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THREE-YEAR FULL-TIME PROGRAMME (Six-Semester Course)
(Effective from the Academic Year 2010-2011)
UNIVERSITY OF DELHI DELHI – 110 007
PART I: Semester – 1 Paper 1 Paper 2 Paper 3 Paper 4 CHPT 101 LSPT 101 MACT 303 ENAT 101*/ CSAT 101* Chemistry-I Biology-I (Introduction to Biology) Mathematics and Statistics Technical writing and Communication in English / Computational skills
PART I: Semester – 2 Paper 5 Paper 6 Paper 7 Paper 8 CHPT 202 LSPT 202 LSPT 203 ENAT 201*/ CSAT 201* Chemistry -II Biology-II Food, Nutrition and Health Technical writing and Communication in English / Computational skills
*The college will have an option to take either of the two papers in a particular semester for a particular course, while students have to appear in both the papers In addition, there shall be one qualifying paper in self-learning mode called Environmental Studies offered in Semester-2
PART II: Semester – 3 Paper 9 Paper 10 Paper 11 Paper 12 CHPT303 LSPT 304 LSPT 305 LSPT 306 Chemistry -III Biodiversity-I “Microbes” Biodiversity-II “Animals” Introduction to Medical Diagnostics
PART II: Semester – 4 Paper 13 Paper 14 Paper 15 Paper 16 CHPT 404 LSPT 407 LSPT 408 LSPT 409 Chemistry –IV Molecular Biology Biodiversity-II “Plants” Bioinformatics
PART III: Semester – 5 Paper 17 Paper 18 Paper 19 Paper 20 CHPT 505 LSPT 510 LSPT 511 LSPT 512 Chemistry –V Biochemistry and Immunology Developmental Biology and Physiology-Plants Genetics & Genomics
PART III: Semester – 6 Paper 21 Paper 22 Paper 23 Paper 24 CHPT 606 LSPT 613 LSPT 614 LSPT 615 Chemistry –VI Applied Biology and Biotechnology Developmental Biology and Physiology-Animals Ecology and Environmental Management
The ongoing B.Sc. Life Sciences course was introduced by the Faculty of Science from the academic year 2005-2006. Broadly, the same course has now been changed to semester-based scheme and shall be effective from the current academic year 2010-2011. However, the opportunity presented by the semester-based scheme has been used for some revision to accommodate the widening horizons of the discipline of biological sciences. Specifically, the subjects on computational skills and bioinformatics have been included so that students can keep pace with the new and expanding information in the field. Two new disciplines: “Food, Nutrition and Health” in Semester II and “Introduction to Medical Diagnostics” in Semester III have been introduced to provide better employment opportunities to Graduate students. In addition, six papers of chemistry covering almost major streams of chemical sciences that should be taught to biology students have also been included. The course content also lists new practical exercises, especially in molecular biology so that the students get a hands-on experience of the latest techniques that are in current usage both in the advanced research laboratories and in Industry.
Paper 1-CHPT 101- Chemistry-1 (Atomic Structure, Bonding, General Organic Chemistry & Aliphatic Hydrocarbons)
Section A: Inorganic Chemistry-1
Unit 1. Atomic Structure: Recapitulation of: Bohr’s theory and its limitations, dual behaviour of matter and radiation, de-Broglie’s relation, Heisenberg Uncertainty principle. Need of a new approach to Atomic structure. What is Quantum mechanics? Time independent Schrodinger equation (H Ψ = EΨ) and meaning of various terms in it. Significance of Ψ and Ψ2, Schrodinger equation for hydrogen atom in Cartesian coordinates (x,y,z). Need of polar coordinates, transformation of Cartesian coordinates (x,y,z) into polar coordinates (r,θφ). Radial and angular parts of the hydogenic wavefunctions (atomic orbitals) and their variations for 1s, 2s, 2p, 3s, 3p and 3d orbitals. (Only graphical representation), Radial and angular nodes and their significance. Radial distribution functions and the concept of the most probable distances with special reference to 1s and 2s atomic orbitals. Significance of quantum numbers, orbital angular momentum and quantum numbers mr and ms. Shapes of s, p and d atomic orbitals, nodal planes. Discovery of spin, spin quantum number (s) and magnetic spin quantum number (ms). Rules for filling electrons in various orbitals, Electronic configurations of the atoms. Stability of half-filled and completely filled orbitals, concept of exchange energy. Relative energies of atomic orbitals, Anomalous electronic configurations. Unit 2. Chemical Bonding and Molecular Structure Ionic Bonding :General characteristics of ionic bonding. Energy considerations in ionic bonding, lattice energy and solvation energy and their importance in the context of stability and solubility of ionic compounds. Statement of Born-Lande equation for calculation of lattice energy, Born-Haber cycle and its applications, polarizing power and polarizability. Fajan’s rules, ionic character in covalent compounds, bond moment, dipole moment and percentage ionic character. Covalent bonding :VB Approach :Shapes of some inorganic molecules and ions on the basis of VSEPR and hybridization with suitable examples of linear, trigonal planar, square planar, tetrahedral, trigonal bipyramidal and octahedral arrangements. Concept of resonance and resonating structures in various inorganic and organic compounds. MO Approach : Rules for the LCAO method, bonding and antibonding MOs and their characteristics for s-s, s-p and p-p combination of atomic orbitals, non- bonding combination of orbitals ,MO treatment of homonuclear diatomic molecules of 1st and 2nd periods (including idea of s-p mixing) and heteronuclear diatomic molecules such as CO, NO and NO+. Comparison of VB and MO approaches.
D and L. Interconversion of Wedge Formula. Concept of chirality (upto two carbon atoms). Wurtz reaction. hydroboration-oxidation. from Grignard reagent. Alkynes: (Upto 5 Carbons) Preparation: Acetylene from CaC2 and conversion into higher alkynes. Configuration: Geometrical and Optical isomerism. Newman.r. Diastereomerism and Meso compounds) . dehydrohalogenation of vicinal-dihalides. Reactive Intermediates: Carbocations. ethane. Unit 5. Electronic Displacements: Inductive Effect.Section B: Organic Chemistry-1 (30 Periods) Unit 3. Unit 4. Reactions: cis-addition (alk. Ozonolysis. ozonolysis and oxidation with hot alk. by dehalogenation of tetra halides.trans nomenclature. Enantiomerism.t. oxymecuration-demercuration. 5|Page . CIP Rules: R/ S (for upto 2 chiral carbon atoms) and E / Z Nomenclature (for upto two C=C systems). cis alkenes (Partial catalytic hydrogenation) and trans alkenes (Birch reduction). Aliphatic Hydrocarbons Functional group approach for the following reactions (preparations & reactions) to be studied in context to their structure. Reactions: formation of metal acetylides. Addition of HX (Markownikoff’s and anti-Markownikoff’s addition). KMnO4. Hydration. Fundamentals of Organic Chemistry Physical Effects. addition of bromine and alkaline KMnO4. Aromaticity: Benzenoids and Huckel’s rule. shape and reactivity of organic molecules : Nucleophiles and electrophiles. Structure. cis . Alkanes:(Upto 5 Carbons). Cleavage of Bonds: Homolysis and Heterolysis. Alkenes: (Upto 5 Carbons) Preparation: Elimination reactions: Dehydration of alkenes and dehydrohalogenation of alkyl halides (Saytzeff’s rule). Strength of organic acids and bases: Comparative study with emphasis on factors affecting pK values. Reactions: Free radical Substitution: Halogenation. Resonance and Hyperconjugation. Carbanions free radicals. Sawhorse and Fischer representations. Preparation: Catalytic hydrogenation. Threo and erythro. Stereochemistry Conformations w. Electromeric Effect. butane and cyclohexane. Kolbe’s synthesis. KMnO4) and trans-addition (bromine).
Chemistry-1 (Atomic Structure. E. R. L. Estimation of sodium carbonate and sodium hydrogen carbonate present in a mixture. Orient Longman. James E. Peter Sykes: A Guide Book to Mechanism in Organic Chemistry. I & II). Chand 4. Section B: 1. Bahl : Advanced Organic Chemistry. S. L. 2. 3. Detection of extra elements (N. Estimation of oxalic acid by titrating it with KMnO4. J. 4. T. Huheey. B. Morrison & R.SUGGESTED READINGS Section A: 1. Bonding. I. Pearson Publication. Prentice Hall. Marks: 50 Section B: Organic Chemistry 1. 2. D. Boyd: Organic Chemistry. glutamic acid. S. tyrosine or any other amino acid) by paper chromatography (b) Identify and separate the sugars present in the given mixture by paper chromatography. Separation of mixtures by Chromatography: Measure the Rf value in each case (combination of two compounds to be given) (a) Identify and separate the components of a given mixture of 2 amino acids (glycine. Finar : Organic Chemistry (Vol.S. 3. Estimation of Cu(II) ions iodometrically using Na2S2O3. Ellen Keiter and Richard Keiter : Inorganic Chemistry: Principles of Structure and Reactivity. aspartic acid. Lee: A new Concise Inorganic Chemistry. N. Arun Bahl and B.Br. 5. Estimation of water of crystallization in Mohr’s salt by titrating with KMnO4. 6|Page . E L. CHPP 101. Estimation of Fe(II) ions by titrating it with K2Cr2O7 using internal indicator. S. General Organic Chemistry & Aliphatic Hydrocarbons) PRACTICALS Section A: Inorganic Chemistry . 2.Cl. S. B.I) in organic compounds (containing upto two extra elements) 2.Volumetric Analysis 1.
