camphor IP 6. Dusting powder d. Incompatibilities a. Magnesium Hydroxide mixture BP 7. Suppositories a. promptness. Scheme of Practical Examination: Synopsis Major Experiment Minor Experiment Viva Max Marks Duration Sessionals 05 10 03 02 20 03hrs Annual 15 25 15 15 70 04hrs Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity. Cod liver oil emulsion b. Powders a.
and prevention of diseases.21 1. Practical Biochemistry-Pattabhiraman. mutation and repair mechanism. Energy rich compounds. Scope of the Subject: Applied biochemistry deals with complete understanding of the molecular level of the chemical process associated with living cells. Text book of biochemistry – D. do. understand the genetic organization of mammalian genome.Ramarao c. /Week 1. know the metabolic process of biomolecules in health and illness (metabolic disorders). HMP shunt.Lehninger b. enzyme inhibition. Text book of biochemistry -. Text books (Theory) a.Plummer. glycogenesis. Enzyme action. Glycogenolysis.Alex kaplan &Laverve L.Martin b. Practical Biochemistry-David T. 3 Carbohydrate metabolism: Glycolysis. d. Text book of clinical chemistry. Objectives of the Subject (Know. Galactose tolerance test and their significance. Factor affecting enzyme activity. protein synthesis. Metabolic disorders of carbohydrate metabolism (diabetes mellitus and glycogen storage diseases). know the biochemical principles of organ function tests of kidney. 2. liver and endocrine gland. and e. appreciate) : The objective of the present course is providing biochemical facts and the principles to the students of pharmacy. . Nomenclature. Isoenzymes and their therapeutic and diagnostic applications. d.3 MEDICINAL BIOCHEMISTRY (THEORY) Theory : 3 Hrs. Lecture wise programme: Topics 1 Introduction to biochemistry: Cell and its biochemical organization. gluconeogenesis. ATP. c. Harpers review of biochemistry . Upon completion of the subject student shall be able to – a. Glucose. do the qualitative analysis and determination of biomolecules in the body fluids. Coenzymes and their biochemical role and deficiency diseases. Principles of biochemistry -. hormonal regulation of carbohydrate metabolism. understand the catalytic activity of enzymes and importance of isoenzymes in diagnosis of diseases. transport process across the cell membranes. Citric acid cycle (TCA cycle). 2 Enzymes: Definition. replication. IUB classification.Szabo Reference books (Theory) a. Cyclic AMP and their biological significance. control of treatment.Clinical chemistry deals with the study of chemical aspects of human life in health and illness and the application of chemical laboratory methods to diagnosis. b. 3.Satyanarayana c.
jaundice. and electrolyte distrubution. composition. Catabolism of Amino acids (Transamination. Determination of sodium. regulation and inhibition). Radio immuno assay (RIA) and Enzyme Linked Immuno Sorbent Assay (ELISA) 13 Electrolytes: Body water. 9 The kidney function tests: Role of kidney. Roll of the clinical chemistry laboratory. Defective metabolism of lipids (Atheroslerosis. d) Tests based upon abnormalities of serum proteins. Hormonal regulation of lipid metabolism. 11 Lipid profile tests: Lipoproteins. (stones) 10 Liver function tests: Physiological role of liver. excretory. inhibition of protein synthesis. 8 Introduction to clinical chemistry: Cell.) b) Test for NPN constituents. determination of blood and urine creatinine. LDL cholesterol and triglycerides. mutation and repair mechanism. chlorides. urea and uric acid) c) Urine concentration test d) Urinary tract calculi. hyperbilirubinemia. 7 Nucleic acid metabolism: Metabolism of purine and pyrimidine nucleotides. and urine urobilinogen. compartments. Electron transport chain (its mechanism in energy capture. nitrogen balance. urine bilirubin. c) Dye tests of excretory function. Genetic code.Serum bilirubin. 5 Biological oxidation: Coenzyme system involved in Biological oxidation. biosynthesis of fatty acids. 12 Immunochemical techniques for determination of hormone levels and protein levels in serum for endocrine diseases and infectious diseases. Determination of serum lipids. fatty liver. Metabolic disorder of Amino acids. functions. composition. porphoria.22 4 Lipid metabolism: Oxidation of saturated (-oxidation). Laboratory tests for normal function includesa) Urine analysis (macroscopic and physical examination. deamination & decarboxylation). DNA replication (semiconservative /onion peel models) and DNA repair mechanism. storage. water balance. metabolism of cholesterol. bicarbonates in the body fluids. hypercholesterolmiea). 6 Protein and amino acid metabolism: protein turn over. metabolic. (Creatinine /urea clearance. protective. circulatory functions and function in blood coagulation. b) Test for hepatic function test. quantitative and semiquantitative tests. Ketogenesis and ketolysis. production of bile pigments. calcium potassium. Selected enzyme tests. Oxidative phosphorylation. Protein synthesis. HDL cholesterol. total cholesterol. malfunction. . a) Test for hepatic dysfunction-Bile pigments metabolism. lipids. Urea cycle and its metabolic disorders. Uncouplers of ETC.
** 15 Determination of serum bilirubin** 16 Determination of Glucose by means of Glucoseoxidase. 5. (pH & Temp. Reference(s) shall be included at the end.** 18 Study of factors affecting Enzyme activity.* 9 Quantitative estimation of blood creatinine.** 12 Estimation of SGPT in serum.** 5 Quantitative estimation of urine creatinine by Jaffe’s method.* 3 Quantitative estimation of urine sugar by Benedict’s reagent method.** 8 Preparation of Folin Wu filtrate from blood. Time allocated for presentation may be 8+2 Min. It shall be computer draft copy.)** 19 Preparation of standard buffer solutions and its pH measurements (any two)* 20 Experiment on lipid profile tests** 21 Determination of sodium. promptness. Assignment can be a combined presentation at the end of the academic year.23 1.** 10 Quantitative estimation of blood sugar Folin-Wu tube method. 4.** 7 Quantitative estimation of serum cholesterol by Libermann Burchard’s method./Week Title of the Experiment: 1 Qualitative analysis of normal constituents of urine.** 14 Estimation of Proteins in Serum.* 2 Qualitative analysis of abnormal constituents of urine. 6. Minimum & Maximum number of pages.** 4 Quantitative estimation of urine chlorides by Volhard's method.** 11 Estimation of SGOT in serum.** 17 Enzymatic hydrolysis of Glycogen/Starch by Amylases.** 13 Estimation of Urea in Serum. Scheme of Practical Examination: Sessionals Annual Synopsis 05 15 Major Experiment 10 25 Minor Experiment 03 15 Viva 02 15 Max Marks 20 70 Duration 03hrs 04hrs Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity. 2. viva-voce and record maintenance).** ** indicate major experiments & * indicate minor experiments Assignments: Format of the assignment 1.3 MEDICINAL BIOCHEMISTRY (PRACTICAL) Practical : 3 Hrs. 3. . Name and signature of the student.calcium and potassium in serum.** 6 Quantitative estimation of urine calcium by precipitation method.
Alkyl Halides. relative reactivity and stability 4 Alicyclic compounds : Preparations of cyclo alkanes. c. Lecture wise programme : Topics 1 Structures and Physical properties: a.Jerry March.Brown c. Alkenes. Course materials: Text books a.P. Some important physical properties of organic compounds. Stereochemistry and steric hindrance. Solubility. I. protic and aprotic Solvents. carbocation and their stability. Organic chemistry – J.24 1. the fundamentals of chemistry Reference books a.P. free radical/ nucleophyllic / electrophyllic addition. role of solvents in SN1 reaction. Alcohols. Advanced organic chemistry. orientation of the reaction. . b. Organic chemistry. nucleophilic assistance by the solvents. Wiley d. Free radical/ nucleophyllic [alkyl/ acyl/ aryl] /electrophyllic substitution. Polarity of bonds.Cram and Hammered. 3 Free radicals chain reactions of alkane : Mechanism.Cram and D. Ketones. Ion dipole bonds. b. Organic chemistry. phase transfer catalysis. Boyd . M. Carboxylic Acid. Dienes. Pine Hendrickson 3. oxidation and reduction reactions with mechanism. stereochemistry. important medicinal uses of some important organic compounds. test for purity. Phenols. 2. kinetics of second and first order reaction. mechanism and kinetics of SN 2 reactions.Cram b. Acids and bases. role of solvents. Esters. polarity of molecules.M. /Week 1.Morrison and R. SN2 versus SN1 solvolyses. and e. B. d. Amines. Bentley and Driver-Text book of Pharmaceutical chemistry c. Acid Chlorides And Cycloalkanes. order of reactivity. Lowry bronsted and Lewis theories c.Organic chemistry.Finer. Bayer strain theory and orbital picture of angle strain. Methods of preparation. mechanism and kinetics of SN1 reactions. rearrangement of carbocation. stability of compounds. 5 Nuclophilic aliphatic substitution mechanism: Nucleophiles and leaving groups. principle involved in the assay.J. Inter molecular forces.Organic chemistry. elimination. Aldehydes. T. ion pairs. Some named organic reactions with mechanisms. Alkynes. Amides. IUPAC/Common system of nomenclature of simple organic compounds belonging to different classes of organic compounds. non ionic solutes and ionic solutes.L. Scope and objectives: This course is designed to impart a very good knowledge about a.4 PHARMACEUTICAL ORGANIC CHEMISTRY (THEORY) Theory : 3 Hrs. b.R. Isomerism 2 Nomenclature of organic compound belonging to the following classes Alkanes.
side chain halogination of alkyl benzene.2-versus 1. cyclo addition reactions. friedel craft alkylation. evidence for E2 mechanism. orientation of elimination. heat of hydrogenation and stability of alkenes. determination of relative reactivity. mechanism of nitration.addition. acid catalysis. hyper conjugation. orientation. free radical substitution in alkenes. 9 Theory of resonance: Allyl radical as a resonance hybrid. activating and deactivating O. 7 Electrophillic and free radicals addition: Reactions at carbon-carbon. classification of substituent group. amide and anhydride. determination of orientation. E2 and E1 mechanism. allyl cation as a resonance hybrid. effect of halogen on electrophilic aromatic substitution in alkyl benzene.25 6 Dehydro halogenation of alkyl halides: 1. stability. 11 Nucleophilic addition reaction: Mechanism. rate versus equilibrium. orientation of free addition. kinetics. reversibility. orientation and reactivity. addition of hydrogen bromides. absence of hydrogen exchange. absence hydrogen exchange. effect of substituent on acidity. nucleophilic acyl substitution reaction. orbital picture. addition of hydrogen halides. SN1 reactivity. markownikoff rule. double bond. SN2 nucleophilic substituion in vinylic substrate. acidity of acids. resonance stabilisation of allyl cation. comparision of free radical substitution with free radical addition. resonance stabilization of benzyl radical. 8 Carbon-carbon double bond as substituents: Free radical halogenations of alkenes. addition of halogen. peroxide effect. ionisation of carboxylic acids. 1. electrophile. mechanism of peroxide initiated addition of hydrogen bromide. electrophillic addition. conversion of acid to acid chloride. vinylic cation. additions of carbene to alkene. elimination versus substitution. mechanism of free radicals additon. sulphonation. resonance stabilisation of allyl radicals. acidity constants. allylic rearrangement. rearrangement.4-addition. hyper conjugation. dehydration of alcohol. friedel craft acylation. electrophilic addition to conjugated dienes. hyper conjugation. esters. ease of formation of conjugated dienes. orientation and reactivity of free radical addition to conjugated dienes.2 elimination. orientation and reactivity. halogenation. elimination via carbocation. 10 Elecrophilic aromatic substitution: Effect of substituent groups. stability of conjugated dienes. ease of dehydration. structure of carboxylate ions. hydrogenation. allylic rearrangements. mechanism. absence of rearrangement isotope effect. orientation and reactivity. E2 versus E1. nucleophilic substitution in allylic substrate. 1. comparison of alkyl nucleophilic substitution with acyl nucleophilic substitution. halohydin formation. the element effect. reactivity and orientation. . resonance in alkenes. nucleophyllic substitution in allylic substrate. mechanism. Role of caboxyl group.M directing groups.P. electron release via resonance.4.
Introduction to the various laboratory techniques through demonstration involving synthesis of the following compounds (at least 8 compounds to be synthesised): 1. Glyceryl trinitrate. Reformatsky reaction. Ethylene diamine dihyrate. benzyl benzoate. saccharin sodium. 16 Study of the following official compounds. assay and medicinal uses of Chlorbutol. comparison of aliphatic nucleophilic substitution with that of aromatic. test for purity. Kolbe reaction. acidity of phenols. Paraldehyde. Preparation of O-chlorobenzoic acid from O-chlorotolune 14. Fries rearrangement. perkin condensation. Benzoic acid / salicylic acid (Hydrolysis of ester) 7. Preparation of picric acid 13. Preparation of cyclohexanone from cyclohexanol . citric acid. Dibenzylidene acetone (Condensation) 5. Sandmeyer’s reaction. M-phenylene diamine (Reduction of M-dinitrobenzene) / Aniline from nitrobenzene 10. ethyl benzoate. Michael addition./Week I. dimethyl pthalate. Williamson synthesis. Benzanilide / Phenyl benzoate (Benzoylation) 3.6 – tribromo aniline (Bromination) 4. Vanillin. crossed cannizzaro reaction.26 12 Mechanism of aldol condensation. salicylic acid. 1-Phenylazo-2-napthol (Diazotisation and coupling) 6. aspirin. M-dinitro benzene (Nitration) 8. 14 Nucleophilic aromatic substitution: Bimolecular displacement mechanisms. Nitration of salicylic acid 12. Ethylene chloride. 10 – Antharaquinone (Oxidation of anthracene) / preparation of benzoic acid from toluene or benzaldehyde 9. Knoevenagel.4. sodium lauryl sulphate. benzoin condensation.4 PHARMACEUTICAL ORGANIC CHEMISTRY (PRACTICAL) Practical : 3 Hrs. Benzophenone oxime 11. Reimer tieman’s reactions.preparation. 9. Lactic acid. mephensin. basicity of amines. claisen condensation. 13 Hoffman rearrangement: Migration to electron deficient nitrogen. methyl salicylate. crossed aldol condensation. diazotisation and coupling. 15 Oxidation reduction reaction. orientation. Urea. P-bromo acetanilide / 2. cannizzaro reaction. Dimercaprol. Acetanilde / aspirin (Acetylation) 2. Wittig reaction. Tartaric acid. 1.
carboxylic acids. Alcohols. aldehyde and ketones. amides. anilides. amines. Ethylene. carbohydrates. esters. Scheme of Practical Examination: Sessionals Synopsis 05 Major Experiment 10 Minor Experiment 03 Viva 02 Max Marks 20 Duration 03hrs Annual 15 25 15 15 70 04hrs Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity. Cis alkene. hydrocarbons. Trans alkene. Identification of organic compounds belonging to the following classes by : Systematic qualitative organic analysis including preparation of derivatives Phenols. Ethane.27 II. inversion of configuration. . Acetylene. promptness. III. Introduction to the use of stereo models: Methane. viva-voce and record maintenance). nitrocompounds.
B. Stanlake’s Practical Pharmaceutical chemistry Vol-I & Vol-II c. and c. A.P. Upon completion of the course student shall be able to: a. Pharmaceutical Inorganic chemistry by Dr. of India. Course materials: Text books a.1985 and 1996. Scope and objectives: This course mainly deals with fundamentals of Analytical chemistry and also the study of inorganic pharmaceuticals regarding their monographs and also the course deals with basic knowledge of analysis of various pharmaceuticals.5 PHARMACEUTICAL INORGANIC CHEMISTRY (THEORY) Theory : 2 Hrs. Beckett and J. Lecture wise programme: Topics 1 Errors 2 Volumetric analysis 3 Acid-base titrations 4 Redox titrations 5 Non aqueous titrations 6 Precipitation titrations 7 Complexometric titrations 8 Theory of indicators 9 Gravimetry 10 Limit tests 11 Medicinal gases 12 Acidifiers 13 Antacids 14 Cathartics 15 Electrolyte replenishers . 3.Nagavi c.28 1.G. /Week 1. Analytical chemistry principles by John H. appreciate the importance of inorganic pharmaceuticals in preventing and curing the disease. b. A text book Inorganic medicinal chemistry by Surendra N.B. 2. Pandeya b. under stand the principles and procedures of analysis of drugs and also regarding the application of inorganic pharmaceuticals. Inorganic Pharmaceutical Chemistry by Anand & Chetwal b. Ministry of health 4. I. Govt.Gundu Rao Reference books a. Kennedy d. know the analysis of the inorganic pharmaceuticals their applications. H. Inorganic Pharmaceutical Chemistry III-Edition P.
