DRUG STUDY Name of the Drug Silver sulfadiazine (Thermazene) Classification Local anti-infectives Indication - To prevent or treat

wound infection in second and third degree burns Mechanism of Action A broad-spectrum sulfonamide that acts on cell membrane and cell wall; its bactericidal for many gram positive and gram negative organisms. Interactions Drug-drug. Topical proteolytic enzymes: may inactivate enzymes. Avoid using together. Drug-lifestyle. Sun exposure: may cause photosensitivity. Advise patient to avoid excessive sun exposure Adverse Reactions Hematologic: Leukopenia Metabolic: altered serum osmolality Skin: pain, burning, rash, pruritus, skin necrosis, skin discoloration. Nursing Consideration - Use sterile application technique to prevent wound infections. - Use drug only on a affected areas. Keep these areas medicated at all times. - Bathe patient daily, if possible. - inspect pt’s skin daily, and note any changes. Notify prescriber if burning or excessive pain develops. - Tell prescriber if hepatic or renal dysfunction occurs; drug may need to be stopped.

altering perception of and emotional response to pain. Drug-lifestyle: Alcohol use: may cause additive effect. urticaria.DRUG STUDY Name of the Drug Meperidine hydrochloride ( Demerol) Classification Opioid analgesic Indication . light-headedness CV: hypotension. somnolence. Phenytoin: May decrease meperidine level. Binds with opiate receptors in the CNS. ileus. dizziness. clouded sensorium. respiratory arrest Skin: pruritus. vomiting GU: urine retention Musculoskeletal: muscle twitching Respiratory: respiratory depression. bradycardia. diaphoresis Other: phlebitis after I. seizures. Give with full glass of water. Discourage use together.V. Nursing Consideration drug may be used in some patients who are allergic to morphine. Adverse Reaction CNS: sedation.Moderate to severe pain Mechanism of Action Unknown. Watch for decreased analgesia. - . cardiac arrest. shock GI: constipation. Syrup has local anesthetic effect. euphoria. nausea. Cimetidine: may increase respiratory and CNS depression. delivery Interaction Drug-drug. Monitor patient closely.

dizziness. diarrhea. rash. CV: edema. May inhibit prostaglandin synthesis to produce anti-inflammatory.urticaria Nursing Consideration .Monitor CBC and renal and hepatic function every 4 to 6 months during long term therapy.Serious GI toxicity. can occur in patient. analgesic and antipyretic effects. . palpitations EENT: tinnitus. vertigo. visual disturbances GI: epigastric pain.DRUG STUDY Name of the Drug Naproxen (Naprox) Classification Nonsteroidal antiinflammatory drugs Indications mild to moderate pain Mechanism of Action Unknown. . Hematologic: increased bleeding time Metabolic: Hyperkalemia Respiratory: dyspnea Skin: pruritus. drowsiness. heartburn. Adverse Reaction CNS: headache. including peptic ulcers and bleeding. nausea.

Adverse Reaction CNS: sedation. altering perception of and emotional response to pain. somnolence. biliary tract disease. - . vomiting GU: urine retention Musculoskeletal: muscle twitching Respiratory: respiratory depression. delivery Nursing Consideration Contraindicated in pt’s with GI obstruction. acute alcoholism. ileus. lightheadedness CV: hypotension. respiratory arrest Skin: pruritus. diaphoresis Other: phlebitis after I. shock GI: constipation. bradycardia. euphoria.DRUG STUDY Name of the Drug Morphine hyrochloride Classification Opioid analgesic Indication Severe pain Mechanism of Action Unknown. Binds with opiate receptors in the CNS. clouded sensorium. Use with caution in pt’s with circulatory shock. seizures. CNS depression. nausea. urticaria. dizziness.V. cardiac arrest.

Adverse Reaction CNS: seizure. give frequent mouth care fluids - .DRUG STUDY Name of Drug Mannitol (Osmitrol) Classification Diuretics Indication pulmonary edema edema of the airways Mechanism of Action Increases osmotic pressure of glomerular filtrate. urticaria Other: chills Nursing Consideration drug can be used to measure glomerular filtration rate. hypo and hypertension. rhinitis GI: thrist. headache. drug elevates plasma osmolality. To relieve thirst. Fever CV: edema. inhibiting tubular reabsorption of water and electrolytes. dry mouth. nausea. vomiting GU: urine retention Metabolic: dehydration Skin: local pain. increasing water flow into extracellular fluid. heart failure EENT: blurred vision.