Detecting macromolecules of genetics. Biology and everyday life b. Structure of an atom. Variation on Mendel’s Law. Darwinian view of life and origin of species (Ch22. A closer look at cell. Properties of water. Biological systems. The energy level of electron. Phylogeny and the tree of life c. A closer look at ecosystem. Genetic approach to Biology (Ch 1 Griffiths) (8 Periods) Patterns of inheritance and question of biology. Mechanism of Macroevolution. Classifying the diversity of life Kingdoms of Life –Prokaryotes. Mechanism of speciation e. Introduction to concepts of biology (Ch 1 Campbell) (4 Periods) Marks: 100 Themes in the study of biology. Genetic Variation. Developmental noise. The process of Science. What makes carbon special? Properties of organic compounds 7|Page .Paper 2-LSPT 101. Evolutionary history of biological diversity (Ch 25 Campbell) (6 Periods) Early earth and the origin of life. Model organisms for the genetic analysis. The formation and function of molecules depend on chemical bonding between atoms. Water and life The water molecule is polar. Concepts of species.BIOLOGY-I (INTRODUCTION TO BIOLOGY) THEORY Unit 1. Major events in the history of life. Chemistry of life (Ch 2 Campbell) (6 Periods) The constituents of matter. Eukaryotes. Methodologies used to study genes and gene activities. The flow of genetic information from DNA to RNA to protein. Chemical context of living systems a. evolution and biodiversity a. Distinction between Phenotype and Genotype Unit 2. Chemical reaction make or break chemical bonds b. Carbon and life (Ch 4 Campbell) (5 Periods) (Ch 3 Campbell) (5 Periods) Organic chemistry-the study of carbon compounds. The molecular basis of genetic information. Ionization of water c. The evolution of populations. Archaea d. 24 Campbell) (10 Periods) (Ch 25 Raven) (8 Periods) Darwin’s theory of evolution.
Freeman & Co. To raise the culture of E. Raven. Pearson Benjamin Cummings. 8|Page . San Francisco. To separate and quantify sugars by thin layer chromatography. To perform quantitative estimation of protein using the Lowry's method. N. Campbell. coli. 5. Nucleic acids store and transmit hereditary information SUGGESTED BOOKS 1.d. 7. molar and standard solutions. phosphate buffers.A. To perform gram staining of bacteria. 4. Protein have diverse structures and functions. 2. 3. W. B. New Delhi 3. coli and estimate the culture density by turbidity method. P. serial dilutions Use of micropipettes Separation of A) amino acids B) chloroplast pigments by paper chromatography. 2. 9. and Reece. Isolation of genomic DNA from E.F et al (2008) Introduction to Genetic Analysis. J. Structure and function of biomolecules (Ch 5 Campbell) (8 Periods) Most macromolecules are Polymers. (2008) Biology 8th edition. 8. NY LSPP 101.J. Marks: 50 To learn a) use of microscope b) principles of fixation and staining. 9th edition. Preparation of Normal. 10. Carbohydrates act as fuel and building materials.H et al (2006) Biology 7th edition Tata McGrawHill Publications.H. To study the cytochemical distribution of nucleic acids and mucopolysaccharides with in cells/tissues from permanent slides. Determine the concentration of the unknown sample using the standard curve plotted. 6. A. Draw a growth curve from the available data. Lipids are group of hydrophobic molecules. Griffiths.BIOLOGY-I (INTRODUCTION TO BIOLOGY) PRACTICALS 1.
Emphasis on examples from Biological Sciences. Motivation and illustration for these functions through projectile motion. Use of methods of differentiation like Chain rule. simple pendulum. Examples of matrices inducing Dilation. Hypothesis testing using standard normal variate.Paper 3-MACT 303-MATHEMATICS AND STATISTICS Marks: 100 Unit 1. (24 Periods) Sets. Differentiation. Elementary Probability and basic laws. Product rule and Quotient rule. Discrete and Continuous Random variable. Step function. kurtosis. continuity and limits. Correlation and Regression. Sum and Produce of matrices upto order 3. Unit 3. Conception to be motivated through simple concrete examples as given above from Biological and Physical Sciences. Infinite Geometric Series. Integrals of the functions introduced above. Curve Fitting. (14 Periods) Points in plane and space and coordinate form. Simple observations about these functions like increasing. muscular fibres etc. Intuitive idea of algebraic relationships and convergence. cos x. Rotation. Examples of matrices arising in Physical. sine. Measures of dispersion. sin x. log (1+x). exponential and logarithmic functions. Mean and Variance of Binomial. Poisson and Normal distribution. Sample mean and Sampling variance. 9|Page . Integration as reverse process of differentiation. Series formulas for ex. Mathematical Expectation. Functions and their graphs : polynomial. Unit 2. Reflection and System of linear equations. For instance. biological rhythms. Intuitive idea of discontinuity. the Fibonacci sequence arising from branching habit of trees and breeding habit of rabbits. cell division. cosine. Biological Sciences and Biological networks. followed by concepts of recursion and difference equations. Second order derivatives of above functions. periodicity. Sequences to be introduced through the examples arising in Science beginning with finite sequences. (20 Periods) Mesures of central tendency. decreasing and. skewness.
1975) 3. Danial : Biostatistics : A foundation for Analysis in Health Sciences. Oxford University Press. John Wiley and Sons Inc. graphical and application oriented approaches. International Student Edition. S. Druce : Advanced Biology Statistics. W. Edmondson and D. Batschelet : Introduction to Mathematics for Life Scientists. New Delhi (1971. 10 | P a g e . Bear: Understanding Calculus. 2003. 2004. E.SUGGESTED READINGS 1. H. Narosa Publishing House. A. 4. 2.Springer Verlag. Note: It is desirable that softwares should be used for demonstrating visual. 1996. John Wiley and Sons (Second Edition).
distinct features of speech. notices. Riordan & Steven A. London. transitional and concluding paragraphs. minutes. Biztantra: Technical Report Writing Today. formal writings/reports. developing the thesis. differences between speech and writing. 4. Selection of topic. Unit 2 Writing Skills. Riordan. L. coherence and cohesion. Frank. Daniel G. S. distinct features of writing. Biztantra. Svartik: A comprehensive grammar of the English language. Unit 3 Technical Writing: Scientific and technical subjects. 5th Edition (2004). 2. handbooks. manuals. Hamp-Lyons and B.Biztaantra. Press. narrative. 8th Edition (2004). G. Leech and J. R. letters. Daniel G. Quirk. 11 | P a g e . thesis statement. Prentice Hall Reagents. formal and informal writings. Steven E. M. Scot Ober. linguistic unity. descriptive. Longman. 6. Heasely: Study Writing. Additional Reference Books 5.Paper 4/8-ENAT 101/201-TECHNICAL WRITING AND COMMUNICATION IN ENGLISH Marks: 100 Unit 1 Communication: Language and communication. memorandum. Englewood Cliffs. Greenbaum. introductory. Pauley. SUGGESTED READINGS 1. Panley: “Technical Report Writing Today” . Cambridge Univ. expository and argumentative writing. developmental. 3. agenda. common errors to be avoided. For academic and professional purposes. A course in written English. Contemporary Business Communication. Writing as thinking: A guided process approach.
PHI. developing macros in spreadsheet General Awareness (4 Periods) IT Act. stepwise methodology of developing an algorithm. Reference manual for Open Office available at: http://www. 1's Complement. Reservations. BCD. ASCII.openffice. Elements. Characteristics. 2's Complement. switch. Applications Problem Solving (10 Periods) Notion of algorithms. Addition and subtraction of binary numbers. memory hierarchy. as they are freely downloadable. Note: Use of Open Office/Star Office is recommended.org Star Office available at: http://www.Units of a computer. Types and generations of Computers Basic Computer Organization . Uses of computers. I/O devices User Interface with the Operating System.sun. Banking SUGGESTED BOOKS  V Rajaraman. System Tools Data Representation (8 Periods) Binary representation of integers and real numbers. registers. Fundamentals of Computers.com/software/staroffice/ 12 | P a g e . ALU. System Security (virus/firewall) I-Tax. router. CPU. server-client architecture Multimedia (4 Periods) Introduction. Unicode. Fourth Edition. Networks terminology (4 Periods) Types of networks.Paper 4/8-CSAT 101/201-COMPUTATIONAL SKILLS THEORY Computer Fundamentals (12 Periods) Marks: 100 Introduction to Computers: Characteristics of Computers.
Familiarizing with the Operating System. 2. Presentation Software Marks: 50 4. 13 | P a g e . basic functions and formulas. Document Preparation 3. creating charts. Control Panel. entering and formatting information. Working with worksheets. Creating a spreadsheet. Networking Configuration. Firewall setting 5. Spreadsheet Handing.CSAP 101/201-COMPUTATIONAL SKILLS PRACTICALS 1. tables and graphs. Defined projects will be done by the students and evaluated by the instructor.
Salt hydrolysis-calculation of hydrolysis constant. bond dissociation energy and resonance energy from thermochemical data. Calculations of entropy change and free energy change for reversible and irreversible processes under isothermal and adiabatic conditions. Calculation of bond energy. ionization constant and ionic product of water. Criteria of spontaneity. degree of hydrolysis and pH for different salts. Thermodynamic derivation of the law of chemical equilibrium. state variables. Le Chatelier’s principle. heat (q). Statement of Third Law of thermodynamics and calculation of absolute entropies of substances. Chemical Equilibrium Free energy change in a chemical reaction. Relationships between Kp.Paper 5-CHPT 202. moderate and weak electrolytes. changes in internal energy (∆U) and enthalpy (∆H) for expansion or compression of ideal gases under isothermal and adiabatic conditions for both reversible and irreversible processes. concept of entropy. pH scale. concept of heat and work. Gibbs free energy and Helmholtz energy. Unit 2. intensive and extensive variables. First Law of thermodynamics. factors affecting degree of ionization. Ionic Equilibria Strong. 14 | P a g e . common ion effect.Chemistry-2 (Thermodynamics. thermodynamic properties. various types of systems and processes. ∆U and ∆H for processes involving changes in physical states. q. thermodynamic equilibrium. Buffer solutions. Gibbs – Helmholtz equation. degree of ionization. Distinction between ∆G and ∆Gѳ. integral and differential enthalpies of solution and dilution. Various statements of Second Law of thermodynamics. Calculation of w. Variation of enthalpy of a reaction with temperature – Kirchhoff’s equation. Equilibria & Functional Group Organic Chemistry-1) THEORY Section A: Physical Chemistry-1 Marks: 100 (30 Lectures) Unit 1. Concept of standard state and standard enthalpies of formations. Unit 3. Maxwell’s relations. Ionization of weak acids and bases. Kc and Kx for reactions involving ideal gases. Important principles and definitions of thermochemistry. Calculation of work (w). Chemical Thermodynamics What is thermodynamics? State of a system. Solubility and solubility product of sparingly soluble salts – applications of solubility product principle.