Hydrogen peroxide – Permanganometry f. Limit test for arsenic f. Limit test (6 exercises) a.5 PHARMACEUTICAL INORGANIC CHEMISTRY (PRACTICAL) Practical : 3 Hrs. Calcilugluconate. Sodium hydroxide and sodium carbonate b. Limit test for iron d. Sodium chloride – Modified volhard’s method h. Ferrous sulphate. Copper sulpahte. Limit test for chlorides b. Test for identity (Any three exercises) a. Potassium chloride ./Week 1. Modified limit tests for chlorides and sulphates 2.Iodometry d.Cerimetry c. Barium sulphate c. Limit test for heavy metals e. Limit test for sulphates c. Sodium antimony gluconate or antimony potassium tartarate 3. Ammonium chloride. Oxalic acid and sodium oxalate 4. Sodium benzoate – Nonaqueous titration g.Complexometry e. Assays (10 exercises) a.29 16 17 18 19 20 21 Essential Trace elements Antimicrobials Pharmaceutical aids Dental Products Miscellaneous compounds Radio Pharmaceuticals 1. Ferrous sulphate d.Acid-base titration b. Boric acid and Borax c. Estimation of mixture (Any two exercises) a. Gravimetric estimation of barium as barium sulphate j. Sodium bicorbonate b. Assay of KI – KIO3 titration i.
Ammonium salts in potash alum d. Test for purity (Any two exercises) a. Calcium lactate d. promptness. Swelling power in Bentonite b. Presence of Iodates in KI 6. . Boric acids b. Magnesium suphate Scheme of Practical Examination : Sessionals Synopsis 05 Major Experiment 10 Minor Experiment1&2 03 Viva 02 Max Marks 20 Duration 03hrs Annual 15 25 15 15 70 04hrs Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity. Adsorption power heavy Kaolin e. viva-voce and record maintenance). Acid neutralising capacity in aluminium hydroxide gel c. Preparations (Any two exercises) a. Potash alum c.30 5.
Know Trignometry. differential equation with constant coefficient. Course materials: Text books a. differential equations. order. Successive differentiation.M. . Straight line. Product. 6 Differential equations: Definition. 7 Laplace transform: Definition. Trigonometry Part-I By S. Integral calculus By Shanthinarayan b. integral calculus. solve the problems of different types by applying theory. This subjects deals with the introduction to matrices. exponential. heterogeneous. Differential calculus.Grewal c. simultaneous linear equation of second order. Properties of linearity and shifting. degree. 3. Scope and objectives: This is an introductory course in mathematics. and c. Euler’s theorem on homogeneous functions of two variables 5 Integral Calculus: Definite integrals.6 REMEDIAL MATHEMATICS/BIOLOGY (THEORY) Theory : 3 Hrs. b. circle. integration by substitution and by parts. Laplace transform and their applications.Loney 4. Linear. Matrices. variable separable. Quotient Composite. Analytical geometry.B. laplace transform. /Week REMEDIAL MATHEMATICS : 1. differential calculus. solution of triangles 3 Analytical Geometry :Points.Sreenivas Reference books a. Differential equation. Text book of Mathematics for second year pre-university by Prof. appreciate the important applications of mathematics in pharmacy. Upon completion of the course the student shall be able to : – a.L. 2. Parametric. Properties of definite integrals. Lecture wise programme : Topics 1 Algebra : Determinants. Laplace transform of elementary functions. Determinant. Partial differentiation. analytical geometry. determinants. trigonometric and Logarithmic function. Integration. Differentiation of a sum.S. Matrices 2 Trigonometry : Sides and angles of a triangle. Differential calculus By Shantinarayan b. homogeneous.31 1. parabola 4 Differential calculus: Limit of a function. Leibnitz’s theorem. linear. trigonometry. Engineering mathematics By B.
Yeast. Reference books a.B. Aves Genearal organization of mammals Study of poisonous animals .Kokate. Stem. 2. distribution and the characters of the plants and animals. Scope and objectives: This is an introductory course in Biology. e. A manual for pharmaceutical biology practical by S.K. Raptiles.Dutta. which gives detailed study of natural sources such as plant and animal origin.Sreenivasa Naidu b. This subject gives basic foundation to Pharmacognosy. A Text book of Biology by Dr. Text book of Biology by S. Solanaceae.Gokhale and C.N. classification.Ananthakrishnan. Lilliaceae. Outlines of Zoology by M. Rubiaceae 11 Study of Fungi. A Text book of Biology by Naidu and Murthy c. This subject has been introduces to the pharmacy course in order to make the student aware of various naturally occurring drugs and its history. umbelliferae.Ekambaranatha ayyer and T.Gokhale b.32 BIOLOGY : 1. Botany for Degree students By A. sources. Course materials: Text books a. A Text book of Biology by B. Zinziberaceae.Thulajappa and Dr. Lecture wise programme : Topic PART – A 01 Introduction 02 General organization of plants and its inclusions 03 Plant tissues 04 Plant kingdom and its classification 05 Morphology of plants 06 Root.V. Penicillin and Bacteria 01 02 03 04 05 06 PART-B Study of Animal cell Study animal tissues Detailed study of frog Study of Pisces. Leaf and Its modifications 07 Inflorescence and Pollination of flowers 08 Morphology of fruits and seeds 09 Plant physiology 10 Taxonomy of Leguminosae.B. 3. Seetaram.C. d.
Study of Root modifications 5. Simple plant physiological experiments 10. Podophyllum.33 1. Cassia. T. viva-voce and record maintenance. Preparation of Permanent slides 8. Introduction of biology experiments 2. Computer based tutorials Scheme of Practical Examination : Identification Synopsis Major Experiment Minor Experiment Viva Max Marks Duration Sessionals 04 04 07 03 02 20 03hrs Annual 10 10 20 15 15 70 04hrs Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity. of Senna. . Study of cell wall constituents and cell inclusions 3. promptness. 9. Ephedra.6 BIOLOGY (PRACTICAL) Practical : 3 Hrs. Identification of animals 11. Study of Leaf modifications 6./Week Title: 1. Study of Stem modifications 4.S. Detailed study of Frog 12. Identification of Fruits and seeds 7.
Pathologic basis of disease by. Second edition.34 Second year 2. mechanism of autoimmunity. Text book of Pathology. Hence it will not only help to study the syllabus of pathology. Roger Walker. Clinical Pharmacy and Therapeutics. Text book of Pathology. Objectives of the Subject : Upon completion of the subject student shall be able to – a. describe the etiology and pathogenesis of the selected disease states. Detailed syllabus and lecture wise schedule : Chapter 1 Basic principles of cell injury and Adaptation a) Causes.Hypersensitivity Hypersensitivity type I. chemicals and drugs .1 PATHOPHYSIOLOGY (THEORY) Theory : 3 Hrs. transplantation antigens. Allergy due to food.Cotran. Churchill Livingstone publication 3. Text books (Theory) a. III. allograft rejections. Pathogenesis and morphology of cell injury b) Abnormalities in lipoproteinaemia. but also to get baseline knowledge of its application in other subject of pharmacy. name the signs and symptoms of the diseases. IV. mention the complications of the diseases.Y. 2.Autoimmunity Criteria for autoimmunity.Harsh Mohan c. /Week 1. and c. Robbins b.Acquired immune deficiency syndrome (AIDS) 3 . Transplantation and immunologic tolerance. Kumar. factors influencing healing of wounds Diseases of Immunity a) Introduction to Tand B cells b) MHC proteins or transplantation antigens c) Immune tolerance . Chemical mediators in inflammation. mechanism of rejection of allograft. glycogen infiltration and glycogen infiltration and glycogen infiltration and glycogen storage diseases 2 Inflammation a) Pathogenesis of acute inflammation. b. Types of chronic inflammation b) Repairs of wounds in the skin. Bhinde Reference books (Theory) a.M. Classifications of autoimmune diseases in man. Scope of the Subject: This course is designed to impart a thorough knowledge of the relevant aspects of pathology of various conditions with reference to its pharmacological applications. and understanding of basic Pathophysiological mechanisms. . Biological significance. II.
infective hepatitis. Cirrhosis and Alcoholic liver diseases j. Assignments : Title of the Experiment 1 Chemical Mediators of inflammation 2 Drug Hypersensitivity 3 Cigarette smoking & its ill effects 4 Biological Effects of Radiation 5 Etiology and hazards of obesity 6 Complications of diabetes 7 Diagnosis of cancer 8 Disorders of vitamins 9 Methods in Pathology-Laboratory values of clinical significance 10 Pathophysiology of Dengue Hemorrhagic Fever (DHF) Format of the assignment 1 Minimum & Maximum number of pages. general biology of tumors. Histological diagnosis of malignancy. Tuberculosis. Stroke (ischaemic and hemorrhage) f. spread of malignant tumors. Hypertension. Leprosy. Schizophrenia c. vitamins. e. CCF. Hepatitis. 5. classification of tumors. Time allocated for presentation may be 8+2 Min. .35 . mechanisms.Syphilis.NO. Angina. 2. 3. Atherosclerosis. It shall be computer draft copy. Asthma and chronic obstructive airway diseases Infectious diseases : Sexually transmitted diseases (HIV.SO2. stages and management Biological effects of radiation Environmental and nutritional diseases i) Air pollution and smoking. Myocardial infarction g. Depression and mania d. Name and signature of the student 6. and CO ii) Protein calorie malnutrition. Urinary tract infections. Diabetes Mellitus h. Types of shock. pathogenesis of starvation. Assignment can be a combined presentation at the end of the academic year 4. Peptic ulcer and inflammatory bowel diseases i. Acute and chronic renal failure k. patterns of spread. invasions and metastasis. 5 6 7 8 9 4.Amylodosis 4 Cancer: differences between benign and malignant tumors. etiology and pathogenesis of cancer. Pneumonia. disturbances of growth of cells. Typhoid. Reference(s) shall be included at the end. Malaria Dysentery (bacterial and amoebic ). obesity.Gonorrhea). Pathophysiology of common diseases a. NO2. Parkinsonism b.
Year book inc St. d. 1996. Saunders.‖2 nd edition WMC Brown Publishers. Objectives of the Subject : Upon completion of the subject student shall be able to – a. ― Immunology‖3 rd edition 1996. media etc.A. e. Jonathan Brostoff. 1996 Mosby. equipment. c. Jarley G. do cultivation and identification of the microorganisms in the laboratory. and treatment aspect.A ―Microbiology‖ 2nd. which is expected to change the complete drug product scenario in the future. The course further discusses the immunological preparations.edition Mc Graw Hill Company Inc b. B-3 Ansari road Darya ganj N. Text books (Theory) a. Reference books (Theory) a.2 PHARMACEUTICAL MICROBIOLOGY (THEORY) Theory : 3 Hrs. Vanitha Kale and Kishor Bhusari ― Applied Microbiology ‖ Himalaya Publishing house Mumbai. diseases its transmission. This course deals with the various aspects of microorganisms. know the anatomy. do identification of diseases by performing the diagnostic tests. diagnosis. Delhi. b. laboratory cultivation identification and maintenance. This is because of the relevance of microbiology to pharmaceutical sciences and more specifically to pharmaceutical industry. Oxford. morphology.‖Bentley’s Text Book of Pharmaceutics‖ B ailliere Tindals 24-28 London 1988 c. c. London. control and immunological tests.P Klein D.P. Rawlins E. know the mode of transmission of disease causing microorganism. Prescott L. Govt of India. and f.B. identification. Jarley G. Scope of the Subject: Microbiology has always been an essential component of pharmacy curriculum. Forbisher ― Fundamentals of Microbiology‖ Philidelphia W. 2. d. Mary Louis Turgeon ― Immunology and Serology in Laboratory Medicines‖ 2 nd edition. do estimation of RNA and DNA and there by identifying the source.36 2. Its also discusses with sterilization of pharmaceutical products.M. ― Microbiology. Prescot L. Mosbyyear book Europe Ltd. .M. b. Louis Missouri 63146. 1998. /Week 1. Klein.A.. appreciate the behavior of motility and behavioral characteristics of microorganisms. Harsh Mohan. symptoms of disease. War Roitt. ― Text book of Pathology‖ 3rd edition. Pharmaceutical biotechnology is the logical extension of pharmaceutical microbiology.. growth factors and sterilization of microorganisms. f. its classification.D. 1993 e. Pharmacopoeia of India. David male.
Study of malarial parasite. Classification. Study of different important media required for the growth of aerobic and anaerobic bacteria & fungi. Gram’s staining . . Significance of toxoids in active immunity. 3 Nutritional requirements. 4 Different methods used in isolation and identification of bacteria with emphasis to different staining techniques and biochemical reactions. Immunization programme. 5 Detailed study of different methods of sterilization including their merits and demerits. 10 Study of infectious diseases: Typhoid. . 8 Diagnostic tests : Schick’s Test. Hepatitis. 7 Immunology. 5 Enumeration of micro-organisms (Total and Viable)* 6 Study of the methods of isolation of pure culture. Detailed syllabus and lecture wise schedule : Title of the topic 1 Introduction to the science of microbiology. virus. Standardisation of vaccines and sera. Southern Blot PCR Widal.Study of disinfectants. Counting of bacteria -Total and Viable counting techniques. chemical nature of antigens structure and formation of Antibodies. acquired immunity( active and passive ) . General principles of natural immunity. 2 Different methods of classification of microbes and study of Bacteria. Fungi./Week Title of the Experiment: 1 Study of apparatus used in experimental microbiology*. enriched media and selective media. Elisa test. Definition. 6 Disinfectants. growth and cultivation of bacteria and virus. Tuberculosis. Mantaux Peripheral smear. virucidal activities. Antigen-Antibody reactions. bacteristatic. Negative staining** 4 Study of motility characters*.Immunity. 2. Syphilis & Gonorrhea and HIV. Differential media. Western Blot test. Sterilization methods for all pharmaceutical products. microbiological assay of Penicillin. 2 Sterilisation of glass ware’s. Phagocytosis.2 PHARMACEUTICAL MICROBIOLOGY (PRACTICAL) Practical : 3 Hrs. maintenance of lab cultures. Spirochetes. Major divisions of microbial world and Relationship among them. and importance of booster dose. 9 Microbial culture sensitivity Testing: Interpretation of results Principles and methods of different microbiological assays. QBC. Bacterial exotoxins and endotoxins. Preparation of media and sterilisation. antiseptics. Rickettsiae. Malaria. Meningitis.* 7 Bio chemical testing for the identification of micro*-organisms. Brief information on Validation. Cholera. Antigens.37 3.* 3 Staining techniques – Simple staining . Detailed study of sterility testing of different pharmaceutical preparations . Evaluation of bactericidal. Streptomycin and vitamin B2 and B12. evaluation of preservatives in pharmaceutical preparations. fungicidal and virucidal agents factors affecting their activation and mechanism of action.
