Large cell acanthoma

Deba P Sarma, MD Omaha

Large cell acanthoma

Clinical: Middle aged or older adults. -Sharply demarcated patch on head and neck, trunk and limbs.

Pathology: -Basket-weave hyperkeratosis, hypergranulosis, flat-topped papillomatosis and rounded acanthosis. -The keratinocyres of the lesion are larger with larger nuclei compared to the adjacent epidermis. -The lesion is sharply demarcated from the adjacent epidermis.

Sign up to vote on this title
UsefulNot useful