by decarboxylation. alk. NH2-G derivatives. Houben – Hoesch Condensation. Benzoin condensation. from benzene sulphonic acid. bromo and iodo-benzene case): from phenol. Aldehydes and ketones (aliphatic and aromatic): (Formaldehye. Wittig reaction. ROH. Reduction of aldehydes. con. from diazonium salts. halogenation and sulphonation. Aromatic hydrocarbons Preparation (Case benzene): from phenol. acetone and benzaldehyde) Preparation: from acid chlorides and from nitriles. Preparation: from alkenes and alcohols.Section B: Organic Chemistry-2 (30 Lectures) Functional group approach for the following reactions (preparations & reactions) to be studied in context to their structure. Reactions: hydrolysis. Iodoform test. acid. halogenation and sulphonation. Cannizzaro’s reaction. Aryl Halides Preparation: (Chloro. Phenols: (Phenol case) Preparation: Cumene hydroperoxide method. Aldol Condensation. oxidation (with PCC. (Upto 4 carbons on benzene). Reactivity and Relative strength of C-Halogen bond in alkyl. Phenols and Ethers (Upto 5 Carbons) Alcohols: Preparation: Preparation of 1 3 alcohols: using Grignard reagent. acetaldehyde . Reactions – Reaction with HCN. Reactions : (Case benzene) : Electrophilic substitution: nitration. NaHSO3. Gattermann-Koch Reaction. Benzyne Mechanism: KNH2/NH3 (or NaNH2/NH3). benzyl. allyl. carboxylic acid and esters. Sandmeyer & Gattermann reactions. from acetylene. Unit 6. Unit 5. HX (Lucas test). vinyl and aryl halides. Alcohols. 15 | P a g e . Reactions: Electrophilic substitution: Nitration. Unit 7. dichromate. Reactions (Chlorobenzene): Aromatic nucleophilic substitution (replacement by –OH group) and effect of nitro substituent. Unit 4. Oppeneauer oxidation Diols: (Upto 6 Carbons) oxidation of diols. Friedel-Craft’s reaction (alkylation and acylation). esterification. Reactions: With sodium. Pinacol-Pinacolone rearrangement. Meerwein-Pondorff Verley reduction. Williamson’s ether synthesis: Elimination vs substitution.Tiemann Reaction. ketones. Schotten – Baumann Reaction Ethers (aliphatic and aromatic): Cleavage of ethers with HI. Reimer . SN1 and SNi) reactions. nitrite & nitro formation. Side chain oxidation of alkyl benzenes (Upto 4 carbons on benzene). HNO3). nitrile & iso-nitrile formation. Ester hydrolysis. KMnO4. Alkyl and Aryl Halides Alkyl Halides (Upto 5 Carbons) Types of Nucleophilic Substitution (SN2. Clemensen reduction and Wolff Kishner reduction.
Determination of enthalpy of hydration of copper sulphate. Arun Bahl and B. T. Determination of heat capacity of calorimeter for different volumes. L. Castellan. Finar : Organic Chemistry (Vol.Chemistry-2 (Thermodynamics. CHPP 202. S. Boyd : Organic Chemistry. Determination of integral enthalpy of solution of salts (KNO3. W. (a) Bromination of Phenol/Aniline (b) Benzoylation of amines/phenols (c) Oxime and 2. University Chemistry 3rd Ed. 6. determination of melting point and calculation of quantitative yields to be done. Narosa (1998). L. Prentice Hall. I. 2. Bahl : Advanced Organic Chemistry. G. 5. N. Physical Chemistry 4th Ed. Orient Longman. 2) Criteria of Purity: Determination of melting and boiling points.4 dinitrophenylhydrazone of aldehyde/ketone 16 | P a g e Marks: 50 . 2. Determination of enthalpy of neutralization of hydrochloric acid with sodium hydroxide. Equilibria & Functional Group Organic Chemistry-1) PRACTICALS Section A: Physical Chemistry Thermochemistry 1. Mahan. R. Determination of enthalpy of ionization of acetic acid. Morrison & R. 3. Recrystallisation. Section B: Organic Chemistry 1) Purification of organic compounds by crystallization (from water and alcohol) and distillation.SUGGESTED READINGS Section A: 1 Barrow. Section B: 1. G. S. 3) Preparations: Mechanism of various reactions involved to be discussed. NH4Cl). B. Peter Sykes : A Guide Book to Mechanism in Organic Chemistry. Study of the solubility of benzoic acid in water and determination of ∆H. H. I & II). 3. 2. S. Narosa (2004). 3. E. B. M. Physical Chemistry Tata McGraw‐Hill (2007). 4. Chand 4.
Symbiont hypothesis.Paper 6-LSPT 202-BIOLOGY-II THEORY Cell and Cellular Processes Unit 1. Faces of the membranes. Eukaryotic Cell components Unit 3. The fluidity of membranes. Techniques in Biology (Ch 1 Sheeler) (12 Periods) Marks: 100 Principles of microscopy. semiautonomous nature. mitochondrial DNA Chloroplast Structure. marker enzymes. Signal peptide hypothesis. Membrane proteins and their functions. Phase contrast microscopy. N-linked glycosylation. Lysosome formation. Light Microscopy. Cell wall Unit 5. Cell as a unit of Life (Ch 6 Campbell) (10 Periods) The Cell Theory. (Ch 7 Campbell / Ch 15 Sheeler / Ch 3 Raven) (8 Periods) • • • • Unit 4. functions in animals and plants and biogenesis Nucleus: Nuclear Envelope. chloroplast DNA ER. Fluorescence microscopy. Molecular controls. Models of membrane structure. chromatin. composition. Peroxisomes and Glyoxisomes: Structures.20 Sheeler) (22 Periods) Mitochondria: Structure. Confocal microscopy. Meiosis 17 | P a g e . Cell Organelles • (Ch 15. Prokaryotic and eukaryotic cells. 16. Sample Preparation for electron microscopy. Sample Preparation for light microscopy. Selective permeability of the membranes. Cell size and shape.19. X-ray diffraction analysis Unit 2. euchromatin and heterochromatin. Cell Membrane and Cell Wall The functions of membranes. DNA packaging in eukaryotes. Cell Cycle: Interphase. Cell secretion.18. composition. molecular organization.structure of nuclear pore complex. 13 Campbell) (8 Periods) Role of Cell division. Mitosis and Meiosis (Ch 12. mitochondrial biogenesis. composition. Proteins synthesized within mitochondria. Role of golgi in Olinked glycosylation. nucleolus and ribosome structure (brief). marker enzymes. Overview of Cell cycle. Electron microscopy (EM)Scanning EM and Scanning Transmission EM (STEM). Carbohydrates in the membrane. 17. Golgi body & Lysosomes Structures and roles. Semiautonomous nature.
2. 9. 8. Preparation of temporary mounts of striated muscle fiber 6. 2. John Wiley & sons NY LSPP 202-BIOLOGY-II PRACTICALS Marks: 50 1. To prepare temporary stained preparation of mitochondria from striated muscle cells /cheek epithelial cells using vital stain Janus green. organic solvent on semi permeable membrane.A. Sheeler. P. 4. eukaryotic cells with the help of light and electron micrographs. To prepare temporary stained squash from root tips of Allium cepa and to study the various stages of mitosis. 3rd edition. Study of the photomicrographs of cell organelles 3. Raven. D. 7. Pearson Benjamin Cummings. To study the structure of plant cell through temporary mounts. Study of plasmolysis and deplasmolysis on Rhoeo leaf. Study the effect of temperature. New Delhi 3. To study prokaryotic cells (bacteria). (2008) Biology 8th edition. P and Bianchi. 11. San Francisco. (2006) Cell and Molecular Biology. To study the structure of animal cells by temporary mounts-squamous epithelial cell and nerve cell. Demonstration of dialysis of starch and simple sugar. B. Campbell. J.E. 10. Study the structure of nuclear pore complex by photograph (from Gerald Karp) 18 | P a g e . 12. and Reece.H et al (2006) Biology 7th edition Tata McGrawHill Publications. viruses.SUGGESTED BOOKS 1. N. 5. Measure the cell size (either length or breadth/diameter) by micrometry.
cold. iodine. pregnant and nursing mothers.their causes and prevention through dietary/lifestyle modifications.Paper 7-LSPT 203. Causes of food spoilage.their causes and dietary treatment. constipation. Food adulteration Nutrition through the life cycle. Vitamin A deficiency. prevention and government programmes. symptoms. Unit 3 18 Periods Nutritional Biochemistry Carbohydrates. Essential and Non-essential amino acids. Structure and properties Significance of acid value. Proteins . Lipids.smoking. NUTRITION AND HEALTH THEORY Unit 1 Basic concept of food and nutrition Marks: 100 2 Periods Unit 2 12 Periods Functions of food Components of food-nutrients (Macro and micronutrients): their biochemical role and dietary sources. Unit 5 Food hygiene Potable water. Classification. phosphorus. Enzymes.Definition and concept of health. their Structure and properties Minerals.adults. Properties.FOOD. preschool and school children. 24 Periods Major nutritional deficiency diseases. Social health problems. cough. nutrient needs and dietary pattern for various groups.Iron. Classification. drug dependence and Aquired Immuno Deficiency Syndorme (AIDS). adolescents and elderly. diabetes mellitus. treatment.Definition. Life style related diseases. alcoholism.Physiological considerations. Coenzymes Vitamins.Fat-soluble and Water-soluble vitamins. and obesity. their causes. diarrhoea. fevers.sources and methods of purification Food and Water borne infections 4 Periods 19 | P a g e . if any.Protein Energy Malnutrition. infants.hypertension.Definition. iodine value and saponification value of lipids. Food groups and the concept of a balanced diet. Iron deficiency anemia. selenium and zinc: their properties Unit 4 Health Introduction to health. Iodine deficiency disorders. Common aliments. calcium.