Widal. 6. Reference(s) shall be included at the end. 3. Report of recent microbial techniques developed in diagnosing some common diseases. Scheme of Practical Examination: Synopsis Major Experiment Minor Experiment Viva Max Marks Duration Sessionals 05 10 03 02 20 03hrs Annual 15 25 15 15 70 04hrs Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity. 4. 5. malarial parasite. viva-voce and record maintenance). 2.** 14 Diagnostic tests for some common diseases. Assignment can be a combined presentation at the end of the academic year. It shall be computer draft copy. Latest advancement developed in identifying. 3. Name and signature of the student. promptness. . Minimum & Maximum number of pages. cultivating & handling of microorganisms. 2.* 10 Determination of minimum inhibitory concentration. Format of the assignment: 1.38 8 Cultural sensitivity testing for some micro-organisms.** * Indicate minor experiment & ** indicate major experiment Assignments: 1 Visit to some pathological laboratories & study the activities and equipment/instruments used and reporting the same. b. Visit to milk dairies (Pasturization) and microbial laboratories(other sterization methods) & study the activities and equipment/instruments used and reporting the same. Library assignments a.* 11 Microbiological assay of antibiotics by cup plate method.* 12 Microbiological assay of vitamins by Turbidometric method** 13 Determination of RWC. Time allocated for presentation may be 8+2 Min.* 9 Sterility testing for powders and liquids.
2.3 PHARMACOGNOSY & PHYTOPHARMACEUTICALS (THEORY)
Theory : 3 Hrs. /Week 1. Scope and objectives: This subject has been introduced for the pharmacy course in order to make the student aware of medicinal uses of various naturally occurring drugs its history, sources, distribution, method of cultivation, active constituents, medicinal uses, identification tests, preservation methods, substitutes and adulterants. 2. Upon completion of the course student shall be able to: a. under stand the basic principles of cultivation, collection and storage of crude drugs; b. know the source, active constituents and uses of crude drugs; and c. appreciate the applications of primary and secondary metabolites of the plant. 3. Course materials: Text books a. Pharmacognosy by G.E. Trease & W.C.Evans. b. Pharmacognosy by C.K.Kokate,Gokhale & A.C.Purohit. Reference books a. Pharmacognosy by Brady &Tyler.E. b. Pharmacognosy by T.E.Wallis. c. Pharmacognosy by C.S. Shah & Qadery. d. Pharmacognosy by M.A. Iyengar. 4. Lecture wise programme: Topics 1 Introduction. 2 Definition, history and scope of Pharmacognosy. 3 Classification of crude drugs. 4 Cultivation, collection, processing and storage of crude drugs. 5 Detailed method of cultivation of crude drugs. 6 Study of cell wall constituents and cell inclusions. 7 Microscopical and powder Microscopical study of crude drugs. 8 Study of natural pesticides. 9 Detailed study of various cell constituents. 10 Carbohydrates and related products. 11 Detailed study carbohydrates containing drugs.(11 drugs) 12 Definition sources, method extraction, chemistry and method of analysis of lipids. 13 Detailed study of oils. 14 Definition, classification, chemistry and method of analysis of protein. 15 Study of plants fibers used in surgical dressings and related products. 16 Different methods of adulteration of crude drugs.
2.3 PHARMACOGNOSY & PHYTOPHARMACEUTICALS (PRACTICAL)
Practical : 3 Hrs./Week General Requirements: Laboratory Napkin, Observation Book 150 pages Zero brush, Needle, Blade, Match box. List of experiments: 1 Introduction of Pharmacognosy laboratory and experiments. 2 Study of cell wall constituents and cell inclusions. 3 Macro, powder and microscopic study of Datura. 4 Macro, powder and microscopic study of Senna. 5 Macro, powder and microscopic study of Cassia.cinnamon. 6 Macro, powder and microscopic study of Cinchona. 7 Macro, powder and microscopic study of Ephedra. 8 Macro, powder and microscopic study of Quassia. 9 Macro, powder and microscopic study of Clove 10 Macro, powder and microscopic study of Fennel. 11 Macro, powder and microscopic study of Coriander. 12 Macro, powder and microscopic study of Isapgol. 13 Macro, powder and microscopic study of Nux vomica. 14 Macro, powder and microscopic study of Rauwolfia. 15 Macro, powder and microscopic study of Liquorice. 16 Macro, powder and microscopic study of Ginger. 17 Macro, powder and microscopic study of Podophyllum. 18 Determination of Iodine value. 19 Determination of Saponification value and unsaponifiable matter. 20 Determination of ester value. 21 Determination of Acid value. 22 Chemical tests for Acacia. 23 Chemical tests for Tragacanth. 24 Chemical tests for Agar. 25 Chemical tests for Starch. 26 Chemical tests for Lipids.(castor oil,sesame oil, shark liver oil,bees wax) 27 Chemical tests for Gelatin. Scheme of Practical Examination: Sessionals Annual Identification 04 10 Synopsis 04 10 Major Experiment 07 20 Minor Experiment 03 15 Viva 02 15 Max Marks 20 70 Duration 03hrs 04hrs Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity, promptness, viva-voce and record maintenance.
2.4 PHARMACOLOGY – I (THEORY)
Theory : 3 Hrs. /Week 1. Scope of the Subject: This subject will provide an opportunity for the student to learn about the drug with regard to classification, pharmacodynamic and pharmacokinetic aspects, adverse effects, uses, dose, route of administration, precautions, contraindications and interaction with other drugs. In this subject, apart from general pharmacology, drugs acting on autonomic nervous system, cardiovascular system, central nervous system, blood and blood forming agents and renal system will be taught. In addition to theoretical knowledge, the basic practical knowledge relevant to therapeutics will be imparted. 2. Objectives of the Subject : Upon completion of the subject student shall be able to (Know, do, appreciate) – a. understand the pharmacological aspects of drugs falling under the above mentioned chapters; b. handle and carry out the animal experiments; c. appreciate the importance of pharmacology subject as a basis of therapeutics; and d. correlate and apply the knowledge therapeutically. Text books (Theory) (Author, Title, Edition, Publication Place, Publisher, Year of Publication) a. Tripathi, K. D. Essentials of medical pharmacology. 4 th Ed, 1999. Publisher: Jaypee, Delhi. b. Satoskar, R.S. and Bhadarkar, S.D. Pharmacology and pharmacotherapeutics. 16th edition (single volume), 1999. Publisher: Popular, Dubai. c. Rang, H.P. & Dale, M.M. Pharmacology. 4th edition, 1999. Publisher: Churchill Living stone. Reference books (Theory)(Author, Title, Edition, Publication Place, Publisher, Publication Year) a. Goodman Gilman, A., Rall, T.W., Nies, A.I.S. and Taylor, P. Goodman and Gilman’s The pharmacological Basis of therapeutics. 9th Ed, 1996. Publisher Mc Graw Hill, Pergamon press. b. Craig, C.R.&Stitzel, R.E. Modern Pharmacology. Latest edition. Publisher: Little Brown.Co c. Katzung, B.G. Basic and clinical pharmacology. Latest edition. Publisher: Prentice Hall, Int. d. Shargel and Leon. Applied Biopharmaceutics and pharmacokinetics. Latest edition. Publisher: Prentice Hall, London. Text books (Practical) : Kulkarni, S. K. and Dandia, P. C. Hand book of experimental pharmacology. Latest edition, Publisher: Vallab, Delhi. Reference books (Practical) a. Macleod, L.J. Pharmacological experiments on intact preparations. Latest edition, Publisher: Churchill livingstone.
L. Publisher: Black well Scientific. Latest edition. Fundamentals of experimental pharmacology. . M. Ghosh. Therapeutic uses. c. Latest edition. Textbook of in vitro practical pharmacology.J. contraindications. Macleod. distribution. pharmacokinetics. General Pharmacology a) Introduction. Ian Kitchen. Pharmacology of drugs acting on ANS a) Adrenergic and antiadrenergic drugs b) Cholinergic and anticholinergic drugs c) Neuromuscular blockers d) Mydriactics and miotics e) Drugs used in myasthenia gravis f) Drugs used in Parkinsonism Pharmacology of drugs acting on cardiovascular system a) Antihypertensives b) Anti-anginal drugs c) Anti-arrhythmic drugs d) Drugs used for therapy of Congestive Heart Failure e) Drugs used for hyperlipidaemias 3. interactions and dose and route of administration. Pharmacological experiments on isolated preparations. 3. sub. d. adverse effects. mechanism of action. Publisher: Churchill livingstone. Detailed syllabus and lecture wise schedule : Title of the topic 1.Acute. Latest edition. 2. g) Pre-clinical evaluations h) Drug interactions Note: The term Pharmacology used here refers to the classification. definitions and scope of pharmacology b) Routes of administration of drugs c) Pharmacokinetics (absorption. metabolism and excretion) d) Pharmacodynamics e) Factors modifying drug effects f) Drug toxicity . Publisher: Scientific book agency. pharmacodynamics. Kolkata.acute and chronic toxicity.42 b.N.
Pharmacology of drugs acting on Central Nervous System a) General anesthetics b) Sedatives and hypnotics c) Anticonvulsants d) Analgesic and anti-inflammatory agents e) Psychotropic drugs f) Alcohol and methyl alcohol g) CNS stimulants and cognition enhancers h) Pharmacology of local anaesthetics Pharmacology of Drugs acting on Respiratory tract a) Bronchodilators b) Mucolytics c) Expectorants d) Antitussives e) NasalDecongestants Pharmacology of Hormones and Hormone antagonists a) Thyroid and Antithyroid drugs b) Insulin. . 7. Insulin analogues and oral hypoglycemic agents c) Sex hormones and oral contraceptives d) Oxytocin and other stimulants and relaxants Pharmacology of autocoids and their antagonists a) Histamines and Antihistaminics b) 5-Hydroxytryptamine and its antagonists c) Lipid derived autocoids and platelet activating factor 5.43 4. 6.
Synopsis 10 2. process and conclusion) 3. do patient counselling & provide health screening services to public in community pharmacy. The Pharmaceutical press. know the business and professional practice management skills in community pharmacies. 3.P/ CBG / Lung function) 15 4. c. c. Lippincott Williams & Wilkins. Handbook of pharmacy – health care. Scope: In the changing scenario of pharmacy practice in India. respond to minor ailments and provide appropriate medication. students will be learning various skills such as dispensing of drugs. Comprehensive Pharmacy Review – Edt. Leon Shargel. patient counselling. know pharmaceutical care services. Health Education and Community Pharmacy by N. Reference books: a.S. Community Pharmacists are expected to offer various pharmaceutical care services. Viva – Voce 10 . b. Either the college is having model community pharmacy (meeting the schedule N requirement) or sign MoU with at least 4-5 community pharmacies nearby to the college for training the students on dispensing and counselling activities. WHO consultative group report. appreciate the concept of Rational drug therapy. Major Experiment 30 (Counselling of patients with specific diseases – emphasis should be given on Counselling introduction. and f. Special requirements: 1.P apparatus. responding to minor ailments by providing suitable safe medication. Special equipments like B.5 COMMUNITY PHARMACY (THEORY) Theory : 2 Hrs. e. 2. b. show empathy and sympathy to patients. Minor Experiment(Ability to measure B.44 2. health screening services for improved patient care in the community set up. and apparatus for cholesterol estimation. b. Peak flow meter. Scheme of evaluation (80 Marks) 1. Text Books: a. the student shall be able to – a. content.Edt.Parmar. Glucometer. Robin J Harman. 2. d. In order to meet this demand. /Week 1. Objectives: Upon completion of the course. Prescription Analysis (Analyzing the prescriptions for probable drug interaction and ability to tell the management) 15 5. Drug store & Business management by Mohammed Ali & Jyoti.
coding. and design b) Staff. and treatment & prevention of deficiency disorders Family planning – role of pharmacist Responding to symptoms of minor ailments Relevant pathophysiology. diarrhea. outcomes. various methods of Inventory Control ABC. Pyrexia. Lead time. Syphilis. Hepatitis.content. barriers. and geriatric patients. Essential Drugs concept and Rational Drug Therapy Role of community pharmacist Code of ethics for community pharmacists 3 4 5 6 7 8 9 10 11 12 13 .Definition. OTC medication list & Counselling Health Education WHO Definition of health. Opthalmic symptoms. Commonly occurring Communicable Diseases. Pain. importance. VED. common drug therapy to. pregnant & breast feeding women. Amoebiasis. constipation). Typhoid.45 4. EOQ. Vomiting. causative agents. Lecture wise programme : Topics 1 2 Definition. Dyspepsia. advisory labels Patient medication adherence Definition. Malaria. Strategies to overcome barriers Patient information leaflets. Inventory control in community pharmacy Definition. of community pharmacy Roles and responsibilities of Community pharmacist Community Pharmacy Management a) Selection of site. safety stock Pharmaceutical care Definition and Principles of Pharmaceutical care. and health promotion. GI disturbances (Nausea. Space layout. various stages. role of pharmacist in improving the adherence. Gonorrhea and AIDS Balance diet. legality & identification of medication related problems like drug interactions. design. Factors affecting medication adherence. Health screening services Definition. & layouts. Patient counselling Definition. methods for screening Blood pressure/ blood sugar/ lung function and Cholesterol testing OTC Medication. Clinical presentations and prevention of communicable diseases – Tuberculosis. worms infestations. scope. care for children. stocking c) Legal requirements d) Maintenance of various registers e) Use of Computers: Business and health care soft wares Prescriptions – parts of prescription. Materials. Leprosy.
. Pharmacotherapy: A Pathophysiologic approach . W.Eric T. 1997. 2.46 2. Adis International Limited. Dipiro et al. the controversies in drug therapy. 4th Edn. b. Chapman and Hall publication. Clinical Pharmacy and Therapeutics . Pathology and therapeutics for Pharmacists: A Basis for Clinical Pharmacy Practice Green and Harris. the pathophysiology of selected disease states and the rationale for drug therapy. summarise the therapeutic approach to management of these diseases including reference to the latest available evidence. the therapeutic approach to management of these diseases. h. This will enable the student to understand the pathophysiology of common diseases and their management. e. c.Robins SL. Herfindal. needs to identify the patient-specific parameters relevant in initiating drug therapy. Chapters dealt cover briefly pathophysiology and mostly therapeutics of various diseases. f. and j. describe the pathophysiology of selected disease states and explain the rationale for drug therapy. Relevant review articles from recent medical and pharmaceutical literature.Roger and Walker. f. d. b. Scope of the Subject: This course is designed to impart knowledge and skills necessary for contribution to quality use of medicines. Williams and Wilkins Publication. time-course of clinical and laboratory indices of therapeutic response and adverse effects). Appleton & Lange. b. d. /Week 1. Churchill Livingstone publication. the importance of preparation of individualised therapeutic plans based on diagnosis. c.I (THEORY) Theory : 3 Hrs.6 PHARMACOTHERAPEUTICS . Objectives: At completion of this subject it is expected that students will be able to understand – a. i. time-course of clinical and laboratory indices of therapeutic response and adverse effects). and monitoring therapy (including alternatives. Reference Books a. g. Clinical Pharmacy and Therapeutics .Joseph T. and monitoring therapy (including alternatives. discuss the preparation of individualised therapeutic plans based on diagnosis. Applied Therapeutics:The clinical Use of Drugs. discuss the controversies in drug therapy.B. Lloyd Young and Koda-Kimble MA e. identify the patient-specific parameters relevant in initiating drug therapy.Saunders publication. Text Books a. Avery’s Drug Treatment. Pathologic basis of disease .
viral & bacterial Introduction to rational drug use Definition. case presentation upon discharge.47 3. . Oral contraceptives. follow up the progress and changes made in drug therapy in allotted patients. Electrophysiology of heart and Arrhythmias 2 Respiratory system : Introduction to Pulmonary function test. Hyperlipidaemias . attending ward rounds. Asthma. Angina Pectoris. Role of pharmacist Essential drug concept Rational drug formulations 3 4 5 2./Week Practicals : Hospital postings in various departments designed to complement the lectures by providing practical clinical discussion.6 PHARMACOTHERAPEUTICS . Congestive cardiac failure. Assignments : Students are required to submit written assignments on the topics given to them. Myocardial infarction. Drug induced pulmonary diseases Endocrine system : Diabetes. Pregnancy and breast feeding Ophthalmology: Glaucoma. Conjunctivitis. Osteoporosis General prescribing guidelines for a. Hormone replacement therapy.I (PRACTICAL) Practical : 3 Hrs. Geriatric patients c. A minimum of 20 cases should be presented and recorded covering most common diseases. Thyroid diseases. Topics allotted should cover recent developments in drug therapy of various diseases. Students are required to maintain a record of cases presented and the same should be submitted at the end of the course for evaluation. . Chronic obstructive airways disease. Paediatric patients b. A minimum of THREE assignments [1500 – 2000 words] should be submitted for evaluation. Detailed syllabus and lecture wise schedule : Etiopathogenesis and pharmacotherapy of diseases associated with following systems/ diseases Title of the topic 1 Cardiovascular system: Hypertension.
