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17 Pharmacy

17 Pharmacy

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Published by: king_007 on Oct 17, 2012
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Syllabus for FET – JNTUH - 2012

Subject Code : 17 Subject Name : Pharmacy Pharmaceutics: Formulation, Development, QC and storage of Tablets, Capsules and Pharmacokinetics and their importance in

Parenterals, Liquid dosage and semi solid dosage forms, Novel Drug delivery systems. Biopharmaceutics Pharmaceutical calculations. Study of physical properties of drugs: Practical size and shape, Pka solubility, partition coefficient, crystallinity, polymorphism and hygroscopicity. Study of chemical properties of drugs. Hydrolysis, oxidation, reduction, recimization. Polymerization and their influence on formulation and stability of drug products. Formulation and preparation of cosmetics lipstick, shampoo, creams, Nail preparations and dentifrices, pharmaceutical calculations. Pharmaceutical Analysis and Quality Assurance: Concepts of qualitative and

quantitative analysis, fundamentals of volumetric analysis, methods-of expressing concentration, primary and secondary standards: concept of error, precision, accuracy, specificity, sensitivity, detection limit, linearity and range. Ruggedness, standards, standardization, calibration of analytical equipments. Principles, instrumentation and applications of following: Absorption spectroscopy (UV, Visible & IR). Fluorimetry, Flame Photometry, potentiometry. Conductometry and polarography. Pharmacopoeia assays and chromatography methods. Quality assurance and quality control methods, concepts of GMP and GLP and forensic pharmacy. Principles of NMR, Mass spectroscopy, X-ray diffraction. Pharmaceutical Chemistry: Structure, nomenclature, classification, synthesis, SAR and metabolism of the following category of drugs, which are official in Indian Pharmacopoeia and British Pharmacopoeia. Stereochemistry of drug molecules. Hypnotics and Sedatives, Analysis, NSAIDS, Neuroleptics, Antidepressant, Anxiolytics, Anticonvulsants, Antihistaminics, Local Anesthetics, Cardio Vascular drugs - Antianginal agents Vasodilators, Adrenergic & Cholinergic drugs, Cardio tonic agent, Diuretics, Antihypertensive drugs, Hypoglycemic agents, Antilipedmic agents, Coagulants, Anticoagulants, Antiplatelet agents. Chemotherapeutic agent – -1-

Antibiotics,

Antibacterials,

Sulphadrugs.

Antiprotozoal

drugs,

Antiviral,

Antitubercular, Antimalarial, Anticancer, Antiamoebic drugs. Pharmacology: General Pharmacological Principles including Toxicology. Drug

interaction and pharmacology of drugs acting on central nervous system, cardiovascular system, Autonomic nervous system, Gastro intestinal system and Respiratory system. Pharmacology of Autacoids, Chemotherapeutic agents including anticancer drugs. Bioassays, Immuno Pharmacology. Drug acting on the blood & blood forming organs. Biochemistry: Biochemical role of hormones, Vitamins, Enzymes, Nucleic acids, Bioenergetics. General Principles of immunology. Immunological metabolism of carbohydrate, lipids, proteins. Methods to determine, kidney& liver function. Lipid profiles. Microbiology: Principles and methods of microbiological assays of the

Pharmacopoeia. Methods of preparation of official sera and Vaccines. Serological and diagnostics tests. Applications of microorganisms in Bioconversions and in Pharmaceutical industry. Pharmaceutical biotechnology: Isolation, classification and taxonomy of micro organisms. Pure culture techniques, theory and practice of sterilization, microbial growth phases and kinetics, microbial transformation of steroids. Fermentation technology: Batch and continuous fermentation. General characteristics and manufacture of antibiotics, vaccines and hormones. Application and scope of recombined DNA technology in manufacture of biological products such as insulin and human growth hormones. Biochemical role of hormones, vitamins, enzymes, nucleic acids, metabolic path ways: Glycoloysis and TCA cycle and transport across cell membranes. Pharmacognosy & Phytochemistry : Chemistry of natural products, tests, isolation, characterization and estimation of phytopharmaceuticals belonging to the group of Alkaloids, Glycosides, Terpenoids, Steroids; Bioflavonoids, Purines, Guggul lipids, proteins. Pharmacognosy of crude drugs that contain the above constituents and -2-

herbal products alternate system of medicine like Ayurveda,Unani, Homeopathy, Sidda, Naturopathy Etc., Standardization of raw materials and herbal products. WHO guidelines. Quantitative microscopy including modern techniques used for evaluation. Biotechnological principles and techniques for plant development, tissue culture. Pharmaceutical Jurisprudence: Drugs and cosmetics Act and rules with respect to manufacture, sales and storage. Pharmacy act. Pharmaceutical ethics.

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