Biochemistry. 2007. Oxford & IBH Publishing Co. 9. 7. New Age International (P) Ltd. Fundamentals of Foods. 4. 3. Academic Excellence. 2007. 6. First Ed. Preparation of temporary mounts of various stored grain pests. 3. and Stryer. Lakra P. Rao NP. New Age International (P) Ltd. Shadaksharaswamy. L. To determine absorbed oil content in fried foods. 4. New Age International Publishers Srilakshmi B. (2006). OR Identify nutrient rich sources of foods. Handbook of Foods and Nutrition. Estimation of lactose in milk.Undertake computer aided diet analysis and nutrition counseling for different age groups. J. Tymoczko. LSPP 203.SUGGESTED BOOKS 1. M.H Freeman and Co. their seasonal availability and price. 2. Wardlaw GM. Berg. 2009. Nutrition and Diet Therapy. Blackwell Publishing. Swaminathan M. 2007. and Reddy V. MV. Ascorbic acid estimation in food by titrimetry. 7. Jain P et al. 2002. BAPPCO. Singh MD. Public Health Nutrition. NUTRITION AND HEALTH PRACTICALS 1. Mudambi. Acadamic Pratibha. J. 6. 8. 2007. Food-Facts and Principles. McGraw Hill. 1998. Pvt Ltd. Srilakshmi B. SR and Rajagopal. Perspectives in Nutrition.. To detect adulteration in a) Ghee b) Sugars c) Tea leaves and d) Turmeric 2. Seventh Ed. Food Science. study of nutrition labeling on selected foods. Project. First Ed. Fourth Ed. Gibney et al. Text Book of Human Nutrition. Marks: 50 20 | P a g e . Fifth Ed. 2004.FOOD. Hampl JS. Nutrition Science. Poshan va swasthya ke mool siddhant (Hindi). VI Edition. Bamji MS. Textbook of Nutrition and Health. Estimation of calcium in foods by titrimetry. 10. 5. 5. 11. Manay MS. L. W. New Age International (P) Ltd. 1986. 2008. Fifth Ed.
components and degrees of freedom of a system. Liquid junction potential and salt bridge. Unit 2. 21 | P a g e . Electrochemical series. Immiscibility of liquids. solvent extraction. Applications of conductance measurements: determination of degree of ionization of weak electrolyte. Partial miscibility of liquids: Critical solution temperature. Distillation of solutions. Gibbs Phase Rule and its thermodynamic derivation. ∆H and ∆S from EMF data. FeCl3-H2O and Na-K only). Azeotropes.Chemistry-3 (Solutions. criteria of phase equilibrium. deviations from Raoult’s law – non-ideal solutions. Unit 3. Types of electrodes. Nernst distribution law and its applications. pH determination using hydrogen electrode and quinhydrone electrode. Standard electrode potential. hydrolysis constant of a salt. Solutions Thermodynamics of ideal solutions: Ideal solutions and Raoult’s law. calculation of thermodynamic properties: ∆G. Transference number and its experimental determination using Hittorf and Moving boundary methods. Measurement of EMF of a cell. Unit 4. congruent and incongruent melting points (lead-silver. Potentiometric titrations qualitative treatment (acid-base and oxidation-reduction only). ionic product of water. Principle of steam distillation. Concept of EMF of a cell. Derivation of Clausius – Clapeyron equation and its importance in phase equilibria. Vapor pressure-composition and temperature-composition curves of ideal and non-ideal solutions. Electrochemistry and Functional Group Chemistry-2) THEORY Section A: Physical Chemistry-2 Marks: 100 (30 Lectures) Unit 1. Calculation of equilibrium constant from EMF data. effect of impurity on partial miscibility of liquids. Conductance. Ionic mobility. Nernst equation and its importance. Lever rule. Concentration cells with transference and without transference. Kohlrausch law of independent migration of ions. Conductometric titrations (only acid-base). Phase diagrams of one-component systems (water and sulphur) and two component systems involving eutectics. solubility and solubility products of sparingly soluble salts. Phase Equilibrium Phases. Conductance Conductivity. equivalent and molar conductivity and their variation with dilution for weak and strong electrolytes. Electrochemistry Reversible and irreversible cells. Thermodynamics of a reversible cell.Paper 9-CHPT 303.
Carboxylic acid derivatives (aliphatic): (Upto 5 carbons) Preparation: Acid chlorides. Reactions: Comparative study of nucleophilicity of acyl derivatives. Hofmann Bromamide reaction. Schotten – Baumann Reaction. Esters and Amides from acids and their inter-conversion. with HNO2. Anhydrides. Keto-enol tautomerism Reactions: Synthetic uses of ethylacetoacetate (preparation of non-hetero molecules having upto 6 carbon). Amines and Diazonium Salts Amines (Aliphatic and Aromatic): (Upto 5 carbons) Preparation: from alkyl halides. Reformatsky Reaction. Mutarotation. Perkin condensation. Active methylene compounds: Preparation : Claisen ester condensation.Section B: Organic Chemistry-3 (30 Lectures) Functional group approach for the following reactions (preparations & reactions) to be studied in context to their structure. Carboxylic acids and their derivatives Carboxylic acids (aliphatic and aromatic) Preparation: Acidic and Alkaline hydrolysis of Esters. Determination of configuration of monosaccharides. Carbohydrates: Classification.Zelinsky Reaction. bromination. sulphonation. Unit 5. Unit 7. cellobiose. Reactions: conversion to benzene. maltose. Diazonium salts: Preparation: from aromatic amines. Reactions: Hofmann Vs Saytzeff elimination. Carbylamine test. Glucose and Fructose (open chain and cyclic structure). Electrophilic substitution (case aniline): nitration. Unit 8. Structure of disacharrides (sucrose. Unit 6. ascending and descending in monosaccharides. absolute configuration of Glucose and Fructose. Gabriel’s Phthalimide synthesis. phenol. Reactions: Hell – Vohlard . and General Properties. dyes. 22 | P a g e . Hinsberg test. lactose) and polysacharrides (starch and cellulose) excluding their structure elucidation.
R. Conductance. Lt d. M. Distribution Study of the equilibrium of one of the following reactions by the distribution method: Marks: 50 23 | P a g e . 11. J. C. Electrochemistry and Functional Group Chemistry-2) PRACTICALS Section A: Physical Chemistry 1. Bahl : Advanced Organic Chemistry. G. John Wiley & Sons 10. shampoos and soaps (use dilute solutions of soaps and shampoos to prevent damage to the glass electrode) using pH-meter. Orient Longman. Treichel. & Townsend. S. W. Chand CHPP 303. R. Physical Chemistry 4th Ed. N. Peter Sykes :A Guide Book to Mechanism in Organic Chemistry. P. like aerated drinks. L. pH measurements a) Measurement of pH of different solutions. 9. T. Jerry March :Advanced organic Chemistry. Narosa (2004).Petrucci. G. Mahan. B. fruit juices.Kotz. I.: New York (1985). S. M. Arun Bahl and B. 2.Chemistry-3 (Solutions. (1985) General Chemistry 5th Ed. H. 3. R. Castellan. Boyd :Organic Chemistry. I. I & II)E. 8. John Wiley and Sons. H. Prentice Hall. T. Morrison & R.. Physical Chemistry Tata McGraw-Hill (2007). Macmillan Publishing Co. 4. Barrow. General Chemistry Cengage Learning India Pvt. 7.: New Delhi (2009). B. W. 2. 5. b) Preparation of buffer solutions: (i) Sodium acetate-acetic acid (ii) Ammonium chloride-ammonium hydroxide Measurement of the pH of buffer solutions and comparison of the values with theoretical values. Graham Solomon’s :Organic Chemistry. 6. J. Narosa (1998).SUGGESTED READINGS 1. University Chemistry 3rd Ed. Finar :Organic Chemistry (Vol. S.
(f) Preparation of methyl orange. (c) Oxidation of alcohol/aldehydes/hydrocarbons to carboxylic acid (d) Osazone from glucose/fructose (e) Amides and anilides from carboxylic acid. (a) Nitration of Nitrobenzene (b) Preparation of carboxylic acid by alkaline hydrolysis of ester/amide. Recrystallisation. determination of melting point and calculation of quantitative yields to be done. 24 | P a g e .Section B: Organic Chemistry Preparations: Mechanism of various reactions involved to be discussed.
Life cycle of Stemonitis /Physarum. 24 Prescott) (11 Periods) Discovery of bacteria. and Dengue and AIDS Unit 3. 12. transmission and management of diseases caused by bacteria and mycoplasma on plants.BIODIVERSITY-I MICROBES THEORY Unit 1. Symptoms. Economic importance.Chlorella Bacillariophyceae-Diatoms Phaeophyceae. Cell structure. Fungi and their allies (24 Periods) General characteristics. General structure.) 25 | P a g e . Basic criteria used in classification. and on animals (with special reference to: Tuberculosis and Cholera). Introduction to microbial world and to study its diversity Unit 2. Basic criteria used in classification (Fritsch. 18 Prescott) (11 Periods) Discovery. Comparison of Archaea and Eubacteria. 1945). Alexopoulos et al. Classification (including Baltimore’s). Detailed study of two diseases each on plants (with special reference to: Crown gall and Citrus canker). asexual and recombination. Viruses Marks: 100 (2 Period) (Ch 13 Tortora et al. (Ch 29. 9. Physiochemical and biological characteristics. 8. RNA virus (TMV).Nostoc Chlorophyceae. Wall-less forms (L-forms. 22. Unit 4. transmission and management of diseases caused by viruses in plants and in animals-with special reference to Mosaics and Vein clearing. Reproduction and spores. Reproduction–vegetative. Structure of DNA virus (bacteriophage T4). Symptoms. Heterokaryosis and parasexuality. (Ch 1 Webster and Weber) Myxomycetes: General characteristics.Volvox. Oncogenic virus (HIV).Chlamydomonas. Nutrition. Prokaryotes (Ch 11 Tortora et al. Mycoplasma. Replication. 17. 7. Range of thallus organization. Reproduction. 13 Sharma) (12 Periods) General characteristics. / Ch 16. Growth. Ecology and distribution.Porphyra and Gracilaria Unit 5. Wall composition. Ecology and significance (Physarum as an experimental tool). / Ch 21. Range of thallus organization and reproduction. Protoplasts and Sphaeroplasts) Nutrition. Important classes in relation to Applied Phycology listed below Cyanophyceae. Lytic and Lysogenic cycle. Ecology and distribution.Paper 10-LSPT 304. Algae (Ch 2. 23. 4. Ecology and distribution (with reference to distribution in Indian peninsula).Fucus and Kelps Rhodophyceae.