48 Format of the assignment: 1. 3. 4. promptness. Name and signature of the student. 6. 5. Time allocated for presentation may be 8+2 Min. viva-voce and record maintenance). Minimum & Maximum number of pages. Scheme of Practical Examination: Sessionals Synopsis 05 Major Experiment 10 Minor Experiment 03 Viva 02 Max Marks 20 Duration 03hrs Annual 15 25 15 15 70 04hrs Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity. . 2. Reference(s) shall be included at the end. It shall be computer draft copy. Assignment can be a combined presentation at the end of the academic year.
and Stitzel. d. Goodman and Gilman’s The pharmacological Basis of therapeutics. Reference books (Theory) a. GIT. Pharmacology. b. D. K.P. b. appreciate the importance of pharmacology subject as a basis of therapeutics.V.K. adverse effects. 16 th edition (single volume). precautions. . Delhi.1 PHARMACOLOGY – II (THEORY) Theory : 3 Hrs. II and III. Publisher: Jaypee. contraindications and interaction with other drugs. Publisher: Churchill Living stone. Tripathi. respiratory system. understand the pharmacological aspects of drugs falling under the above mentioned chapters.G. International. Modern Pharmacology. R. Rang.I.. C.E. drugs acting on autacoids. Gupta. c. Latest edition. Text books (Practical) Kulkarni. Hand book of experimental pharmacology. T. M. Publisher: B. and d. Pergamon press. Latest edition. Volume I. R. Latest edition. Publisher: Mc Graw Hill. pharmacology of chemotherapeutic agents. and pharmacology of autocoids and hormones will be concentrated. carry out the animal experiments confidently. B. correlate and apply the knowledge therapeutically. C. 2. c. b. A. pharmacodynamic and pharmacokinetic aspects. and Salunkhe. 9th edition. Nies. uses.M. Text books (Theory) a. dose. New Delhi. Basic and clinical pharmacology. 1999. Publisher: Little Brown and company. Modern Toxicology. c. immune system and hormones. K. 1999. In addition to theoretical knowledge. and Dale.49 Third Year 3. /Week 1. Dubai. D. Scope of the Subject: This subject will provide an opportunity for the student to learn about the drug with regard to classification. 4th edition. route of administration. Objectives of the Subject Upon completion of the subject student shall be able to: a. Craig. 1999. Goodman Gilman.W. essential minerals and principles of toxicology are also taught. P. Metropolitan Book Co. In addition. the basic practical knowledge relevant to therapeutics will be imparted.S. 4 th edition. A. Pharmacology and pharmacotherapeutics. Essentials of medical pharmacology. Gupta. P. Publisher: Prentice Hall. Satoskar. H. Publisher: Popular. Delhi. vitamines.K. S. (p) Ltd. S.R. In this subject. P. and Bhadarkar. 1996. Publisher: Vallab. and Taylor. Latest edition.. and Dandia. Katzung.D. Rall.S.
d. Latest edition. Giardiasis) l) Pharmacology of Anthelmintic drugs m) Chemotherapy of cancer (Neoplasms) Immunopharmacology Pharmacology of immunosuppressants and stimulants Principles of Animal toxicology Acute.J. Latest edition. Pharmacological experiments on intact preparations. Pharmacological experiments on isolated preparations. Ghosh. Publisher: Churchill livingstone. Detailed syllabus and lecture wise schedule: Title of the topic 1. 3. L.J. Latest edition. 4 5. Aminoglycosides. c. Macleod. 3. . Polyene & Polypeptide antibiotics f) Quinolines and Fluroquinolines g) Antifungal antibiotics h) Antiviral agents i) Chemotherapy of tuberculosis and leprosy j) Chemotherapy of Malaria k) Chemotherapy of protozoal infections (amoebiasis. M. b. Fundamentals of experimental pharmacology. Latest edition.N. L. Pharmacology of Drugs acting on Blood and blood forming agents a) Anticoagulants b) Thrombolytics and antiplatelet agents c) Haemopoietics and plasma expanders Pharmacology of drugs acting on Renal System a) Diuretics b) Antidiuretics Chemotherapy a) Introduction b) Sulfonamides and co-trimoxazole c) Penicillins and Cephalosporins d) Tetracyclins and Chloramphenicol e) Macrolides. Kolkata. Publisher: Black well Scientific.50 Reference books (Practical) : a. Textbook of in vitro practical pharmacology. Publisher: Scientific book agency. sub acute and chronic toxicity 2. Ian Kitchen. Macleod. Publisher: Churchill livingstone.
d) The cell cycle: Restriction point.. The gene sequencing.. initiation in eukaryotes. JD. B. trinucleotide repeats and other genetic abnormalities. c) Transcription and Transcription factors: Basic principles of transcription in pro and eukaryotes. Roberts. D. et al. JNK. J. (1998) . LOH... biosensors. b) Gene expression: Expression systems (pro and eukaryotic). Lewis. H. subcellular organelles. (1996) 7 Biopharmaceutical: Biochemistry and Biotechnology by Walsh. translation control and post-translation events Altered gene functions: Mutations. 5 th edition. JD. cell cycle regulators and modifiers. bacterial and eukaryotic DNA replication.. Transcription factors that regulate transcription in pro and eukaryotes.. 2 Molecular Cell Biology By Lodish. Baltimore. P38 kinase. 4 Genes VIII by Lewin. Oncogenes and tumor suppressor genes. acetylation. 3rd edition. ion-channels. (2004) 5 Pharmaceutical Biotechnology.. genetic elements that control gene expression (nucleosomes.. G.. Recombinant DNA technology: principles.. The dynamic cell: The structures and functions of the components of the cell a) Cell and macromolecules: Cellular classification. genome complexity. chromatin structure. Berk. DJA and Sindelar RD (1997) 6 Recombinant DNA by Watson. large macromolecular assemblies b) Chromosome structure: Pro and eukaryotic chromosome structures. tRNA and mRNA processing. Protein synthesis: Mechanisms of protein synthesis. K and Watson. PC.... c) DNA replication: General. Bates. amplifications. M. RNA processing: rRNA. Processes (gene transfer technology) and applications Books: 1 Molecular Biology of the Cell by Alberts B. Ras and PI3-kinase pathways. Gilman. D. Introduction to gene therapy and targeting.51 6. signal transduction pathways (MAP kinase. DNA binding protein families. e) Cell signaling: Communication between cells and their environment. HDACS. by Crommelin. McLennan. mapping and cloning of human disease genes. macromolecules. the flow of genetic information. Bray. deletions.. Raff M. traslocations. A et al. The Gene: Genome structure and function: a) Gene structure: Organization and elucidation of genetic code. 3 Molecular Biology by Turner. histones. AG. AD and White MRH 2 nd edition.
5. 12. 7. 11. Study of theory. e. principle. 6. To carry out bioassay of Histamine using isolated guinea-pig ileum preparation by interpolation method. c) Anticonvulsant activity of drugs using maximal electroshock and pentylene tetrazole methods. To record the dose response curve of Ach using isolated ileum/rectus abdominis muscle preparation. To carry out bioassay of Ach using isolated ileum/rectus abdominis muscle preparation by three point method. Study of physiological salt solutions used in experimental pharmacology. To record the dose response curve of Histamine using isolated guinea-pig ileum preparation. d) Antidepressant activity of drugs using pole climbing apparatus and pentobarbitone induced sleeping time methods. Frogs. 3. d. Mice. 8. Study of agonistic and antagonistic effects of drugs using isolated guinea-pig ileum preparation.52 3. Study of laboratory animals and their handling (a. Mice. Study of laboratory appliances used in experimental pharmacology. b) Antiinflammatory effect of drugs using rat-paw edema method. Rabbits). 13. Scheme of Practical Examination: Sessionals Annual Identification 02 10 Synopsis 04 10 Major Experiment (Bioassay) 08 30 Minor Experiment (Interpretation of 04 10 given Graph or simulated experiment) Viva 02 10 Max Marks 20 70 Duration 3hrs 4hrs Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity. 4. 9. 2. e) Locomotor activity evaluation of drugs using actophotometer and rotorod. promptness. 10. c. procedure involved and interpretation of given results for the following experiments: a) Analgesic property of drug using analgesiometer. To carry out bioassay of Histamine using guinea-pig ileum preparation by three point method. b. f) Cardiotonic activity of drugs using isolated frog heart and mammalian heart preparations.1 PHARMACOLOGY – II (PRACTICAL) Practical : 3 Hrs. Rats. To carry out bioassay of Ach using isolated ileum/rectus abdominis muscle preparation by interpolation method. viva-voce and record maintenance)./Week List of Experiments: 1. Rabbits). Guinea pigs. Study of use of anesthetics in laboratory animals. To study the routes of administration of drugs in animals (Rats. .
quality of equipment.2 PHARMACEUTICAL ANALYSIS (THEORY) Theory : 3 Hrs. Ion-exchange chromatography: Introduction. Gel filtration and affinity chromatography: Introduction. equipment for paper and gel electrophoresis. classification. theory. types of columns. Typical gas chromatogram. Chromatography: Introduction. Electrophoresis: Principles of separation. thermal conductivity detector. types of paper chromatography.international conference for harmonization-guidelines. instrumentation. b. principle. Total quality management. frontal analysis and elution analysis. and applications. factors affecting ion exchange. choice of methods. techniques. a. g.53 3. applications. 2. sources of quality variation. Column Chromatography: Adsorption column chromatography. f. methodology and applications. Quality Assurance: a. principle. GLP. and application. d. technique. c. principles. separation techniques. applications. PC: Introduction. . history. applications and partition chromatography. R f value and applications. stationary phases in GLC & GSC. i. theory. programmed temperature gas chromatography. quality review and documentation. Regulatory control. applications. The following techniques be discussed with relevant examples of pharmaceutical products involving principles and techniques of separation of drugs from excipients. instrumentation. Operational technique. instrumentation-carrier gases. HPTLC: Introduction. Factors affecting column efficiency. and applications. f. DetectorsFlame ionization detectors. TLC: Introduction. b. validation of equipment and validation of analytical instruments and calibration. electron capture detector. control of quality variation. g. types of ion exchange synthetic resins. development techniques. Introduction. h. Concept of statistical quality control. theory. Gas Chromatography: Introduction. c. preparation techniques. e. physical properties. HPLC: Introduction. e. ICH. ISO 9000. Validation methods. derivatisation techniques. d. /Week 1.
Fundamental laws of photometry.Infrared Spectroscopy: Vibrational transitions. Electrometric Methods: Theoretical aspects. sample handling in IR spectroscopy and detectors– Thermocouple.-Visible spectrophotometer – sources of U. advantages and disadvantages of Amperometry over potentiometry. Applications of IR in pharmacy. methods of detecting end point. Pharma applications. Phototube. indicator electrodes. Thermistor. Collimating systems. electrochemical cell. measurement of equilibrium constant and rate constant by spectroscopy. DME. Polarographic maxima and suppressors and applications. types of electrodes used. a. hyperchromic and hypochromic effect. titration procedure. batho-chromic shift. Beer-Lambert’s Law. effect of solvent on absorption spectra. reference and indicator electrode.V. limitation of Beer law. Diode array. reference electrodes. residual current.Theory of electronic. Potentiometric titrations. monochromators.-Visible radiations. .V. Conductometry: Introduction. Bolometer. collimating systems. instrumentation. Potentiometry: Electrical potential. sample cells. Spectra of isolated chromophores. conductometric titrations and applications. Infrared absorption bands. Instrumentation – Photometer. Amperometric Titrations: Introduction.54 3. . Absorption Spectroscopy: . samples cells and following detectors-Photocell. 4. conductivity cell. construction and working of electrodes.-Visible spectroscopy in pharmacy and spectrophotometric titrations. Effect of oxygen on polarographic wave. diffusion current and limiting current. Golay Cells. instrumentation. c. Barrier layer cell. Spectroscopy: Theoretical aspects. frequency – structure correlations. elements of interpretation of data/spectra and application of analytical techniques be discussed on: a.V. Karl Fischer titration. application and its deviation. Instrumentation–IR spectrometer – sources of IR. atomic and molecular spectra. instrumentation. application of the law to single and multiple component analysis. polarographic wave. Polarography: Instrumentation. monochromators. interpretation of data/spectra and analytical applications be discussed on the following topics. measurement of potential and pH. U. auxochromes. d. b. Ilkovic’s equation. hypsochromic shift. molecular structure and infrared spectra. Pyroelectric detector. applications of U.
atomic emission spectrometers. . 10. applications. luminescence. fluorescent indicators. 8. and DSC and DTA. Separation and identification of Sulpha drugs by TLC technique. photographic and photoelectric detection. interferences. electrodes. Applications. reciprocal lattice concept. 2. Instrumentation. Polarimetry: (Introduction only) – Introduction to optical rotatory dispersion. Atomic Absorption Spectrometry: Introduction. polarimeter. 7. X-RAY Diffraction: (Introduction only) – Theory. flame spectrometric techniques and instrumentation and pharmaceutical applications. Study of quenching effect in fluorimetry. Atomic Emission Spectroscopy: Spectroscopic sources. Theory. Thermal Analysis: Introduction. nebulisation. flame and flame temperature. 3.55 . 6. Estimation of drugs by Fluorimetric technique. factors affecting fluorescence./Week List of Experiments: 1. Separation and identification of Amino Acids by Paper Chromatography. Mass Spectroscopy: (Introduction only) – Fragmentation. study of pharmaceutically important compounds estimated by fluorimetry. e. 3. types of c. circular dichroism. diffraction patterns and applications. i. NMR & ESR (introduction only): Introduction.Fluorimetric Analysis: Theory. Conductometric titration of mixture of acids with a strong base. instrumentation and applications. Potentiometric titration of a acid with a strong base. types of ions produced mass spectrum and applications. theoretical aspects and applications. d. Comparison of the UV spectrum of a compound with that of its derivatives. Flame Photometry: Theory. Colourimetric estimation of Supha drugs using BMR reagent. Determination of dissociation constant of indicators using UV-Visible spectroscopy. h. Effect of pH and solvent on the UV spectrum of given compound. 9. 4. 5. f. instrumentation. g. quenching.2 PHARMACEUTICAL ANALYSIS (PRACTICAL) Practical : 3 Hrs. b.
