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Vpt 311 General and Systemic Veterinary Pharamacology Tanuvas Lect Notes

Vpt 311 General and Systemic Veterinary Pharamacology Tanuvas Lect Notes

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VPT 311 TANUVAS LECTURE NOTES
VPT 311 TANUVAS LECTURE NOTES

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Published by: Sunil on Sep 11, 2012
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03/10/2014

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•These are therapeutic agents produced through biotechnological means, but not by
conventional laboratory (chemical) synthesis.
•Biopharmaceuticals have their origin from the advancement in the knowledge of
biotechnology and molecular cell biology.
•Biopharmaceuticals popularly called as “Designer Proteins” are the promising therapeutic
tolls of the future.
•Examples are functional human peptides such as:
oADH, oxytocin, GnRH, ACTH, TSH/TRH, Calcitonin, Insulin, Somatostatin, Growth
Hormone, Cyclosporin etc., and
oEnzymes / proteins (Streptokinase, Asparaginase, DNAase, glucocerebrosidase,
erythropoietin, clotting factors, interferons, Monoclonal Antibodies, Vaccines etc)
Daclizumab(Zenopox).
•Genetically engineered human IgG (immunosuppressant monoclonal antibody binds
specifically to a-chain of IL2 receptor) used to lower the rate of rejection phenomenon in
kidney transplant recipients.
•Through DNA recombinant technology, bacteria are induced to produce hormones like
insulin and growth hormone and enzymes like L – asparaginase.

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