Oomycetes: General characteristics.17.) Associations of Fungi: Lichens: General account. I & II) The structure and reproduction of the Algae. Two diseases each on plants (with special reference to Rust of wheat and Early blight of potato).W.L. Sherwood. Pearson. 5 Webster and Weber) General characteristics. Ecology and significance.J. and on humans (with special reference to Candidiasis and Dermatophytes to be studied in detail). Life cycle of Rhizopus (Zygomycetes). Agaricus. 10th edition Microbiology: An Introduction. R. (1996) Introductory Mycology. Thallus organization. C. New Delhi.8. Joanne. (Ch 7. Sahoo Dinabandhu. Case. Delhi 26 | P a g e .K. Vikas Publishing House Ltd. and Blackwell.14. C. (2010). Fritsch F. 1935. Thallus organization. 7. New Delhi. Reproduction. and Weber. OP (2002) Textbook of Thallophytes. Fungi and Allied Organisms.5. PD (2005). Mycorrhizae: General account and its significance.11. Reproduction. (Ch 4. G.J. 2. (2007) Introduction to Fungi (3rd Edition) Cambridge Univ. B. John Wiley & Sons. Farming the ocean Aravali International. Narosa Publishing House. Life cycle of Albugo. Funke. (Basidiomycetes) and Alternaria (Deuteromycetes) Penicillium (Anamorphic fungi). 45 (Vol.E. Mims.19. Webster J. 8th edition (2011) McGraw Hill. Symptoms. Ecology and significance. Sharma.. 5. Tortora. Alexopoulos.20 Alexopoulos et al. 2000. Sharma. (Sharma 2005) SUGGESTED BOOKS 1. Tata McGraw Hill Publishing Co.22 Webster and Weber / Ch 1. Linda. 6. Prescott's Microbiology by Willey. U. USA. Delhi 8. Chris. Reproduction. Paress.S.W. 4.2. transmission and management of fungal diseases on plants. M.R. C. 3. Woolverton. Claviceps and its telomorphs (Ascomycetes) Puccinia. Inc.
Study of Rhizopus through temporary preparations. 9. Oedogonium. and Alternaria. Study of phaneroplasmodium from specimens or photographs. Specimens/ photographs and permanent slides of root nodules. Study of fungi through temporary preparations and permanent slides: Penicillium. Study Agaricus (through specimens and permanent slides only). Fucus. Viruses: EM/ Model of TMV. conjugation. Puccinia.LSPP 304. Nostoc. Study of mycorrhizae through photographs. spirilli). bacteriophage and HIV. 4. EM of endospore. 7.BIODIVERSITY-I MICROBES PRACTICALS Marks: 50 1. 3. and permanent slides. 8. Photographs of Actinomycetes. Study of symptoms of plants infected with rust and early blight. Polysiphonia. w. Study of algae through permanent slides: Volvox. Asexual and sexual structures through sections/ tease mounts and permanent slides. 27 | P a g e .m. 5. Study of habit and sporangia of Physarum/ Stemonitis from temporary mounts. Study of symptoms of plants infected with Albugo. Bacteria: Study of bacteria through permanent slides (cocci. 2. 6. EM of heterocyst. Study of lichens from permanent slides and specimens. binary fission. EM of bacterial cell (surface details and sectional view). bacilli. Infected specimens of any plants infected with mosaic virus and vein clearing virus.
Primates. Pseudocoelomates (Chapter 11. Life cycle of Plasmodium Unit 2. Origin and evolutionary radiation of reptiles Unit 14. 28 | P a g e . Fox & Barnes) (3 Periods) General characters of Cnidarians and polymorphism Unit 4. Campbell & Reece/ Ch. Aves: (Ch 34. Aceolomates (Chapter 10. Ruppert. Campbell & Reece/ Ch. Coelomate Deuterostomes (Chapter 28. Fox & Barnes) (3 Periods) General characters of Helminthes. Unit 8. Ruppert. Ruppert. Fox & Barnes) (3 Periods) General characters of Annelida . 22 & 24 J Z Young) (7 Periods) Early evolution of mammals. Fox & Barnes) (3 Periods) General characters and canal system in Porifera Unit 3. Barnes) (3 Periods) General characters of Nemethehelminthes. 15&17 J Z Young) (5 Periods) The origin of birds. Ruppert. Social life in insects. Pearl Formation Unit 9. Ruppert. Mammalia (Ch 34. Ruppert. Porifera (Chapter 5. 12 J Z Young) (5 Periods) Unit 13. Metamerism. Reptilia (Ch 34. Fox & Barnes) (3 Periods) General characters of Echinodermata. Fox & Barnes) (3 Periods) General characters of mollusca. 14 J Z Young) (5 Periods) Amniotes. Migration of Fishes Unit 12. Radiata (Chapter 7. Flight adaptations Unit 15. Evolution of Man. Life cycle of Taenia solium Unit 5. Pisces Osmoregulation. Mollusca (Chapter 12. Amphibia Origin of tetrapods (Ch 2 and 3. Water Vascular system in Starfish. Unit 10. Campbell & Reece/ Ch. Ruppert. Arthropoda General characters. Fox & Barnes) (4 Periods) General characters of Protozoa. Protista (Chapter 3.Paper 11-LSPT 305. Fox & Barnes) (4 Periods) Unit 7. Ruppert. J Z Young) (6 Periods) (Ch. Parasitic adaptations Unit 6. J Z Young) (2 Periods) (Ch 5.BIODIVERSITY-II ANIMALS THEORY Marks: 100 Unit 1. Coelomate Protostomes (Chapter 13. (Chapter 16. Protochordata Salient features Unit 11.
Amphioxus. gizzard. Limulus. 2. G. Function and Evolution. Temporary mounts Unstained mounts of Placoid scales. Dissections Digestive and nervous system of Cockroach. any three common birds-(Crow. Chordata 5. (1992). Hippocampus. Ruppert. Peripatus. Study of following specimens: Euglena. Uromastix. T. Dissections Afferent Branchial System of Scoliodon 7. Octopus. Vertebrates Comparative Anatomy. Icthyophis/ Uraeotyphlus. Salamander. and typhlosolar intestine. Tata McGraw Hill Publications. New Delhi. Millipede. Noctiluca. Saunders College Pub. Asterias. Centipede. Study of following specimens Balanoglossus. 29 | P a g e Marks: 50 . Biology. and Antedon. Owl). Viper. Daphnia. Fox and Barnes (2006) Invertebrate Zoology. Kardong. Chiton. V. 6th edition. Sycon. Temporary mounts Septal & pharyngeal nephridia and ovary of earthworm. Sea anemone and Ascaris(male and female). Metridium. S. Hermitcrab.D. 4. T. 3. Pristis. S. . model of Archaeopteryx. New Delhi. 5. K. Pearson Education. Labeo. H. Physalia. Aphrodite. Petromyzon. Study of Permanent Slides: Cross section of Sycon. Biology. Campbell & Reece (2005). Ltd. . USA. Taenia. 6. 4. Naja. of arm of Starfish. P. Invertebrate Zoology. Dentalium. Ascaris. B. Tata McGraw Hill Publishing Company. 2. of Earthworm passing through pharynx. Rhacophorus Draco. Barnes. A functional Evolutionary Approach 7th Edition. Thomson Books/Cole 3.SUGGESTED BOOKS 1. (2002). (2004). Squirrel and Bat. Nereis. Tubipora. and Johnson. Bipinnaria and Pluteus larva. duck. (Singapore) Pvt. Raven. LSPP 305.BIODIVERSITY-II ANIMALS PRACTICALS Non-Chordata 1. Beetle. Paramecium. Leech. R.
22 Hage and Carr) (20 Periods) Brief and relevant description of the following Wet techniques in Analytical Chemistry Spectroscopic techniques such as UV Chromatography Methods such as LC. Hypertension. 14. 21. Statistical Analysis and Interpretation (Ch-14 Daniel W. genetic basis. Morphological changes. Anthrax. Malaria) Inherited/genetic diseases (Diabetes. Clinical implications Diseases impacting on Western versus developing societies Social and economic factors of disease including role of health services and other organizations Unit 2. Typhoid.Nature/ types. HPLC and GC-MS Nuclear Magnetic Resonance Spectroscopy (NMR) Atomic Force and Scanning Electron Microscopy (AFM and SEM) Electrochemistry Molecular Modeling and Chemical Databases 30 | P a g e . Metastasis. Ch 7. Ch 2. Protozoan.) (6 Periods) Descriptive and analytical statistical methods /tools for evaluation of health of various human groups of interest Interpretation of statistical data in scientific publications Unit 3.Theories. 17. diagnosis and treatment Ageing. 18.INTRODUCTION TO MEDICAL DIAGNOSTICS THEORY Unit 1. Treatment How pathogenesis relates to symptoms. 20 Davidson. Analytical Technology (Ch-1. Poliomyelitis. Down Syndrome) Immunological diseases (Autoimmune hemolytic anemia (AHA). 14 Robbins. Hashimoto’s disease. 3 7. Viral. Systemic Lupus Erythematosus (SLE)) Cancer.W.AIDS. (22 Periods) Cause and molecular or cellular progression of key diseases • • • Infectious (Bacterial-Tuberculosis.Paper 12-LSPT 306. Biomedical basis of Disease 16 Weinberg) Marks: 100 (Ch 3.Leishmaniasis. Hepatitis. Di George’s Syndrome.