ELBS with Macmillan Press. Chemistry by Chatten. Sounders Manipal College Publishing. 12. East West Press Ltd. I. by A. 6. Spectroscopy by Silverstein.I.P. Text Book of Chemical Analysis. Undergraduate Instrumental Analysis by James.Connors. Textbook of Pharm. CBS Publishers.. by Garrot. E.Mack Publishing Co. . Quantitative Pharma. 11. Canada & Singapore. How to practise GMP-A Plan for total quality control by P. Hampshire.Dept. 17. New York. Agra. Sethi. 20. CBS Publishers. of Health. for HMSO. 2. 12. Inc. Sharma. The Extra Pharmacopoeia – The Pharm. 4.-1996.. London.P. ELBS with Macmillan press. Analysis by Jenkins. London. Comparison of the IR spectrum of a compound with that of its derivatives.. Textbook of Pharm. Analysis (Practical) by Beckett & Stenlake. 16. 18. 5. B. EWP. T and Hasen. Interpretation of NMR spectra of any one compound. 13. Text Book of Pharm. E. U. BPC.. Demonstration of HPLC. 22. Delhi. Delhi. Spring Verlay. 3. Assay of Salicylic Acid by colourimetry.. John Wiley & Sons. 13. Hampshire. The Blakiston division. 9. D.. Brisbane. 21.A. Determination of Chlorides and Sulphates in Calcium gluconate by Nepheloturbidimetric Method. New Delhi. New York Inter Science Publishers. Pennsylvania. Determination of Na/K by Flame Photometry. Singapore. 8. 7. Pharm Analysis by Skoog and West. Chapman & Hall Ltd. Analysis by K. Determination of pKa using pH meter. Demonstration of GC-MS. Demonstration of DSC. 15. Press. John & Wiley & Sons. TLC by Stahl. CBS Publications. 14. Mack Publishing Co. Instrumental Analysis by Willard and Merritt. Text Book of Pharm. PA.K. Analysis by Higuchi.Vogel. 17. 19. Delhi/Madras. 10. CBS Publishers. 14. 18.D. USP . Textbook of Drug Analysis by P. Spectroscopy by William Kemp. Demonstration of HPTLC. Quantitative Drug Analysis. 16. Determination of specific rotation. Easton. Simultaneous estimation of two drugs present in given formulation. New York. The Controller of Publications. The Science & Practice of Pharmacy by Remington Vol-I & II. 19. Reference Books: 1.56 11. 20. 15.. Vandana Publications.
** 9 To study the anxiolytic effect of diazepam in mice using mirrored-chamber apparatus. 15 To study the effect of drugs on heavy metal toxicity.* 13 To study the effects of drugs on vas deferense of the male rat. . ** indicate major experiment & * indicate minor experiment Scheme of Practical Examination: Sessionals Annual Synopsis 05 15 Major Experiment 10 25 Minor Experiment 03 15 Viva 02 15 Max Marks 20 70 Duration 03hrs 04hrs Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity.** 10 To demonstrate the effect of various drugs on the blood pressure and respiration of anaesthetized dog. promptness.* 8 To study the antiinflammatory property of indomethacin against carrageenan-induced paw oedema.** 14 To study the effect of drugs on pesticide toxicity using rats as model.* 7 To study the muscle relaxant property of diazepam in mice using rotarod apparatus.57 Practicals Title of the Experiment: 1 Study of agonistic and antagonistic effects of drugs using Guinea-pig ileum preparation.* 5 To study antihistaminic property of drug using histamine induced anaphylactic reaction in guinea pigs. viva-voce and record maintenance). 11 To study the effect of anthelmintics on earthworms. 12 To study the taming effect of chlorpromazine. 6 To study the apomorphine-induced compulsive behaviour (stereotypy) in mice.** 4 To study the anticonvulsant property of drugs (any one model).** 2 To study the effects of drugs on intestinal motility using frog’s esophagus model* 3 To study the effects of drugs using rat uterus preparation.
Fungal infections. appreciate the needs to identify the patient-specific parameters relevant in initiating drug therapy. Urinary tract infections. Viral infections. HIV & Opportunistic infections. Churchill Livingstone publication Reference books (Theory) a. Detailed syllabus and lecture wise schedule : Etiopathogenesis and pharmacotherapy of diseases associated with following systems / diseases – Title of the topic 1.58 3. Applied Therapeutics: The clinical Use of Drugs. Gout. know the controversies in drug therapy. Drug induced renal disorders . and monitoring therapy (including alternatives. This will enable the student to understand the pathophysiology of common diseases and their management. Scope of the Subject: This course is designed to impart knowledge and skills necessary for contribution to quality use of medicines. /Week 1. Osteoarthritis. Protozoal infection. 3 Renal system Acute Renal Failure. know the therapeutic approach to management of these diseases.Malaria. d. Objectives of the Subject Upon completion of the subject student shall be able to – a. Meningitis. Herfindal. Tuberculosis. Dipiro et al.Joseph T. Chapters dealt cover briefly pathophysiology and mostly therapeutics of various diseases. Clinical Pharmacy and Therapeutics . Gonarrhoea and Syphillis 2 Musculoskeletal disorders Rheumatoid arthritis. Endocarditis. Williams and Wilkins Publication c. and e. time-course of clinical and laboratory indices of therapeutic response and adverse effects).3 PHARMACOTHERAPEUTICS – II (THEORY) Theory : 3 Hrs. Lloyd Young and Koda-Kimble MA] 3. Systemic lupus erythematosus. Septicemia. know the pathophysiology of selected disease states and the rationale for drug therapy b. Chronic Renal Failure.Eric T. Gastroenteritis. Appleton & Lange b. c. know the importance of preparation of individualised therapeutic plans based on diagnosis. Infectious disease: Guidelines for the rational use of antibiotics and surgical Prophylaxis. Respiratory tract infections. Text books (Theory) Clinical Pharmacy and Therapeutics . Spondylitis. 2.Roger and Walker. Renal Dialysis. Pharmacotherapy: A Pathophysiologic approach .
/Week Practicals : Hospital postings in various departments designed to complement the lectures by providing practical clinical discussion. 6. promptness. 3. Impetigo 3. Reference(s) shall be included at the end. leukemia. Format of the assignment : 1.59 4 5 Oncology: Basic principles of Cancer therapy. Scheme of Practical Examination : Sessionals Annual Synopsis 05 15 Major Experiment 10 25 Minor Experiment 03 15 Viva 02 15 Max Marks 20 70 Duration 03hrs 04hrs Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity. Management of chemotherapy nausea and emesis Dermatology: Psoriasis. Students are required to maintain a record of cases presented and the same should be submitted at the end of the course for evaluation. case presentation upon discharge.3 PHARMACOTHERAPEUTICS – II (PRACTICAL) Practical : 3 Hrs. Name and signature of the student. attending ward rounds. . It shall be computer draft copy. Time allocated for presentation may be 8+2 Min. The student shall be trained to understand the principle and practice involved in selection of drug therapy including clinical discussion. A minimum of THREE assignments [1500 – 2000 words] should be submitted for evaluation. A minimum of 20 cases should be presented and recorded covering most common diseases. follow up the progress and changes made in drug therapy in allotted patients. 5. 4. 2. Assignments : Students are required to submit written assignments on the topics given to them. Topics allotted should cover recent developments in drug therapy of various diseases. Scabies. Minimum & Maximum number of pages. viva-voce and record maintenance). Chemotherapy of breast cancer. General introduction to cancer chemotherapeutic agents. Eczema. Assignment can be a combined presentation at the end of the academic year.
know the various parameters in the Drug and Cosmetic Act and rules. D. do. understand the labeling requirements and packaging guidelines for drugs and cosmetics. Scope of the Subject: (4-6 lines): This course exposes the student to several important legislations related to the profession of pharmacy in India. K. S. Qualification and duties –Govt. and appreciate) – a. Reports of the Pharmaceutical enquiry Committee d. H. practice the Professional ethics. W. KK. Deshapande. Objectives of the Subject: Upon completion of the subject student shall be able to (Know. c. labeling and packaging of Drugs And Cosmetics Provisions Relating to Indigenous Systems. Import. N. include the Pharmacy Act. Study of Schedule’s with reference to Schedule B. X. d. medicinal and toilet preparation Act etc.M. Constitution and Functions of DTAB.60 3. 2. 3. C&C1. V. Text books (Theory) Mithal . Various reports of Amendments. Beotra’s the Laws of Drugs. 1988. Singh. Detailed syllabus and lecture wise schedule: Title of the topic 1.The narcotic and psychotropic substances act 1985. Sales. 2. Reference books (Theory) a. E1.A. understand the various concepts of the pharmaceutical legislation in India. Other acts. Eastern Book Company . Objectives. Patent and design act. editor. analyst and Drugs Inspector. Principle and Significance of professional ethics. G. 1998. know the Drug policy. Drugs and Cosmetics Act. Textbook of Forensic Pharmacy. J. professional ethics. 1984.W. 1995. Pharmaceutical Legislations – A brief review. 1940. B M. Critical study of the code of pharmaceutical ethics drafted by PCI. R. Lucknow: Eastern. Mumbai. Calcutta :National. 1987. f. patent and design Act will be discussed. . Allahabad: Law Book House.CDL.. b. e. /Week 1. Delhi: Vallabh prakashan . which are covered. dangerous drugs. Pharmacy Act and Excise duties Act. DPCO. P. F2. Besides this the new drug policy.and its rules 1945. F&F1. be able to understand the concepts of Dangerous Drugs Act.D. The Drugs and Cosmetics Act. A Textbook of forensic pharmacy. Legal definition. c. DPCO 1995 e. FF. 3. F3. along with its amendments are the core of this course. M. Medicines & cosmetics. NK. f. b. Y. Jain. Mumbai: Susmit Publications. The drugs and magic remedies act 1954 and rules 1955. other laws as prescribed by the Pharmacy Council of India from time to time including International Laws. and g. DPCO. g. I.DCC.4 PHARMACEUTICAL JURISPRUDENCE (THEORY) Theory : 2 Hrs.
Constitution and Functions of narcotic & Psychotropic Consultative Committee. 12. National Fund for Controlling the Drug Abuse. Medical and surgical accessories. Patents & design Act-1970. Medicinal and Toilet preparation Act. Dangerous Drugs Act. General Study. Professional Ethics. 2. 3. 5. Objectives Legal Definitions. Name and signature of the student 5. Brief study of prescription and Non-prescription Products. Legal Definitions. Bonded and Non Bonded Laboratory. Homeopathic. 10. Medicinal and Toilet Preparation Act –1955. Drugs (Price control) Order. Diagnostic aids and appliances available in the market. 4. 4. Objectives. Drugs and Cosmetics Act and rules along with its amendments. Study of Salient Features of Drugs and magic remedies Act and its rules. Schedules to the Act. Prevention Of Cruelty to animals Act-1960. Prohibition. Minimum & Maximum number of pages 2. Study of essential Commodities Act Relevant to drugs price control Order. Assignment can be a combined presentation at the end of the academic year. 7. Patent & Proprietory Preparations. Assignments: Format of the assignment 1. Constitution and Functions of State & Central Council. 9. 4. 6. General Study. Legal Definitions. Narcotic Drugs and Psychotropic substances Act-1985 and Rules.61 4. It shall be a computer draft copy 3. . Ware Housing. Patent and Design Act. Various prescription and non-prescription products. Manufacture of Ayurvedic. Drug Price control Order & National Drug Policy (Current). Reference(s) shall be included at the end. Pharmacy Act –1948. Licensing. Control and regulations. 11. ER. 6. Objectives. Time allocated for presentation may be 8+2 Min Case studies relating to 1. New Drug Policy. Registration & Procedure. 8.
Antineoplastic agents 7. Antimalarials 5. Anti-infective agents a) Local anti-infective agents b) Preservatives c) Antifungal agents d) Urinary tract anti-infectives e) Antitubercular agents f) Antiviral agents and Anti AIDS agents g) Antiprotozoal agents h) Anthelmentics i) Antiscabies and Antipedicular agents 3. A study of the development of the following classes of drugs including SAR.62 3. Sulphonamides and sulphones 4. Diureties 11. Modern concept of rational drug design: A brief introduction to Quantitative Structure Activity Relationaship (QSAR). Steroidal Hormones and Adrenocorticoids . Diagnostic agents 12. Hypoglycemic agents 9. mechanism of action. chemical nomenclature. synthesis of important compounds. combinatorial chemistry and computer aided drug design (CADD) and concept of antisense molecules. Cardiovascular agents a) Antihypertensive agents b) Antianginal agents and vasodilators c) Antiarrhythmic agents d) Antihyperlipidemic agents e) Coagulants and Anticoagulants f) Endocrine 8. prodrug. /Week 1. Antibiotics 6.5 MEDICINAL CHEMISTRY (THEORY) Theory : 3 Hrs. 2. brand names of important marketed products and their side effects. Thyroid and Antithyroid agents 10.
I. Waverly Pvt. New Delhi-19. dissociation constants and molar refractivity of compounds for QSAR analysis. h. Preparation of medicinally important compounds or intermediates required for synthesis of drugs.G. Assays of important drugs from the course content. A Text Book of Medicinal Chemistry Vol. g. Wiley-interscience Publication. Organic Drug Synthesis-Ledniser Mitzsher Vol. d. A. I and II by H. Remington. Principles of Medicinal Chemistry.Chemistry M. Pandeya. 6. Roth and A.5 MEDICINAL CHEMISTRY (PRACTICAL) Practical : 3 Hrs. Wilson and Gisvold’s Text book of Organic.O. Kleemann. Medicinal Chemistry. b. Indian Pharmacopoeia 1985 and 1996./Week 1. B. Morgan Publications (I) Pvt. Monograph analysis of important drugs. Pennsylvania. Medicinal and Pharmaceutical Chemistry. 4. Toranto. Ltd.E. 2.E. c.Welly Med. Pharmaceutical Chemistry drug Synthesis Vol. Current Index of Medical Specialities (CIMS) and MIMS India. Varanasi -10. Ltd. Determination of partition coefficients. The Controller of Publications. Publisher. New Delhi. J. Dildayal Nagar.63 3. Civil Lines. I and II.54. Delhi . . The Science and Practice of Pharmacy Vol.Foye. New York. Burgers. MIMS. Walffed Johnwilley and Sons. William. 1 and 2. Lippincott-Raven Publishers-New York. e.E. Philadelphia. I and II by Surendra N.. M. MACK Publishing Company. i. Reference Books: a.. 3. Easton. f. S.
c. rectal. 2. Production and filling of hard gelatin capsules. Liquid orals: Formulation and evaluation of suspensions. Pharmaceutical dosage forms. 4. quality control tests for soft gelatin capsules. understand the principle involved in formulation of various pharmaceutical dosage forms. /Week 1. trans dermal. Rowlings Text book of Pharmaceutics c.64 3. prepare various pharmaceutical formulation.II and III by lachman b. parentral. Type of coating. perform evaluation of pharmaceutical dosage forms. Remington’s Pharmaceutical Sciences b. quality control tests for capsules. nasal. Stability of these preparations 5. Tutorial Pharmacy – Cooper &Gun Reference books (Theory) a. Capsules. their role in clinical situations. do. Text books (Theory) a. viz. Vol. Ophthalmic preparations (Semi – Solids): Introduction and classification Factors affecting absorption and anatomy of skin Packaging storage and labeling. understand and appreciate the concept of bioavailability and bioequivalence. ocular . Jellies Types of jellies Formulation of jellies Suppositories. Tablets: Formulation of different types of tablets.6 PHARMACEUTICAL FORMULATIONS (THEORY) Theory : 2 Hrs. Raw material for shell. Tablet coating. Method of preparation. USP/BP/IP 3. Parenterals Introduction Containers used for Parenterals (including official tests) Formulation of large and small volume Parenterals Sterilization 6. I. Ointments Types of Ointment Base Preparation of ointment. Pharmaceutical dosage form. and d. b. Types Packaging 7.concept and classification 2. Detailed syllabus and lecture wise schedule: Title of the topic 1. implants. quality control tests for coated tablet. appreciate) – a. Objectives of the Subject: Upon completion of the subject student shall be able to (Know. emulsions and solutions. finishing. Scope of the Subject: Scope and objectives of the course: Subject deals with the formulation and evaluation of various pharmaceutical dosage forms. buccal. tablet excipients. Definition and concept of Controlled and novel Drug delivery systems with available examples. granulation techniques quality control and evaluation of tablets. 3. Production and filling of soft gelatin capsules.
promptness./Week List of Experiments : 1. Antacid suspensions. Evaluation of Pharmaceutical formulations (QC tests) a. Tablet coating (demonstration) 2. Manufacture of Tablets a. Tablets prepared by direct compression. Tooth paste and tooth powders. c. Chewable tablet. Soluble tablet. d. 6.Aluminum hydroxide gel Formulation of semisolids and evaluation by assay a. Capsules c.65 3. Dextrose and Sodium chloride injection/ infusion. Salicyclic acid and benzoic acid ointment b.6 PHARMACEUTICAL FORMULATIONS (PRACTICAL) Practical : 3 Hrs. d. Tablets b. Calcium gluconate injection c. Solution: Paracetamol Syrup b. 4. 7. Sodium chloride infusion. . viva-voce and record maintenance). Formulation and filling of hard gelatin capsules Manufacture of parenterals a. 8. Cold cream and vanishing cream c. Clear liquid shampoo d. 5. Ordinary compressed tablet-wet granulation b. Scheme of Practical Examination : Sessionals Annual Synopsis 05 15 Major Experiment 10 25 Minor Experiment 03 15 Viva 02 15 Max Marks 20 70 Duration 03hrs 04hrs Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity. Gel formulation Diclofenac gel Cosmetic preparations a. 3. Ascorbic acid injection b. Injections Formulation of two liquid oral preparations and evaluation by assay a. Lipsticks b.
