Basic Computation/s Part II IV Drugs & IVF Chapter 4

Interpretation/Calculati ng Medication Dosages

Ratio – is the relationship of two quantities
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1:10 , 1:2500 1/10 , 1/2500

Interpretation/Calculati ng Medication Dosages

RATIO e.g For every 20 students there is 1 teacher. The ratio of teacher to students is 1 in 20 or 1:20 or 1/20

Interpretation/Calculati ng Medication Dosages    Proportion – formed by using two ratios that are equal 1 = 5 = 2 x 5 = 10 x 1 2 10 Cross products are equal to  10 = 10  ½ is equal to 5/10 .

Proportion  Dose ¼ = 3/12  Cross products are 12 = 12 ¼ = 3/12  .

20 mg is the desired . How many ml will be needed to supply the dose of 20 mg? Given: 1.Example:     The Md orders 20 mg IM of a drug for a patient. The drug is available in 10 ml vial that contains 50 mg of drug. 50 mg of drug in 10 ml vial 3. 10 ml vial 2.

   Ratio 10ml = 1ml 50mg 5mg Ratio for the required dose    x ml 20 mg Proportion: 1ml = x ml 5mg 20 mg 5 x x = 1 x 20 5x = 20 x = 4ml ( 20 divided by 5 ) .Cont.

250mg/5ml . 1.Example/s:. How many ml would be measured into a medication syringe to obtain a dose of 75mg of ampicillin? . Ampicillin oral susp.

Paracetamol 125mg/ 5ml. How many ml would be measured into a medication syringe to obtain 15 mg of Paracetamol? .Example/s  2.

Example/s  3. How many ml of Paracetamol IV should be given to obtain a dose of 15mg in a 15kg-man. if a vial contains 300mg/2ml of Paracetamol? .

6 ml of this solution? .Example/s  4. A vial contains 250mg of tetracycline HCl in a total of 2 ml of solution. How many mg of tetracycline HCl are contained in 0.

Conversion Between Systems of measurement      1000 g 1000 mg 1000 ng 1000 ml 100 ml = = = = = 1 1 1 1 1 kg g mcg L dL .

Conversion Between Systems of measurement    Rule: 1 To convert a quantity in the metric system to a large metric unit (mg to g) move the decimal point to the left Smaller to larger =right to left Example: 2mg = 0.002g  .

4 l = 2400 ml .Conversion Between Systems of measurement    Rule: 2 To convert a quantity to a smaller metric unit. move the decimal point to the right Example: 2.

Examples   Convert 25 g to mg Convert 150 ml to liters .

1/150 gr Approximate equivalent 15 grains = 1 gram  1grain = 60 mg  . 1/150 gr Atropine sulfate 1/200gr. which is the smallest unit in the system Nitroglycerin 1/100gr.Apothecary System of weights     based upon the grain.

Apothecary System of weights  Convert 15 milligrams to grains 1 grain = x grain 60 mg 15 mg 60 x = 15 x = 15/60 x = .25 grain    .

Example: The physician orders 7 ½ grains of aminophylline po for a client.5 g (500mg)    .5 grain 15 x = 7.5 x = 0. On hand are aminophylline tablets 500 mg. How many tablets are required for one dose? GIVEN: 1 gram = x gram 15 grain 7.

4 mg .0067 x = 0.0004g = 0.Example:       How many mg of nitroglycerin are in one 1/150 grain tablet of the drug? Given: 1 gram = x gram 15 grains 1/150 grains 15 x = 1/150 = .

Calculation of Fractional Doses:  ratio and proportion .

000 units/ml  250. 000.000 units = 1.Example: The Md orders 1.000 units of Pen G for a patient. The pen G on hand is available as a solution containing 250.000 units 1 ml x ml  250.000  x = 4 ml .000x = 1.000.000.

How many ml should be given to the patient? .000mcg/ml. The vitamin on hand is labeled 1.Example 1:  The physician orders 250 mcg of Vitamin B12 IM daily.

Example 2:  A patient is to be given 25 mg Diphenhydramine po and is available as 12.5mg/5ml prep.. How many ml should be given? .

On hand are tablets of calcium lactate 0.5 g.Example 3:  A medication order calls for 750 mg calcium lactate to be given TID PO. How many tablets should be given for each dose? .

How many 500 mg tablets should be given to this patient for each dose. The recommended dosage is 20 mg/kg/dose. .Calculation of Dosages Based on Weight  The physician orders thiabendazole chewable tablets for a 110 pound child.

Calculation of Dosages Based on Weight        Convert weight to kg 20 mg = x mg 1 kg 50 kg x = 1000 mg 500 mg = 1000mg 1 tab x tab x = 2 tablets per dose .

Example:  The recommended dose of Meperidine is 6mg/kg/day for pain. How many ml of Demerol injection 50mg/ml should be administered to a 33 pound child as a single dose every 6 hours? . It is given every 4 to 6 hours.

Cont.  Calculate the daily dose for a 33pound child 6mg/ 1 kg (2.2lb) = x mg / 33 lb x = 90 mg Demerol / day   .

 Calculate the number of ml of demerol injection 50 mg/ml needed for the daily dose 50 mg/ 1 ml = 90 mg/ x ml  .Cont.

Cont.8 x = 0.8 ml/ 24 h = x ml/ 6 h 24 x = 10.45 ml .     Calculate the number of ml to be given every 6 hours 1.

5 L of D5 W being administered at the rate of 45 drops /min? The IV set is calibrated to deliver 15 drops/ml.Calculations Involving Intravenous Administration  How long will it take to complete an IV infusion of 1. .

Calculations Involving Intravenous Administration    Determine the number of ml/min being infused Drop rate of IV set = 15 gtt/1ml = 45gtt/ x ml  15 x = 45  x = 3 ml/min .

Calculations Involving Intravenous Administration Calculate the number of ml/hour 3 ml/min. x 60 min/hr = 180/ hour .

500 x = 8. If 180 ml are delivered each hour.500 ml?    180ml/hr = 1.3 hours or 8 hours 20 min.500 ml/hr 180 x = 1. . then how many hours are required to administer 1.Calculations Involving Intravenous Administration  Calculate the number of hours required to administer the total volume of the solution.

ml. should be administered? . The piggyback IV set is calibrated to deliver 10 gtts.Calculations Involving Piggyback IV Infusion  An IV piggyback of Cefazolin 500mg in 100ml/hour is ordered. How many drops/min.

/ 1min. Flow rate: Drop rate 10 gtt/ min. 60 x = 100 x = 1.7 ml/ min. = x gtt/ 1. = x ml/ min.Calculations Involving Piggyback IV Infusion        100 ml/ 60 min.7 ml X = 17 gtt/ min. .

Calculations Involving Piggyback IV Infusion   Daily fluid requirement 2000ml of electrolyte solution administered 24 hours and that Cefazolin sodium 500 mg in 100 ml/hr is ordered QID. The number od ml/day and the times of the piggybank infusion must be subtracted from the daily fluid requirement. .