Ch-4 Stryer) (12 Periods) Outline methods used in hospital histopathology. Enumeration of RBC. Prentice Hall 6. (1974) Pathological basis of Disease. Ch-1 Brant. 3. Determination of Erythrocytic Sedimentation Rate. biochemistry. 4. Stryer L. 5. 6. 5th edn.W. Tymoczko J.E. Demonstration of Electrocardiogram or ECG 11.E. and Hall J. Saunders 5. (2007) Fundamentals of Diagnostic Radiology. WBC (TLC. Daniel W. 7.C. Blood platelet count by hemocytometer. LSPP 306. Estimation of Haemoglobin content of blood using Sahli’s haemoglobinometer. (2009) Biostatistics-A Foundation for Analysis in the Human Health.. Determination of bleeding and blood coagulation time.L. Clinical estimation of glucose. cholesterol by kits 9. John Wiley & Sons. 4.L. (2006) Textbook of Medical Physiology 11th edn. Determination of total sperm count (million/ml) and motility grading (WHO grading) from Rat 10. Berg J.: Davidson’s Principles & Practice of Medicine: A textbook for students and doctors’ 14th Edition. 8.. and Helms C. (2010) Analytical Chemistry & Quantitative Analysis. MRI. Ultrasound SUGGESTED BOOKS 1. W B Saunders Company 3. 2. DLC) using haemocytometer. CT. Freeman & Co. Hage D S and Carr J D. Introduction to medical imaging-X-ray.H.Unit 4. 12. (Students would be required to interpret the images under various pathological conditions) 31 | P a g e . Biochemistry. Lippincott Williams &Wilkins.M. Ultrasound. Echo.INTRODUCTION TO MEDICAL DIAGNOSTICS PRACTICALS Marks: 50 1. X-ray. 9th Edition. MRI. Detection of abnormal constituents in urine.ECG. W. 3rd edn. Brant W. 2. Physiological Measurements: Blood Pressure (normal & under stress) and Temperature. Robbins S. CT. Guyton A. Testing of blood glucose using glucometer /colorimeter 7.A. Macleod J. Diagnostic Methods (Ch-11 Guyton. and apply some of these in the laboratory Theoretical Knowledge. haematology and microbiology laboratories. Churchill Livingstone.
Kroll process. and P.t. SOCl2 and SO2Cl2 Section B: Physical Chemistry-3 (30 Lectures) Unit 1. Critical phenomena. atomic and ionic size. Hydrides of nitrogen (NH3. Hydrometallurgy. collision frequency. collision diameter and mean free path of 32 | P a g e . structure and properties with respect to stability of hydrides of p. General Principles of Metallurgy Chief modes of occurrence of metals based on standard electrode potentials.block elements. average and root mean square velocities (no derivation). and Alred-Rochow scales). organic and environmental chemistry. Unit 2. Oxidation states with reference to elements in unusual and rare oxidation states like carbides and nitrides). Fe. acidic/basic nature of the following compounds and their applications in industrial. Kinetic Theory of Gases Postulates of Kinetic Theory of Gases and derivation of the kinetic gas equation. Pb. States of Matter and Phase Equilibrium) THEORY Section A: Inorganic Chemistry-2 Marks: 100 (30 Lectures) Unit 1. ionization enthalpy. S. Parting process. Collision cross section. S and Cl Halides and oxohalides: PCl3. inert pair effect.Block Elements Periodicity in s. Temperature dependence of these distributions. Ni. covalent and interstitial). Ti. Concept of multicentre bonding (diborane).r. Cu. Unit 3. Andrews isotherms of CO2. s.and p. diagonal relationship and anomalous behaviour of first member of each group. Zn): electrolytic.block elements. Boyle temperature derivation not required). electronic configuration. PCl5. bonding and their important properties like oxidation/reduction. van der Waals equation of state for real gases. Allotropy in C. NH2OH) Oxoacids of P.and p. collision number. N2H4. oxidative refining. Ellingham diagrams for reduction of metal oxides using carbon as reducing agent. critical constants and their calculation from van der Waals equation. w. Causes of deviation.and p. Most probable.Block Elements Hydrides and their classification (ionic. Structure. electronegativity (Pauling.Paper 13-CHPT 404: Chemistry-4 (Chemistry of s & p block elements. N3H. van Arkel-de Boer process and Mond’s process. Maxwell Boltzmann distribution laws of molecular velocities and molecular energies (graphic representation – derivation not required) and their importance. Methods of purification of metals (Al. Deviation of real gases from ideal behaviour. Mullikan. compressibility factor. Compounds of s.
. 8. General methods for determination of order of a reaction. Narosa (1998). 6. Unit 4. pressure. D. 9. J.A. 3. Kotz.Law of constancy of interfacial angles. J. Glasses and liquid crystals. G. F.molecules. Ltd. R. D. Mahan.Petrucci. Symmetry elements.B. Half–life of a reaction. Wilkinson :Basic Inorganic Chemistry. B. (1985) General Chemistry 5th Ed. Barrow. 4. Treichel. Law of rational indices. H. R. Effect of temperature on surface tension and coefficient of viscosity of a liquid (qualitative treatment only) Unit 3. 2.: New York (1985). G. Structures of NaCl. Physical Chemistry 4th Ed. & Townsend. Atkins : Inorganic Chemistry. Narosa (2004). General Chemistry Cengage Learning India Pvt. Viscosity of gases and effect of temperature and pressure on coefficient of viscosity (qualitative treatment only).L. University Chemistry 3rd Ed. Bravais lattice types and identification of lattice planes. 7. 33 | P a g e . 5. Lee :A New Concise Inorganic Chemistry. first and second order reactions (both for equal and unequal concentrations of reactants). Effect of temperature. Miller indices. catalyst and other factors on reaction rates. Concept of activation energy and its calculation from Arrhenius equation. SUGGESTED READINGS 1. W. P. H. F. John Wiley. Defects in crystals. M. unit cells. Liquids Surface tension and its determination using stalagmometer. Shriver and P. Bragg’s law. crystal systems. Unit 2. Viscosity of a liquid and determination of coefficient of viscosity using Ostwald viscometer. Order and molecularity of a reaction. Castellan. J. Gary Wulfsberg : Inorganic Chemistry. Ltd.S. Chemical Kinetics The concept of reaction rates. Viva Books Pvt. Comparison of the two theories (qualitative treatment only). Derivation of integrated rate equations for zero. C. Macmillan Publishing Co. Physical Chemistry Tata McGraw-Hill (2007). W. E. Solids Forms of solids. Cotton & G. X–Ray diffraction by crystals. KCl and CsCl (qualitative treatment only). Laws of Crystallography . Oxford University Press. Theories of Reaction Rates: Collision theory and Activated Complex theory of bimolecular reactions.: New Delhi (2009). M.
Ni2+. 34 | P a g e Marks: 50 . Ba2+. Sr2+. Br–. Cu2+. SO42-. NO3–. F(Spot tests should be carried out wherever feasible. Cd2+.CHPP 404. I–.Chemistry-4 (Chemistry of s & p block elements. Cr3+. b) Determination of the critical solution temperature and composition of the phenol water system and study of the effect of impurities on it. Pb2+. CH3COO–. Mn2+. Al3+. Ca2+. S2O32 –. Bi3+. Ag+. BO33-. K+. Sn2+. NO3–. b) Study of the variation of viscosity of an aqueous solution with concentration of solute. Fe3+. Cl–. C2O42-. States of Matter and Phase Equilibrium) PRACTICALS Section A: Inorganic Chemistry Semi-micro qualitative analysis using H2S of mixtures not more than four ionic species (two anions and two cations and excluding insoluble salts) out of the following: Cations : NH4+. Anions : CO32– . PO43-. b) Study of the variation of surface tension of a detergent solution with concentration. Zn2+. (II) Viscosity measurement (use of organic solvents excluded) a) Determination of the relative and absolute viscosity of a liquid or dilute solution using an Ostwald’s viscometer. c) Study of the variation of mutual solubility temperature with concentration for the phenol water system and determination of the critical solubility temperature. (III) Phase equilibria a) Construction of the phase diagram of a binary system (simple eutectic) using cooling curves. S2 –. Co2+.) Section B: Physical Chemistry (I) Surface tension measurement (use of organic solvents excluded) a) Determination of the surface tension of a liquid or a dilute solution using a stalagmometer. SO32 –.
6 Russell / Ch 20 De Robertis / (20 Periods) Types of structures of RNA (mRNA. types of genetic material. Intrinsic and extrinsic pathways. Role of apoptosis in human diseases Stem Cells and Maintenance of adult tissues Unit 5. Translation (Prokaryotes and eukaryotes): features of genetic code and deciphering. Telomere shortening and Human Cancer. 15 Klug and Cummings) (Ch 5. ds-DNA. RNA polymerase. semi discontinuous RNA priming. types of DNA. initiation. Transcription (Prokaryotes and Eukaryotes): Ch 14. Hershey-Chase bacteriophage experiment. semi–conservative. Unit 3. 3 Russell / Ch 14 De Robertis) (18 Periods) DNA: Miescher to Watson and Crick. DNA structure. tRNA. Cancer (Ch 22 Russell) (7 Periods) Relationship of the cell cycle to cancer. replication of linear. aminoacyl tRNA synthetases.historic perspective. elongation and termination of RNA chains. Regulation of gene expression (Ch 19 Russell) (8 Periods) Prokaryotes:Lac operon and Tryptophan operon . Ǿ (theta) mode of replication. rRNA). Unit 2. replicating the 5´end of linear chromosome including replication enzymes.MOLECULAR BIOLOGY THEORY Unit 1. Griffith’s and Avery’s transformation experiments. Genes and Cancer.Paper 14-LSPT 407.various types. Genetic material: Marks: 100 (Ch 2. elongation and termination of polypeptides. and in Eukaryotes Unit 4. Apoptosis (Cell Death) & Cell Renewal (Ch 17 Cooper et al) (7 Periods) Mechanism of apoptosis. Chemicals and Radiations as carcinogen 35 | P a g e . Proteins involved in initiation. DNA replication (Prokaryotes and eukaryotes): bidirectional replication. Charging of tRNA. universality of genetic code and exceptions in some systems.