Eric T. e.1 PHARMACOTHERAPEUTICS – III (THEORY) Theory : 3 Hrs. b. Pathologic basis of disease . to discuss the preparation of individualised therapeutic plans based on diagnosis. 4th Edn. Pharmacotherapy: A Pathophysiologic approach . Relevant review articles from recent medical and pharmaceutical literature. identify the patient-specific parameters relevant in initiating drug therapy. to summarize the therapeutic approach to management of these diseases including reference to the latest available evidence.Joseph T. c. Herfindal. needs to identify the patient-specific parameters relevant in initiating drug therapy. W. Objectives: At completion of this subject it is expected that students will be able to understand – a. Appleton & Lange Reference Books a. Avery’s Drug Treatment. Williams and Wilkins Publication d.66 Fourth Year 4. Text Books a. time-course of clinical and laboratory indices of therapeutic response and adverse effects). 1997. Lloyd Young and Koda-Kimble MA e. This will enable the student to understand the pathophysiology of common diseases and their management. /Week 1. and j.Robins SL. i. the importance of preparation of individualised therapeutic plans based on diagnosis. Churchill Livingstone publication b. Pathology and therapeutics for Pharmacists: A Basis for Clinical Pharmacy Practice Green and Harris. g. Dipiro et al. the pathophysiology of selected disease states and the rationale for drug therapy. h. the therapeutic approach to management of these diseases. describe the pathophysiology of selected disease states and explain the rationale for drug therapy. Clinical Pharmacy and Therapeutics . the controversies in drug therapy. f.Saunders publication b. . Clinical Pharmacy and Therapeutics . to discuss the controversies in drug therapy. Adis International Limited. f. Chapters dealt cover briefly pathophysiology and mostly therapeutics of various diseases. 2.B. and monitoring therapy (including alternatives. d. Applied Therapeutics: The clinical Use of Drugs. Scope : This course is designed to impart knowledge and skills necessary for contribution to quality use of medicines. and monitoring therapy (including alternatives. Chapman and Hall publication c.Roger and Walker. time-course of clinical and laboratory indices of therapeutic response and adverse effects).
2 Haematological system: Anaemias. headaches. 4 Psychiatry disorders: Schizophrenia. promptness. Name and signature of the student 6. A minimum of THREE assignments [1500 – 2000 words] should be submitted for evaluation. 6 Evidence Based Medicine Assignments: Students are required to submit written assignments on the topics given to them. Scheme of Practical Examination : Sessionals Annual Synopsis 05 15 Major Experiment 10 25 Minor Experiment 03 15 Viva 02 15 Max Marks 20 70 Duration 03hrs 04hrs Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity.67 4.1 PHARMACOTHERAPEUTICS – III (PRACTICAL) Practical : 3 Hrs. Venous thromboembolism. Reference(s) shall be included at the end. Minimum & Maximum number of pages 2. 3. viva-voce and record maintenance). Sleep disorders. Each student should present at least two medical cases they have observed and followed in the wards. Gastro Esophageal Reflux Disease. Format of the assignment: 1. Topics allotted should cover recent developments in drug therapy of various diseases. Parkinsonism. Etiopathogenesis and pharmacotherapy of diseases associated with following systems/ diseases: Title of the topic 1 Gastrointestinal system: Peptic ulcer disease./Week Practicals: Hospital postings for a period of at least 50 hours is required to understand the principles and practice involved in ward round participation and clinical discussion on selection of drug therapy. Inflammatory bowel disease. Obsessive Compulsive disorders 5 Pain management including Pain pathways. Liver disorders . Viral hepatitis including jaundice. Affective disorders. neuralgias. Anxiety disorders.Alcoholic liver disease. and Drug induced liver disorders. Alzheimer's disease. . Drug induced blood disorders. Stroke. Assignment can be a combined presentation at the end of the academic year 4. Time allocated for presentation may be 8+2 Min. It shall be computer draft copy 5. 3 Nervous system: Epilepsy. Students are required to maintain a record of 15 cases observed in the ward and the same should be submitted at the end of the course for evaluation.
Newsletter . provide unbiased drug information to the doctors. know various drug distribution methods. b.E. Revised by R. drug dispensing. /Week 1. drug information. 2. A text book of Hospital Pharmacyby S. Handbook of pharmacy – health care. d.S. Edt. appreciate the practice based research methods. Robin J Harman.Merchant & Dr. know the professional practice management skills in hospital pharmacies.K. Text books: (latest editions) a. and therapeutic drug monitoring for improved patient care.Research and ethical committee d) developing therapeutic guidelines e) Hospital pharmacy communication .2. c. The Pharmaceutical press. Hassan b.2 HOSPITAL PHARMACY (THEORY) Theory : 2 Hrs.S. Lecture wise programme : Topics 1 Hospital . c. R. 3. b. Qadry. and f.K. appreciate the stores management and inventory control. for successful practice of Hospital Pharmacy. Infrastructure & work load statistics b) Management of materials and finance c) Roles & responsibilities of hospital pharmacist 3 The Budget – Preparation and implementation 4 Hospital drug policy a) Pharmacy and Therapeutic committee (PTC) b) Hospital formulary c) Hospital committees . Vol.its Organisation and functions 2 Hospital pharmacy-Organisation and management a) Organizational structure-Staff. patient counselling. the student shall be able to – a. WHO consultative group report.H. Hospital pharmacy by William .Infection committee . Objectives: Upon completion of the course. Part –B.P.Goyal & R. Pharmacy Practice section.68 4. Parikh References: a. J. manufacturing of parenteral preparations. e. Scope: In the changing scenario of pharmacy practice in India. the students are required to learn various skills like drug distribution. know the manufacturing practices of various formulations in hospital set up.
Evaluation of prescriptions generated in hospital for drug interactions and find out the suitable management. capsules. and limitations./Week 1. 2. Drug information queries. various methods of Inventory Control ABC. 3. Lead time. EOQ. 6. Different phases of clinical trials with elements to be evaluated.2 HOSPITAL PHARMACY (PRACTICAL) Practical : 3 Hrs. Design and Management of Hospital pharmacy department for a 300 bedded hospital. powders.69 5 Hospital pharmacy services a) Procurement & warehousing of drugs and Pharmaceuticals b) Inventory control Definition. . 3. safety stock c) Drug distribution in the hospital i) Individual prescription method ii) Floor stock method iii) Unit dose drug distribution method d) Distribution of Narcotic and other controlled substances e) Central sterile supply services – Role of pharmacist Manufacture of Pharmaceutical preparations a) Sterile formulations – large and small volume parenterals b) Manufacture of Ointments. granules. Pharmacy and Therapeutics committee – Organization. 2. Assessment of drug interactions in the given prescriptions Manufacture of parenteral formulations. 4. Various sources of drug information and systematic approach to provide unbiased drug information. 7. VED. Liquids. and powders d) Total parenteral nutrition Continuing professional development programs Education and training Radio Pharmaceuticals – Handling and packaging Professional Relations and practices of hospital pharmacist 6 7 8 9 4. and creams c) Manufacturing of Tablets. 5. Preparation of ABC analysis of drugs sold in one month from the pharmacy. functions. Inventory control List of Assignments: 1. Development of a hospital formulary for 300 bedded teaching hospital 4.
Scheme of Practical Examination: Sessionals Annual Synopsis 05 15 Major Experiment 10 25 Minor Experiment 03 15 Viva 02 15 Max Marks 20 70 Duration 03hrs 04hrs Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity. Each college should sign MoU with nearby local hospital having minimum 150 beds for providing necessary training to the students’ on hospital pharmacy activities. 2.70 Special requirements: 1. . Well equipped with various resources of drug information. viva-voce and record maintenance). promptness.
Prentice Hall publication. pharmacist interventions) b. American Society of Health System Pharmacists Inc. Clinical Pharmacokinetics . appreciate) – a. Patient counseling g.The Society of Hospital Pharmacists of Australia. assess and monitor adverse drug reaction. c. 2.Leon Shargel. Ward round participation c. Essential concepts and skills. Drug information and poisons information e. ISSBN8125026 References a.71 4. Sanford Bolton. Biopharmaceutics and Applied Pharmacokinetics . detect. b. Australian drug information -Procedure manual. Dr. Adverse drug reaction management d. and f. Drug utilisation evaluation (DUE) and review (DUR) h. d. retrieve. e. Practice Standards and Definitions . /Week 1. Williams and Wilkins Publication.Ltd. Quality assurance of clinical pharmacy services . The Society of Hospital Pharmacists of Australia. b. d. monitor drug therapy of patient through medication chart review and clinical review.Rowland and Tozer.G. interpret selected laboratory results (as monitoring parameters in therapeutics) of specific disease states. Text books (Theory) a. Drug therapy monitoring (medication chart review. Practical and clinical applications. c. Marcel Dekker. Definitions. c. development and scope of clinical pharmacy 2. clinical review. b. Inc. Introduction to daily activities of a clinical pharmacist a. interpret and formulate drug or medicine information. analyse.Scott LT.Parthasarathi etal. Medication history f. Orient Orient Langram Pvt. A text book of Clinical Pharmacy Practice. Objectives of the Subject : Upon completion of the subject student shall be able to (Know. do. Pharmaceutical statistics.3 CLINICAL PHARMACY (THEORY) Theory : 3 Hrs. Basic skills in interpreting laboratory data . obtain medication history interview and counsel the patients. Detailed syllabus and lecture wise schedule: Title of the topic 1. identify and resolve drug related problems.
Haematological. medication history interview. Case studies related to laboratory investigations (4 Nos) d. Critical evaluation of biomedical literature 10. definition and aims of pharmacovigilance b.Classification. Reporting. including patient counselling techniques. Role of pharmacist in management of ADR. Establishing a Drug Information Centre f.organization & information resources 6. monitoring. Critical evaluation of drug information and literature d. Answering drug information questions (4 Nos) b.72 3. mechanism. Preparation of written and verbal reports e. evaluation. Introduction to drug information resources available b. Patient medication history interview (3 Nos) . 8. Poisons information. Drug & Poison information a. a. and interpretation of test results a.3 CLINICAL PHARMACY (PRACTICAL) Practical : 3 Hrs. Systematic approach in answering DI queries c. Liver function. Medication errors 4. Patient medication counselling (4 Nos) c. Scope. presentation of cases./Week Students are expected to perform 15 practicals in the following areas covering the topics dealt in theory class. Pulmonary Function Tests 5. causality assessment [different scales used] c. Tests associated with cardiac disorders c. thyroid function tests b. Microbiological culture sensitivity tests e. Renal function. its structure and use in evaluation of drug therapy & Understanding common medical abbreviations and terminologies used in clinical practices. preventing & management of ADRs d. 4. Clinical laboratory tests used in the evaluation of disease states. Adverse drug reactions . Patient data analysis The patient's case history. Fluid and electrolyte balance d. Communication skills. 7. Pharmacovigilance a. Pharmaceutical care concepts 9. predisposing factors.
2. Time allocated for presentation may be 8+2 Min. Drug information. Minimum & Maximum number of pages. Patient medication counselling. Reference(s) shall be included at the end.73 Assignment: Students are expected to submit THREE written assignments (1500 – 2000 words) on the topics given to them covering the following areas dealt in theory class. 5. Critical appraisal of recently published articles in the biomedical literature which deals with a drug or therapeutic issue. Assignment can be a combined presentation at the end of the academic year. 6. 3. . Patient medication history interview. Format of the assignment: 1. It shall be computer draft copy. Name and signature of the student. 4.
Epi Info. piecharts. Wilcoxan rank sum test. 2.4 BIOSTATISTICS AND RESEARCH METHODOLOGY (THEORY) Theory : 2 Hrs. Pearsonn’s and Spearmann’s correlation and correlation co-efficient. variation of mean. power of a study d) Report writing and presentation of data 2 Biostatistics 2.1 a) Introduction b) Types of data distribution c) Measures describing the central tendency distributions. . e) Introduction to statistical software: SPSS. determination of sample size to obtain a confidence interval of specified width. standard deviation. Kruskal-Wall is test (one way ANOVA) d) Linear regression and correlation. level of significance. interventional studies.2 Data graphics Construction and labeling of graphs. Detailed syllabus and lecture wise schedule 1 Research Methodology a) Types of clinical study designs: Case studies. Mann Whitney U test. /Week 1. median.Introduction.average. mode d) Measurement of the spread of data-range. b) Level of significance (Parametric data). variance. standard error of mean.3 Basics of testing hypothesis a) Null hypothesis. Analysis of Variance (one-way and two-way) c) Level of significance (Non-parametric data). P value.74 4. histogram. Wilcoxan’s signed rank test. power of test.students t test (paired and unpaired). semilogarthimic plots 2. coefficient of variation. statistical estimation of confidence intervals. chi Square test. scatter plots. observational studies.Sign test. SAS. b) Designing the methodology c) Sample size determination and Power of a study Determination of sample size for simple comparative experiments.
NewYork. Pharmaceutical statistics. attributable risk 3. Computer applications in pharmacy Computer System in Hospital Pharmacy: Patterns of Computer use in Hospital Pharmacy – Patient record database management. patient medication profiles.4 Statistical methods in epidemiology Incidence and prevalence. Medication order entry – Drug labels and list – Intravenous solution and admixture. Drug Information.practical and clinical applications. relative risk. b. McGraw Hill Publications 2006 . Management report & Statistics. Inventory control. Karen L Kier. Computer In Community Pharmacy Computerizing the Prescription Dispensing process Use of Computers for Pharmaceutical Care in community pharmacy Accounting and General ledger system Drug Information Retrieval & Storage : Introduction – Advantages of Computerized Literature Retrieval Use of Computerized Retrieval Reference books: a.75 2. 3rd edition. Sanford Bolton 3rd edition. publisher Marcel Dekker Inc. John E Stanovich .A Guide for Pharmacists. Patrick M Malone.
8. Pharmacokinetics 2. One compartment open model. Nonlinear Pharmacokinetics. Bioavailability study protocol. Methods of Assessment of Bioavailability . MRT for various compartment models. b. Multiple – Dosage Regimens. Introduction to Pharmacokinetics. Pharmacokinetic model d.5 BIOPHARMACEUTICS AND PHARMACOKINETICS (THEORY) Theory : 3 Hrs. Intravenous Injection (Bolus) b. c. Drug levels in blood. Bioavailability and Bioequivalence. Pharmacokinetic study. a. Michaelis-menton method of estimating parameters. Repititive Intravenous injections – One Compartment Open Model b.76 4. c. 3. b. Introduction. a. 4. Biopharmaceutics 1. IV bolus. b. Drug Distribution. /Week 1. Compartment models e. Repititive Extravascular dosing – One Compartment Open model c. 2. a. Statistical Moment Theory. b. Mathematical model b. Introduction to Biopharmaceutics a. Noncompartmental Pharmacokinetics. a. Introduction b. Physiological Pharmacokinetic model. c. a. Intravenous infusion. c. c. Multiple Dose Regimen – Two Compartment Open Model 6. Absorption of drugs from gastrointestinal tract. a. Two compartment open model. Drug Elimination. Factors causing Non-linearity. Multicompartment models. 7. a. IV infusion and oral administration 5.
