P. 1
Vpt421 Veterinary Toxicology Tanuvas Lecture Notes

Vpt421 Veterinary Toxicology Tanuvas Lecture Notes

5.0

|Views: 1,302|Likes:
Published by Sunil
VPT 421 TOXICOLOGY TANUVAS LECTURE NOTES
VPT 421 TOXICOLOGY TANUVAS LECTURE NOTES

More info:

Published by: Sunil on Sep 11, 2012
Copyright:Attribution Non-commercial

Availability:

Read on Scribd mobile: iPhone, iPad and Android.
download as DOC, PDF, TXT or read online from Scribd
See more
See less

10/28/2015

pdf

text

original

Iron is an essential mineral, but when a large amount is ingested, it can also be lethal.

Ingestion of 20 to 40 mg of elemental iron/kg of body weight may result in toxicosis.
Ingestion of > 60 mg/kg is potentially serious and oral dose of >200 mg/kg is roughly
estimated to be lethal. This kind of acute poisoning occurs primarily in dogs owing to, their
often indiscriminate eating habits.

Ingestion of large doses of soluble iron overwhelms the body’s protective defence
mechanism and results in free circulating iron, which causes severe tissue damage.

Sources

Iron is used as an anti-anaemic agent.

Injectable iron preparations include iron carbohydrate complex like iron-dextran or iron-
dextrin and oral preparations include ferrous sulphate, ferrous fumarate and lactate. Soluble
salts of iron pose the greatest risk of toxicosis.

38

It is available as over the counter (OTC) drug, in multivitamin mineral preparations and
gestational iron supplements. Since most of these preparations are sugar coated, dogs have
a tendency to swallow more tablets.

Iron is also used in fortified lawn and garden fertilizers.

You're Reading a Free Preview

Download
scribd
/*********** DO NOT ALTER ANYTHING BELOW THIS LINE ! ************/ var s_code=s.t();if(s_code)document.write(s_code)//-->