De Robertis. 6. Marks: 50 Study of special chromosomes (polytene & lampbrush) either by slides or photographs. Spencer. Cooper.E.P. Cell and Molecular Biology. 4. 4. 3. 2. LSPP 407.A..M. E.SUGGESTED BOOKS 1. Preparation of polytene chromosomes from dipteran larva.A Molecular Approach. (2009).. To make temporary squash preparation of grasshopper testis and study the various stages of meiosis 36 | P a g e .(2008) Lippincott Williams and Williams (Sixth Edition). W.S. Benjamin Cummings. iGenetics. 5. P. III Edition. Preparation of barr body (sex chromatin) Study DNA packaging by micrographs. Preparation of the karyotype and ideogram from given photograph of somatic metaphase chromosome. The Cell: A molecular approach. J. M. 3. Cummings.D. Hausman. Russell. Klug.MOLECULAR BIOLOGY PRACTICALS 1.R. Concepts of Genetics. R. C. (2009). (2009) ASM Press and Sinauer Associates (Fifth Edition). Benjamin Cummings. XI Edition. G. 2..
G. stem & leaf (monocot & dicot). (ii) SUGGESTED BOOKS 1. Brassicaceae. Natural. Reece) (11 Periods) Classification. Reece) (22 Periods) Structure of flower. Four systems of classification (Artificial. P. types of inflorescence. et al. legumes (Gram & Groundnut).Paper 15-LSPT 408. J. Singh. An Introduction to Plant Biology 3rd edition. characteristic features of different groups.H. timber (Teak & Pine). part used and important uses) with reference to cereals (Wheat & Rice). its application with reference to identification of Solanaceae. 4. spices (Black pepper & Fennel). 35 Campbell.H. Introduction Marks: 100 (Ch 29 Raven et al. Gymnosperms (Ch 29 Raven et al. W. Phylogenetic & Modern system). 37 | P a g e . Tata McGraw Hill Publishers. Pteridophytes (Ch 29 Raven et a. characteristic features of different groups. Asteraceae and Poaceae. Unit 5./ Ch 29. Angiosperms (i) (Ch 29 Raven et al. fatty oil (Mustard & Linseed). (2005) Biology of Plants 7th edition. Study of vegetative and reproductive structures (including anatomical details) in Marchantia & Funaria. Special reference to Bentham & Hooker’s system of classification. Adaptations to land habit. characteristic features of different groups. Freeman and Co. (2006) Biology 7th edition. Reece) (7 Periods) Different types of tissue. Study of vegetative and reproductive structures (including anatomical details) in Selaginella (with concept of heterospory and seed habit). (2004) Plant Systematics: Theory and Practice 2nd edition. / Ch 30 Campbell. Importance of Cultivated plants: Centres of origin of cultivated plants. fibres (Cotton & Jute). Bryophytes (Ch 29 Raven et al. medicinal (Rauvolfia & Digitalis) plants. family. ND 2.l) (11 Periods) Classification. Mauseth. Classification. 3. their organization into root. Apogamy and Apospory..BIODIVERSITY-III PLANTS THEORY Unit 1. H. beverages (Tea & Coffee). Economically important plants (botanical name. Concept of stele and its evolution. Jones and Barlett Publishers. Raven. Unit 4. Unit 3. Unit 2. Delhi./ Ch 30 Campbell.) (9 Periods) Classification. Raven P. (2003) Botany. Equisetum & Pteris. Study of vegetative and reproductive structures (including anatomical details) in Cycas & Pinus. et al. D. Oxford & IBH Publishing Co.
Angiosperms: Study of floral characters of the following families for their identification according to Bentham & Hooker’s system of classification: • • • • Solanaceae: Solanum / Withania Brassicaceae: Brassica / Alyssum Asteraceae: Calendula / Helianthus Poaceae: Triticum / Avena 11. Pteris: Morphology. and Dorling Kindersely Publishing.S. leaflet Male cone.M. L. Selaginella: Morphology. strobilus. 5. leaf with ligule. needle. mega. V. 6. Megasporphyll. (2009) Economic Botany: In the Tropics 3rd edition. Cycas: Morphology ( coralloid roots. sporophyll. W. 2. Equisetum: Morphology. Ovule. W.M. Mac Millan Publishers India Ltd.M.M. T. Kochhar. Study of economically important plants as mentioned in the theory syllabus: • Cereals: Wheat & rice –Study through herbarium specimens and microchemical tests. spores. stem through internode. (2005) Biology. capsule.M. Permanent slides showing fern prothallus.S.S. Pinus: Morphology (long and dwarf shoots). Permanent slides showing antheridial and archegonial heads. 6. T. stem.S. W.S. W. Permanent slide showing L. Funaria: Morphology. coralloid root and L. W. leaf. V. Morphology of male & female thallus. & T. Permanent slide showing T. W. spores (wet & dry). strobilus. microsporophyll & microspores. S. stem and L. bulbil.S.S. & Reece.5. xylem & phloem) through permanent slides only. L.M. LSPP 408. Campbell N. sporangia. Male cone. rhizoids. Permanent slides showing T. T. Inc. rhizoids.M. rachis. rachis. J.S. thallus through gemma cup. 9. peristome teeth and spores. 8. sclerenchyma. male cone. microsporophyll.and microsporangia. strobilus.S. 4. sporangiophore. protonema.S.L. W. V. V. L.A.S. W. sporophyte.M.S. 38 | P a g e . Pearson Education. gemmae.S.S. Permanent slides showing T. Marchantia: Morphology of thallus (vegetative and with gemma cup). collenchyma. W.S. 7.B. W.BIODIVERSITY-III PLANTS PRACTICALS Marks: 50 1.S. Study of plant tissues (parenchyma. W.S.M. leaf). • Legumes: Gram and peanut –Study through herbarium specimens and microchemical tests.M.M. 3. V. spores. operculum. Inc.S.
Databases in Bioinformatics Unit 3. Sequence Alignments (Ch 6. EMBL Nucleotide Sequence Database (EMBL-Bank): Introduction. Aim. (Ch 3 Ghosh and Mallick / Ch 2 Pevsner) (5 Periods) Introduction. Multiple Sequence Alignment (MSA). Biological Database Retrieval System. Sequence analysis tools. Database Retrieval Tool. Gene Expression Database. Sequence Retrieval. Unit 2. Unit 5. Percent Accepted Mutation (PAM). Unit 4. Protein Database. DNA Data Bank of Japan (DDBJ): Introduction. (Ch 8 Ghosh and Mallick / Ch 7 Pevsner) (8 Periods) Methods of Phylogeny. Software for Phylogenetic Analyses. Sequence Submission to NCBI. Scope and Research areas of Bioinformatics. Databases of PIR. Resources of PIR. Resources at DDBJ.Paper 16-LSPT 409-BIOINFORMATICS THEORY Unit 1. Consistency of Molecular Phylogenetic Prediction. Blocks of Amino Acid Substitution Matrix (BLOSUM). Sequence Submission to EMBL. MSA by CLUSTALW. Data Submission at DDBJ. Data Retrieval in PIR. Molecular Phylogeny 39 | P a g e . Swiss-Prot: Introduction and Salient Features. 8 Ghosh and Mallick / Ch 6 Pevsner) (10 Periods) Introduction. Nucleotide Database. Branches of Bioinformatics. Concept of Alignment. Scoring Matrices. Classification format of Biological Databases. 5 Pevsner) (25 Periods) National Center for Biotechnology Information (NCBI): Tools and Databases of NCBI. Basic local alignment search tool (BLAST). Biological Databases. Protein Information Resource (PIR): About PIR. Introduction to Bioinformatics Marks: 100 (Ch 1 Ghosh and Mallick / Ch 1 Pevsner) (5 Periods) Introduction. Biological Sequence Databases (Ch 4 Ghosh and Mallick / Ch 4.
Sequence retrieval from databases. (2006) Discovering Genomics. Construction of phylogenetic tree. Proteomics and Bioinformatics. M. Ghosh Z. Pevsner J.. Oxford University Press. Benjamin Cummings. 2. Nucleic acid and protein databases. Crop improvement. Microbial genome applications. 5. (2008) Bioinformatics: Principles and Applications.Unit 6. 3. 2. Quantitative structure-activity relationship (QSAR) techniques in Drug Design. Marks: 50 40 | P a g e . 3. and Bibekanand M. Sequence homology and Gene annotation. SUGGESTED BOOKS 1. J. Wiley-Blackwell. II Edition. Sequence alignment. 4. LSPP 409-BIOINFORMATICS PRACTICALS 1. Heyer L. (2009) Bioinformatics and Functional Genomics. Applications of Bioinformatics (Ch 11 Ghosh & Mallick / Ch 20 Pevsner) (7 Periods) Structural Bioinformatics in Drug Discovery. Campbell A. II Edition.