1987. Vallabh Prakashan Pitampura. Comparison of dissolution studies of two different marketed products of same drug. . Bio pharmaceutics and Pharmacokinetics-A Treatise. Biopharmaceutics and Pharmacokinetics. New York 1996. Improvement of dissolution characteristics of slightly soluble drugs by some methods. Pennsylvnia. Extent of plasma-protein binding studies on the same drug (i. on animals and human volunteers. Bioavailability and Bioequivalence. Pennsylvania 1989. 12. c.. 11.Jaiswal. By Mack Publishing Company. C. By Swarbrick g.M. Marcel Dekker Inc. Hand Book of Clinical Pharmacokinetics.e. AUMC. Publishing Company.5 BIOPHARMACEUTICS AND PHARMACOKINETICS (PRACTICAL) Practical : 3 Hrs. MRT etc. By Abdou H. R. 4. By Milo Gibaldi and Laurie Prescott by ADIS Health Science Press. Trimethoprim. Ke. Effect on contact time on the plasma protein binding of drugs. 5. Bioavailability studies of some commonly used drugs on animal/human model. By Robert F Notari f.77 4. Influence of polymorphism on solubility and dissolution.(eg) Tetracycline. Mercel Dekker Inc. Milo Gibaldi b. Protein binding studies of a highly protein bound drug and poorly protein bound drug. Delhi h. Philadelphia. Cilincal Pharmacokinetics. Determination of renal clearance. 3. Mack. Remington’s Pharmaceutical Sciences. Brahmankar and Sunil B. i. Dissolution. References: a. highly and poorly protein bound drug) at different concentrations in respect of constant time. t1/2. j. Lea and Febrger. AUC. James Swarbrick. Pharmacokinetics: By Milo Glbaldi Donald. 8. 2. e. Biopharmaceutics. By D. k. 1995. Biopharmaceutics and Clinical Pharmacokinetics-An introduction 4th edition Revised and expanded by Rebort F Notari Marcel Dekker Inn. d. 10. Calculation of Ka. Concepts and Applications: By Malcolm Rowland and Thomas. Calculation of elimination half-life for different drugs by using urinary elimination data and blood level data. James. In vitro absorption studies. Aspirin etc. New York and Basel. 7. Calculation of AUC and bioequivalence from the given data for two drugs. 13. Sulphamethoxzole. 14. N. Biopharmaceutics and Clinical Pharmacokinetics by. 15. Encyclopedia of Pharmaceutical Technology. M. Tozen. Bioequivalency studies on the different drugs marketed. Vol 13. 16. from blood profile data. 9. Absorption studies in animal inverted intestine using various drugs. 6. Roylan./Week 1. Studying metabolic pathways for different drugs based on elimination kinetics data. Cmax. Calculation of bioavailability from urinary excretion data for two drugs.
f) Paracetamol and salicylates. early manifestations. Mycotoxins. HANDBOOK OF FORENSIC MEDICINE AND TOXICOLOGY. General principles involved in the management of poisoning Antidotes and the clinical applications. j) Radiation poisoning 8. Thirteenth edition 2003 Paras Publication. V V Pillay. 10. general management as first aid. Gut Decontamination. 3. Plants poisoning. c) Antidepressants d) Barbiturates and benzodiazepines. Food poisonings 12. 2. ELLENHORNS MEDICAL TOXICOLOGY – DIAGNOSIS AND TREATMENT OF POISONING. Hyderabad . mercury. Venomous snake bites: Families of venomous snakes. Toxicokinetics. pyrethroids. b) Opiates overdose. g) Non-steroidal anti-inflammatory drugs. Substance abuse: Signs and symptoms of substance abuse and treatment of dependence a) CNS stimulants :amphetamine b) Opioids c) CNS depressants d) Hallucinogens: LSD e) Cannabis group f) Tobacco References: a. copper 9.6 CLINICAL TOXICOLOGY (THEORY) Theory : 2 Hrs. i) Caustics: inorganic acids and alkali. /Week 1. h) Hydrocarbons: Petroleum products and PEG. complications and snake bite injuries. Elimination Enhancement. Clinical symptoms and management of chronic poisoning with the following agents – Heavy metals: Arsenic. Mushrooms. e) Alcohol: ethanol. Supportive care in clinical Toxicology. clinical effects of venoms. 11. organochlorines. Second edition. Williams and Willkins publication. lead. Matthew J Ellenhorn. iron. methanol. 4. Envenomations – Arthropod bites and stings. 7. 5.78 4. London b. carbamates. Clinical symptoms and management of acute poisoning with the following agents – a) Pesticide poisoning: organophosphorous compounds. 6.
Overview of regulatory environment in USA. Europe and India. Clinical research associate d. Central drug standard control organisation (CDSCO) guidelines 6. GCP. Regulatory authority 11. Informed consent Process 13. Sponsor b. responsibilities. . Composition. Good Clinical Practice – ICH. Drug development process: Introduction Various Approaches to drug discovery 1. 3. Designing of clinical study documents (protocol. Pharmacological 2.79 Fifth year 5. Toxicological 3. Investigators c. Challenges in the implementation of guidelines 7. PIC with assignment) 12.1 CLINICAL RESEARCH (THEORY) Theory : 3 Hrs. Dosage form 2. Safety monitoring in clinical trials. /Week 1. CRF. Abbreviated New Drug Application submission. Drug characterization 5. Clinical development of drug: 1. 5. Introduction to Clinical trials 2. IND Application 4. Ethical guidelines in Clinical Research 8. Role and responsibilities of clinical trial personnel as per ICH GCP a. ICF. Various phases of clinical trial. Methods of post marketing surveillance 4. 10. Auditors e. Contract research coordinators f. Data management and its components 14. procedures of IRB / IEC 9.
80 References : a. 10th Edn. May 1996. b. Guideline for Good Clinical Practice. Indian Council of Medical Research. c. LE Limbard. Good Clinical Practices-Guidelines for Clinical Trials on Pharmaceutical Products in India. Textbook of Clinical Trials edited by David Machin. Principles of Clinical Research edited by Giovanna di Ignazio. New Delhi. Clinical Data Management edited by R K Rondels. . McGraw Hill Publications. Second Edition. Ethical Guidelines for Biomedical Research on Human Subjects 2000. Central Drugs Standard Control Organization. Goodman & Gilman: JG Hardman. C F Webbs. Wiley Publications. d. ICH Harmonised Tripartite Guideline. March 2005. Di Giovanna and Haynes. New Delhi: Ministry of Health.E6. John Wiley and Sons. e. 2001. Jan 2000. 2001. g. Simon Day and Sylvan Green. f. S A Varley. International Conference on Harmonisation of Technical requirements for registration of Pharmaceuticals for human use.
pharmacoepidemiology and risk management. aims and applications.benefit. Applications of Pharmacoeconomics Software and case studies . meta – analysis studies. Monetary units. Sources of data for pharmacoepidemiological studies Ad Hoc data sources and automated data systems. hospital pharmacoepidemiology. Measurement of outcomes in pharmacoepidemiology Outcome measure and drug use measures Prevalence. cost utility 3. cost – effectiveness. drug induced birth defects. defined daily doses and prescribed daily doses. Pharmacoepidemiology : Definition and scope: Origin and evaluation of pharmacoepidemiology need for pharmacoepidemiology. medication adherence measurement Concept of risk in pharmacoepidemiology Measurement of risk. Selected special applications of pharmacoepidemiology Studies of vaccine safety. cost. attributable risk and relative risk. case –cohort studies. needs of pharmacoeconomic evaluations Role in formulary management decisions Pharmacoeconomic evaluation Outcome assessment and types of evaluation Includes theoretical aspects of various methods and practical study of various methods with the help of case studies for individual methods: Cost – minimization. 2. history. /Week 1. units of drugs dispensed. cohort studies. Phrmacoeconomics: Definition. case series. prescription event monitoring and record linkage system.2 PHARMACOEPIDEMIOLOGY AND PHARMACOECONOMICS (THEORY) Theory : 3 Hrs. cross – sectional studies. case control studies. spontaneous reporting.81 5. number of prescriptions. incidence and incidence rate. surveys of drug use. case reports. time-risk relationship and odds ratio Pharmacoepidemiological methods Includes theoretical aspects of various methods and practical study of various methods with the help of case studies for individual methods Drug utilization review.
Population Pharmacokinetics. c. Adaptive method or Dosing with feed back. Indications for TDM. Pharmacokinetics of Drug Interaction: a. d. Pharmacokinetic/Pharmacodynamic Correlation in drug therapy. Pharmacokinetic considerations c.82 5. Measurement of Glomerular Filtration rate and creatinine clearance. Design of dosage regimens: Nomograms and Tabulations in designing dosage regimen. Individualization of drug dosage regimen (Variability – Genetic. Protocol for TDM. General approach for dosage adjustment in Renal disease. and Organ transplantations. f. Dosage adjustment in Renal and hepatic Disease. /Week 1. Extracorporeal removal of drugs. Drug dosing in the elderly and pediatrics and obese patients. 7. a. Interacting drugs). e. g. c. Inhibition of Biliary Excretion. c. Dosage adjustment for uremic patients. Renal impairment b. 4. Pharmacokinetic drug interactions b. 2. a. Seizure disorders. Inhibition and Induction of Drug metabolism c. b. Genetic Polymorphism in Drug Transport and Drug Targets. Therapeutic Drug monitoring: a. Introduction to Bayesian Theory. Age and Weight . e.3 CLINICAL PHARMACOKINETICS AND PHARMACOTHERAPEUTIC DRUG MONITORING (THEORY) Theory : 2 Hrs. Introduction to Clinical pharmacokinetics. b. Conversion from intravenous to oral dosing. Pharmacogenetics a. 3. 6. 5. d. Genetic polymorphism in Drug metabolism: Cytochrome P-450 Isoenzymes. Determination of dose and dosing intervals. Effect of Hepatic disease on pharmacokinetics. Analysis of Population pharmacokinetic Data. Introduction b. Pharmacogenetics and Pharmacokinetics/Pharmacodynamic considerations . TDM of drugs used in the following disease conditions: cardiovascular disease. disease. Psychiatric conditions.
1948.D. Surgery 2. and Pharm.D. Psychiatry 5. Orthopedics (iii)Location of the Hospital Within the same limits of Corporation or Municipality or Campus with Medical Faculty involvement as adjunct faculty. 3. and any three specialization of the following 1. Corporate type hospital with minimum 300 beds with clearly defined Memorandum of Understanding including housing pharmacy practice department with minimum carpet area of 30 square feet per student along with consent to provide the professional manpower to support the programme.83 APPENDIX-B (See regulation 9) CONDITIONS TO BE FULFILLED BY THE ACADEMIC TRAINING INSTITUTION 1) Any authority or institution in India applying to the Pharmacy Council of India for approval of courses of study for Pharm. (ii) Speciality a) Tertiary care hospitals are desirable b) Medicine[compulsory].Pharm course as provided under section 12 of the Pharmacy Act. Teaching hospital recognised by the Medical Council of India or University. (i) Hospital Details 1.D. 2) Pharm. 2. (Post Baccalaureate) under sub-section (1) of section 12 of the Pharmacy Act. b) have 300 bedded hospital attached to it. Skin and VD 6. 4. and Pharm. Institution with their own hospital of minimum 300 beds. Gynecology and obstetrics 4. . or a Government hospital not below the level of district headquarter hospital with 300 beds with clearly defined Memorandum of Understanding including housing pharmacy practice department with minimum carpet area of 30 square feet per student along with consent to provide the professional manpower to support the programme. Number of institutions which can be attached to one hospital shall be restricted by the student pharmacist to bed ratio of 1:10. 1948 shall comply with the infrastructural facilities as prescribed by the Pharmacy Council of India from time to time. Pediatrics 3. (Post Baccalaureate) programmes shall be conducted only in those institutions which a) are approved by the Pharmacy Council of India for B.D.
M.Pharm in Pharmaceutics 19. 7.Pharm in Pharmacy practice Computer Science or MCA Computer Application in pharmacy Mathematics M. 6.Pharm in Pharmacology or Pharmacy practice M. 16.Pharm Pharmacy practice or Pharmacology M. ii) Subject wise specialisation of the Teaching Staff : S. 12.Pharm in Pharmacy practice or Pharmacology or Pharmaceutics Hospital Pharmacy M. 10. 15. 14. 2.84 3) TEACHING STAFF REQUIREMENT i) Staff Pattern : All faculty shall be full time. M. 9.Pharm in Pharmacology or Pharmacy practice M.Pharm in Pharmaceutics 4. Pharmacy Practice Human Anatomy & Physiology Pharmaceutics (Dispensing & General Pharmacy) Pharmacognosy-I Pharmaceutical Organic Chemistry-I Pharmaceutical Inorganic Chemistry Pharmaceutical microbiology Pathophysiology Applied Biochemistry & Clinical Chemistry Pharmacology-I Pharmaceutical Jurisprudence Pharmacology-II Specialisation required M. Subject 1. 11. (Maths) .Pharm in Pharmaceutical chemistry or Pharmaceutical Analysis or Quality assurance or Bulk Drug M.No. M. 17.Sc. 8.Pharm in Pharmaceutics or Pharmaceutical Biotechnology M.Pharm in Pharmacology or Pharmacy practice Pharmaceutical Dosage M.Pharm Pharmacy practice or II and III Pharmacology Community Pharmacy M. However part time perceptors in hospital shall be allowed. 13.Pharm in Pharmacology or Pharmacy practice or Pharmaceutical chemistry M.Pharm in Pharmaceutics or Industrial Forms Pharmacy Pharmacotherapeutics –I. 18.Pharm in Pharmacy practice or Pharmacology or Pharmaceutics Clinical Pharmacy M.Pharm in Pharmaceutical chemistry or Pharmaceutical Analysis or Quality assurance or Bulk Drug M. M. 5.Pharm in Pharmacognosy M. 3.Pharm in Pharmacy Practice or Pharmacology or Pharmaceutics.
1 1 2 1 1 3 1 1 2 1 1 1 1 2 3 Professor Asst. ii) Registration as a pharmacist under the Pharmacy Act. iii) Master’s degree in appropriate branch of specialization in Pharmacy (M. Assistant Professor Three years experience in Teaching or Research at the level of Lecturer or equivalent. 2.Pharm).Pharm). iii) First Class Master’s degree in appropriate branch of specialization in Pharmacy (M. Professor Lecturer No.Pharm) EXPERIENCE No minimum requirement. CADRE Lecturer QUALIFICATIONS i) Basic degree in pharmacy (B. 1. Lecturer and others : Sl.Pharm) i) Basic degree in pharmacy (B. Professor Lecturer Department of Pharmaceutical Chemistry (Including Pharmaceutical Analysis) Department of Pharmacology Professor Asst. No. . Professor Lecturer iv) Prescribed qualifications and experience for Professor. Professor Lecturer Department of Pharmacy Professor Practice Asst. ii) Registration as a pharmacist under the Pharmacy Act.85 iii) Teaching Staff : Department/Division Department of Pharmaceutics Name of the post Professor Asst. Assistant Professor. Professor Lecturer Department of Pharmacognosy Professor Asst.
i) Basic degree in pharmacy (B. as the case may be. 3. iii) Master’s degree in appropriate branch of specialization in Pharmacy (M. iv) Ph. ii) Out of which five years must be as Assistant Professor.Pharm).D.86 iv) Ph. Director or Principal or Head of institute i) Fifteen years experience in Teaching or Research. . i) Ten years experience in Teaching or Research. Professor i) Basic degree in pharmacy (B.Pharm). iii) Master’s degree in appropriate branch of specialization in Pharmacy (M. Desirable : Administrative experience in responsible position.D. Note : If a class or division is not awarded at Master’s level. degree (with First Class degree either at Bachelor’s or Master’s level) in the appropriate branch of specialization in Pharmacy.D. 4. degree (with first Class either at Bachelor’s or Master’s level) in appropriate branch of specialization in Pharmacy. The maximum age for holding the post shall be 65 years. a minimum of 60% marks in aggregate or equivalent cumulative grade point average shall be considered equivalent to first class or division.Pharm). degree (with first Class degree either at Bachelor’s or Master’s level in the appropriate branch of specialization in Pharmacy. ii) Registration as a pharmacist under the Pharmacy Act. ii) Out of which five years must be as Professor or above in Pharmacy. ii) Registration as a pharmacist under the Pharmacy Act.Pharm) iv) Ph.
per week Assistant Professor – 12 hrs. per week Lecturers – 16 hrs. Pharm SSLC 3 4 5 1 1 1 Degree Degree D. b) Duration of training – Minimum 3 months.Pharm or a Bachelor degree recognized by a University or institution.87 v) Workload of Faculty : Professor – 8 hrs. 4) NON-TEACHING STAFF : Sl. BCA or Graduate with Computer Course Degree Degree SSLC ----- 6 Computer Data Operator Office Staff I Office Staff II Peon Cleaning personnel Gardener 1 7 8 9 10 11 1 2 2 Adequate Adequate . 1 2 Designation Laboratory Technician Laboratory Assistants or Laboratory Attenders Office Superintendent Accountant Store keeper Required (Minimum) 1 for each Dept 1 for each Lab (minimum) Required Qualification D.No. c) Training sites – Institutions running pharmacy practice or Programmes for atleast five years. per week vi) Training of Pharmacy Practice Faculty : a) Teaching staff will be trained as per the module prescribed by the Central Council. d) Trainer – Professor or Assistant Professor with minimum of five years of clinical pharmacy teaching and practice experience.
stores. Pharmacy Practice -2 -----Total = 8 -----In addition to the laboratories. staff. Phytochemistry or Pharmaceutical Chemistry -2 4. students common room. 6. staff common room. At least two lecture halls alongwith eight laboratories as specified below should be provided for: — 1. class rooms. animal house and a machine room shall also be provided. EQUIPMENT AND APPARATUS : Department wise list of minimum equipments A. Floor area of the laboratory should not be less than 30 square feet per student required to work in the laboratory at any given time subject to a minimum of 750 square feet. Life Science (Pharmacology. Gas and water fittings. DEPARTMENT OF PHARMACOLOGY : I. laboratories.88 5) ACCOMMODATION : Suitable and sufficient accommodation with adequate ventilation. 1 2 3 4 5 6 7 Name Microscopes Haemocytometer with Micropipettes Sahli’s haemocytometer Hutchinson’s spirometer Spygmomanometer Stethoscope Permanent Slides for various tissues Minimum required Nos. balance room. office. museum. 15 20 20 01 05 05 One pair of each tissue Organs and endocrine glands One slide of each organ system One model of each organ system One model for each organ system One set of skeleton and one spare bone 8 9 10 Models for various organs Specimen for various organs and systems Skeleton and bones . fuming cupboards be provided wherever necessary.No. Pharmaceutics and Pharmacokinetics Lab -2 2. shelves. lighting and other hygienic conditions should be provided to the rooms for Principal or the Head of the department. aseptic room or cabinet. Physiology. library. Pathophysiology) -2 3. Equipment: S. Laboratories should be fitted and constructed in a manner that these can be kept reasonably clean. etc.
Apparatus: S. DEPARTMENT OF PHARMACOGNOSY : I.26G Levers. B. Name 1 Microscope with stage micrometer 2 Digital Balance 3 Autoclave Minimum required Nos. 15 02 02 . 60 10 10 10 20 NOTE: Adequate number of glassware commonly used in the laboratory should be provided in each laboratory and department. Equipment: S.No 1 2 3 4 5 Name Folin-Wu tubes Dissection Tray and Boards Haemostatic artery forceps Hypodermic syringes and needles of size 15.24. cannulae Minimum required Nos.89 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 Different Contraceptive Devices and Models Muscle electrodes Lucas moist chamber Myographic lever Stimulator Centrifuge Digital Balance Physical /Chemical Balance Sherrington’s Kymograph Machine or Polyrite Sherrington Drum Perspex bath assembly (single unit) Aerators Computer with LCD Software packages for experiment Standard graphs of various drugs Actophotometer Rotarod Pole climbing apparatus Analgesiometer (Eddy’s hot plate and radiant heat methods) Convulsiometer Plethysmograph Digital pH meter One set of each device 01 01 01 01 01 01 01 10 10 10 10 01 01 Adequate number 01 01 01 01 01 01 01 II.No.
20 20 10 10 10 01 NOTE: Adequate number of glassware commonly used in the laboratory should be provided in each laboratory and department. 1 2 3 4 5 6 7 8 Name Hot plates Oven Refrigerator Analytical Balances for demonstration Digital balance 10mg sensitivity Digital Balance (1mg sensitivity) Suction pumps Muffle Furnace Minimum required Nos. C. 1 2 3 4 6 7 Name Reflux flask with condenser Water bath Clavengers apparatus Soxhlet apparatus TLC chamber and sprayer Distillation unit Minimum required Nos.D.No.O.incubator Refrigerator Laminar air flow Colony counter Zone reader Digital pH meter Sterility testing unit Camera Lucida Eye piece micrometer Incinerator Moisture balance Heating mantle Flourimeter Vacuum pump Micropipettes (Single and multi channeled) Micro Centrifuge Projection Microscope 02 01 01 01 02 01 01 01 15 15 01 01 15 01 02 02 01 01 II. Equipment: S. DEPARTMENT OF PHARMACEUTICAL CHEMISTRY : I. 05 03 01 05 10 01 06 01 .No. Apparatus: S.90 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 Hot air oven B.
80 Tablet punching machine Capsule filling machine Ampoule washing machine Ampoule filling and sealing machine Minimum required Nos. DEPARTMENT OF PHARMACEUTICS : I. 8. 10. Name 1 Distillation Unit 2 Reflux flask and condenser single necked 3 Reflux flask and condenser double/ triple necked 4 Burettes 5 Arsenic Limit Test Apparatus 6 Nesslers Cylinders Minimum required Nos. Equipment: S. 10 05 05 05 05 01 01 01 01 01 05 01 01 01 10 sets 01 01 01 01 .91 9 10 11 12 13 Mechanical Stirrers Magnetic Stirrers with Thermostat Vacuum Pump Digital pH meter Microwave Oven 10 10 01 01 02 II. 12. 66.24. D.22. Apparatus: S.No 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 Name Mechanical stirrers Homogenizer Digital balance Microscopes Stage and eye piece micrometers Brookfield’s viscometer Tray dryer Ball mill Sieve shaker with sieve set Double cone blender Propeller type mechanical agitator Autoclave Steam distillation still Vacuum Pump Standard sieves. 02 20 20 40 20 40 NOTE: Adequate number of glassware commonly used in the laboratory should be provided in each laboratory and department. sieve no. 44.No.
92 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 Tablet disintegration test apparatus IP Tablet dissolution test apparatus IP Monsanto’s hardness tester Pfizer type hardness tester Friability test apparatus Clarity test apparatus Ointment filling machine Collapsible tube crimping machine Tablet coating pan Magnetic stirrer. medium. 500ml and 1 liter capacity with speed control Digital pH meter All purpose equipment with all accessories Aseptic Cabinet BOD Incubator Bottle washing Machine Bottle Sealing Machine Bulk Density Apparatus Conical Percolator (glass/copper/ stainless steel) Capsule Counter Energy meter Hot Plate Humidity Control Oven Liquid Filling Machine Mechanical stirrer with speed regulator Precision Melting point Apparatus Distillation Unit 01 01 01 01 01 01 01 01 01 05 EACH 10 01 01 01 02 01 01 02 10 02 02 02 01 01 02 01 01 II. 15 15 05 20 05 each 01 05 03 10 NOTE: Adequate number of glassware commonly used in the laboratory should be provided in each laboratory and department.No 1 2 3 4 5 6 7 8 9 Name Ostwald’s viscometer Stalagmometer Desiccator* Suppository moulds Buchner Funnels (Small. large) Filtration assembly Permeability Cups Andreason’s Pipette Lipstick moulds Minimum required Nos. Apparatus: S. .
1 Orbital shaker incubator 01 2 Lyophilizer (Desirable) 01 3 Gel Electrophoresis 01 (Vertical and Horizontal) 4 Phase contrast/Trinocular Microscope 01 5 Refrigerated Centrifuge 01 6 Fermenters of different capacity 01 (Desirable) 7 Tissue culture station 01 8 Laminar airflow unit 01 9 Diagnostic kits to identify infectious 01 agents 10 Rheometer 01 11 Viscometer 01 12 Micropipettes (single and multi 01 each channeled) 13 Sonicator 01 14 Respinometer 01 15 BOD Incubator 01 16 Paper Electrophoresis Unit 01 17 Micro Centrifuge 01 18 Incubator water bath 01 19 Autoclave 01 20 Refrigerator 01 21 Filtration Assembly 01 22 Digital pH meter 01 NOTE: Adequate number of glassware commonly used in the laboratory should be provided in each laboratory and department. smooth muscle. 2 Adequate Adequate Adequate 1 Adequate 2 1 1 .No. kidney. F. pancreas.93 E. DEPARTMENT OF PHARMACEUTICAL BIOTECHNOLOGY : S.No.) 4 Watch glass 5 Centrifuge 6 Biochemical reagents for analysis of normal and pathological constituents in urine and blood facilities 7 Filtration equipment 8 Filling Machine 9 Sealing Machine Minimum required Nos.. liver etc. Name Minimum required Nos. Name 1 Colorimeter 2 Microscope 3 Permanent slides (skin. DEPARTMENT OF PHARMACY PRACTICE : Equipment: S.
10 11 12 13
14 1 15 1 16 1 17 Adequate 18 1 19 1 20 1 21 1 22 1 23 1 24 1 NOTE: 1. Computers and Internet connection (Broadband), six computers for students with internet and staff computers as required. 2. Adequate number of glassware commonly used in the laboratory should be provided in each laboratory and the department. G. CENTRAL INSTRUMENTATION ROOM : S.No. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 Name Colorimeter Digital pH meter UV- Visible Spectrophotometer Flourimeter Digital Balance (1mg sensitivity) Nephelo Turbidity meter Flame Photometer Potentiometer Conductivity meter Fourier Transform Infra Red Spectrometer (Desirable) HPLC HPTLC (Desirable) Atomic Absorption and Emission spectrophotometer (Desirable) Biochemistry Analyzer (Desirable) Carbon, Hydrogen, Nitrogen Analyzer (Desirable) Deep Freezer (Desirable) Ion- Exchanger Lyophilizer (Desirable) Minimum required Nos. 01 01 01 01 01 01 01 01 01 01 01 01 01 01 01 01 01 01
Autoclave sterilizer Membrane filter Sintered glass funnel with complete filtering assemble Small disposable membrane filter for IV admixture filtration Laminar air flow bench Vacuum pump Oven Surgical dressing Incubator PH meter Disintegration test apparatus Hardness tester Centrifuge Magnetic stirrer Thermostatic bath
1 1 Unit Adequate Adequate
(See regulation 16)
1) SPECIFIC OBJECTIVES : i) to provide patient care in cooperation with patients, prescribers, and other members of an interprofessional health care team based upon sound therapeutic principles and evidence-based data, taking into account relevant legal, ethical, social cultural, economic, and professional issues, emerging technologies, and evolving biomedical, pharmaceutical, social or behavioral or administrative, and clinical sciences that may impact therapeutic outcomes. ii) to manage and use resources of the health care system, in cooperation with patients, prescribers, other health care providers, and administrative and supportive personnel, to promote health; to provide, assess, and coordinate safe, accurate, and time-sensitive medication distribution; and to improve therapeutic outcomes of medication use. iii) to promote health improvement, wellness, and disease prevention in co-operation with patients, communities, at-risk population, and other members of an interprofessional team of health care providers. iv) to demonstrate skills in monitoring of the National Health Programmes and schemes, oriented to provide preventive and promotive health care services to the community. v) to develop leadership qualities to function effectively as a member of the health care team organised to deliver the health and family welfare services in existing socio-economic, political and cultural environment. vi) to communicate effectively with patients and the community. 2) OTHER DETAILS : i) All parts of the internship shall be done, as far as possible, in institutions in India. In case of any difficulties, the matter may be referred to the Pharmacy Council of India to be considered on merits. ii) Where an intern is posted to district hospital for training, there shall be a committee consisting of representatives of the college or university, and the district hospital administration, who shall regulate the training of such trainee. For such trainee a certificate of satisfactory completion of training shall be obtained from the relevant administrative authorities which shall be countersigned by the Principal or Dean of College.
iii) Every candidate shall be required, after passing the final Pharm.D. or Pharm.D. (Post Baccalaureate) examination as the case may be to undergo compulsory rotational internship to the satisfaction of the College authorities and University concerned for a period of twelve months so as to be eligible for the award of the degree of Pharm.D. or Pharm.D. (Post Baccalaureate) as the case may be.
3. ASSESSMENT OF INTERNSHIP : i) The intern shall maintain a record of work which is to be verified and certified by the preceptor (teacher practioner) under whom he works. Apart from scrutiny of the record of work, assessment and evaluation of training shall be undertaken by an objective approach using situation tests in knowledge, skills and attitude during and at the end of the training. Based on the record of work and date of evaluation, the Dean or Principal shall issue certificate of satisfactory completion of training, following which the university shall award the degree or declare him eligible for it. ii) Satisfactory completion of internship shall be determined on the basis of the following:(1) Proficiency of knowledge required for each case management SCORE 0-5 (2) The competency in skills expected for providing Clinical Pharmacy Services SCORE 0-5 (3) Responsibility, punctuality, work up of case, involvement in patient care SCORE 0-5 (4) Ability to work in a team (Behavior with other healthcare professionals including medical doctors, nursing staff and colleagues). SCORE 0-5 (5) Initiative, participation in discussions, research aptitude. SCORE 0-5 Poor 0 Fair 1 Below Average 2 Average 3 Above Average 4 Excellent 5
A Score of less than 3 in any of above items will represent unsatisfactory completion of internship.
It shall. the time-table for such examinations. The Examining Authority shall ensure that examiners for conducting examination for Pharm. (b) well-equipped laboratories for holding practical examinations. 5.D. and Pharm. It shall provide:(a) adequate rooms with necessary furniture for holding written examinations. if so required by a candidate. 4. It shall ensure that discipline and decorum of the examinations are strictly observed at the examination centers. and (d) such other facilities as may be necessary for efficient and proper conduct of examinations. (c) an adequate number of qualified and responsible examiners and staff to conduct and invigilate the examinations. the Examining Authority shall communicate to the Secretary. (Post Baccalaureate) programmes shall be persons possessing pharmacy qualification and are actually involved in the teaching of the Pharm.97 APPENDIX-D (See regulation 17) CONDITIONS TO BE FULFILLED BY THE EXAMINING AUTHORITY 1.D. 1948. and Pharm. It shall appoint examiners whose qualifications should be similar to those of the teachers in the respective subjects as shown in Appendix–B. 6. furnish the statement of marks secured by a candidate in the examinations after payment of prescribed fee. not less than six weeks in advance the dates fixed for examinations. It shall permit the Inspector or Inspectors of the Pharmacy Council of India to visit and inspect the examinations. to the Examining Authority. 3. (Post Baccalaureate) programmes in an approved institution.D. Pharmacy Council of India. In pursuance of sub–section (3) of section 12 of the Pharmacy Act. The Examining Authority shall be a statutory Indian University constituted by the Central Government/State Government/Union Territory Administration. 2. if any. (ARCHNA MUDGAL) Registrar-cum-Secretary Pharmacy Council of India New Delhi – 110002 . so as to enable the Council to arrange for inspection of the examinations. 7.D.
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