Quantum Chemistry and Spectroscopy) THEORY Section A: Inorganic Chemistry-3 Marks: 100 (30 Lectures) Unit 1. Quantum Chemistry & Spectroscopy Spectroscopy and its importance in chemistry. Unit 3. Crystal field effects for weak and strong fields. Quantization of rotational energy levels. Lanthanides and actinides: Electronic configurations. Link between spectroscopy and quantum chemistry.and intramolecular) 41 | P a g e . Effect of hydrogen bonding (inter. Unit 2. Structural and stereoisomerism in complexes with coordination numbers 4 and 6. Particle in a 1-D box (complete solution). Structural information derived from rotational spectroscopy. Fe. Electromagnetic radiation and its interaction with matter. rotational. separation of lanthanides (ion-exchange method only). Difference between atomic and molecular spectra. Selection rules. Crystal field stabilization energy (CFSE). ability to form complexes and stability of various oxidation states (Latimer diagrams) for Mn. Tetragonal distortion of octahedral geometry. Coordination Chemistry Valency Bond Theory (VBT): Inner and outer orbital complexes of Cr.Chemistry-5 (Chemistry of d-block elements. vibrational and electronic components. Factors affecting the magnitude of ∆. Transition Elements (3d series) General group trends with special reference to electronic configuration. Fe and Cu. concept of zero-point energy. Types of spectroscopy. Drawbacks of VBT. Ni and Cu (coordination numbers 4 and 6). Free particle. Structural information derived from vibrational spectra. quantization. Jahn-Teller distortion. Vibrations of polyatomic molecules. Born-Oppenheimer approximation: Separation of molecular energies into translational. Octahedra symmetry. lanthanide contraction. Co. Comparison of CFSE for Oh and Td complexes. quantum mechanical operators. Tetrahedral symmetry. IR spectra of diatomic molecules. Square planar coordination. magnetic properties. Spectrochemical series. Wave-particle duality. Crystal Field Theory Crystal field effect. IUPAC system of Nomenclature. Group frequencies. normalization of wavefunctions. Oxidation states. Rotational Motion: Schrödinger equation of a rigid rotator and brief discussion of its results (solution not required). Microwave (pure rotational) spectra of diatomic molecules. colour. Vibrational Motion: Schrödinger equation of a linear harmonic oscillator and brief discussion of its results (solution not required). variable valency.Paper 17-CHPT 505. Postulates of quantum mechanics. colour. magnetic and catalytic properties. Selection rules. Section B: Physical Chemistry-4 (30 Lectures) Unit 4. Quantization of vibrational energy levels.
chromophores. John Wiley. Narosa (2004). 9. J. J. J. 3. Quantum efficiency and reasons for high and low quantum yields. 2. CHPP 505. F. 2. Determination of the composition of the Fe3+ . Lambert-Beer’s law. Primary and secondary processes in photochemical reactions. 4. 42 | P a g e Marks: 50 .B. auxochromes. M. Estimation of the amount of nickel present in a given solution as Bis(dimethylglyoximato) nickel(II) or aluminium as oxinate in a given solution gravimetrically.L. Electronic Spectroscopy: Electronic excited states. 3. Narosa (1998). Colour and constitution. W. Cotton & G. E.: New York (1985).A. Treichel. 6. Photoelectric cells. R. 4. Photochemistry Laws of photochemistry. D. Estimation of (i) Mg2+ or (ii) Zn2+ by complexometric titrations using EDTA. University Chemistry 3rd Ed. 7. 5. (1985) General Chemistry 5th Ed. Castellan.: New Delhi (2009). 8. P. Ltd. F. Shriver and P. H.and substitution on vibrational frequencies. Gary Wulfsberg :Inorganic Chemistry.phenanthroline complex in solution by Job’s method. Viva Books Pvt. General Chemistry Cengage Learning India Pvt. Lee :A New Concise Inorganic Chemistry. Ltd. R.. SUGGESTED READINGS 1. Physical Chemistry 4th Ed. Quantum Chemistry and Spectroscopy) PRACTICALS Section A: Inorganic Chemistry 1. D. C. Estimation of total hardness of a given sample of water by complexometric titration.salicylic acid complex / Fe2+ . Physical Chemistry Tata McGraw-Hill (2007). & Townsend. G.S. Fluorescence and phosphorescence. Macmillan Publishing Co. Unit 5.Chemistry-5 (Chemistry of d-block elements. bathochromic and hypsochromic shifts. Kotz. 5. Oxford University Press. Photochemical and thermal reactions. Mahan. G. Atkins : Inorganic Chemistry.Petrucci. To draw calibration curve (absorbance at λmax vs. B. Free Electron model and its application to electronic spectra of polyenes. H. Wilkinson :Basic Inorganic Chemistry. M. W. concentration) for various concentrations of a given coloured compound and estimate the concentration of the same in a given solution. Barrow.
(c) Conductometric titrations for the following systems (i) strong acid . Section B: Physical Chemistry (I) Potentiometric measurements (a) Strong acid with strong base (b) Weak acid with strong base (c) Mohr’s salt with potassium dichromate (II) Conductometric measurements. 43 | P a g e . Determination of concentration of Na+ and K+ using Flame Photometry. lodide-persulphate reaction. (b) Study of the variation of molar conductivity of a strong electrolyte (KCl) and of a weak electrolyte (acetic acid) with concentration.strong base (III) Kinetic studies Study of the kinetics of the following reactions by integrated rate method: a.strong base (ii) weak acid . volumetrically or conductometrically b. Acid hydrolysis of methyl acetate with hydrochloric acid. (a) Determination of the cell constant.6.
Antigen Processing and Presentation: (Chapter 1. classes and function. Monoclonal antibodies Unit 10. allosteric enzymes and regulation Unit 5. Immunoglobulins: (Chapter 4. Immunodeficiency and autoimmunity 44 | P a g e . Cells and Organs of the Immune System: (Chapter 2. Kuby)(5 Periods) Historical perspective of Immunology. Carbohydrate Metabolism: (Chapter 14. Early theories of Immunology. Oxidative Phosphorylation: (Chapter 13. Lymphatic system Unit 8. Kuby)(3Periods) Basic structure. Active: Artificial and Natural Immunity Unit 7. 15. 16. Lipid Metabolism: Biosynthesis and β-oxidation of palmatic acid Unit 3. Lehninger) (8 Periods) Glycolysis. Kuby)(6 Periods) Brief introduction to Vaccines. Immune System in Health and Disease: (Chapter 19. Lehninger) (10 Periods) Introduction. Cells of the immune system. Lehninger) (4 Periods) (Chapter 18. Oxidative phosphorylation and ATP synthase Unit 6. Kuby) (7 Periods) Haematopoesis.BIOCHEMISTRY AND IMMUNOLOGY THEORY Marks: 100 Unit 1. Lehninger) (5 Periods) Electron transport chain. Kuby)(3 Periods) Unit 9. Innate. kinetics. Adjuvants and Haptens (Chapter 3. Adaptive (cell mediated and humoral) . Gluconeogenesis. Lehninger) (5 Periods) Unit 4.Passive: Artificial and Natural Immunity. Glycogen metabolism Unit 2. (Chapter 17. Antigens: Properties of antigens. Polyclonal sera. Deamination and Urea cycle. Kuby)(2 Periods) Unit 11. Protein Metabolism: Transamination. Citric acid cycle. Pentose phosphate pathway. inhibition. Organs of the Immune system: Primary and Secondary lymphoid organs.Paper 18-LSPT 510. Enzymes: (Chapter 6. Major Histocompatibility Complex: Structure and functions (Chapter 7. Kuby)(2 Periods) Endogenous pathway and exogenous pathway of antigen presentation Unit 12. mechanism of action. Overview of Immune System: (Chapter 1.
A.. P.BIOCHEMISTRY AND IMMUNOLOGY PRACTICALS 1. and Lehninger. M. Marks: 50 Color reaction to identify functional group in the given solution of carbohydrate. VI Edition.. Freeman and Company. Kuby. 4. Dissection and display of lymphoid organs. W.. 4. Mayes. IV Edition. (2006).. Study the activity of Trypsin using fresh tissue extracts. Roitt's Essential Immunology.SUGGESTED BOOKS 1. 8. 45 | P a g e . Principles of Biochemistry. A. 7. Burton. R.L. Martin. A. XI edition.. Roitt.. J.H. Blackwell Publishing LSPP 510. 3. K. Immunology. Cox. Nelson. L. Murray. T. Granner. B. J. D. Study of the action of salivary amylase at optimum condition. 2. K. J. (2006). P. D. W. 3. 2. R. 6. Delves. Ouchterlony’s double immunodiffusion method. I. 5. and Rodwell.. R.. D. Color reaction to identify functional group in the given solution of proteins. Goldsby. (2009). S. Viability and cell counting of peritoneal macrophages using trypan blue. Kindt.. XXVIII Edition. M.M. (2009). J. Lange Medical Books/McGraw-Hill. W. Harper’s Illustrated Biochemistry. V.H Freeman and Co. ABO blood group determination. A. Osborne.
2nd Edition) (4 Periods) Unit 4.3. Photosynthesis: brief history. mechanism of opening and closing of stomata. structure and development of anther. (Ch 7.20. Role of physical factors in growth of plants: response to light photomorphogenesis. response to temperature – vernalization. (Ch 7.) (2 Periods) Unit 2. 2nd Edition) (10 Periods) Unit 3. megasporogenesis. et al. gibberellins.4.10 Hopkins & Huner) (10 Periods) Unit 9. Structural organization of flower: Initiation and differentiation of floral organs. types of embryo sacs (Bhojwani & Bhatnagar Chapter-1.8. transport pathwaysxylem and phloem.H. 2. Plant water relationship: Significance of water.DEVELOPMENTAL BIOLOGY AND PHYSIOLOGY-PLANT THEORY Marks: 100 Unit 1. PSI & PSII e-transport.24. Mineral nutrition: essential elements.21 Hopkins & Huner) (11 Periods) Unit 8. water potential. (Ch 3. (Ch 18. biological clock. (Ch 2 Hopkins & Huner) (5 Periods) Unit 5. Role of growth regulators:auxin. signal transduction (overview). ion uptake and role of mycorrhiza. symptoms. physiological basis of deficiency. microsporogenesis. Brassinosteroids and Jasmonates. (Ch-22 Raven P. significance of polarity. pigments. Developmental Biology: Introduction and scope. (Bhojwani & Bhatnagar Chapter-6. ethylene. Solute transport: Transport of inorganic and organic components. pollen-pistil interaction. 9 Hopkins & Huner) (4 Periods) 46 | P a g e . 4 Hopkins & Huner) (6 Periods) Unit 6.19. soil factors affecting their availability. role of phytochrome and cryptochrome.26 Hopkins & Huner) (8 Periods) Unit 7.5. mechanism of light absorption and energy transfer. ATP synthesis C3 C4 & CAM Photorespiration. (Ch 3. micro and macronutrients.9. water absorption and transport. transpiration. Fertilization: Pollination. structure and types of ovule. photoperiodism. cytokinins. 7.Paper 19-LSPT 511.25. double fertilization. ABA.
USA 3. and Eichhorn S. John Wiley and Sons 2. Demonstrate the activity of nitrate reductase in leaf discs. 4th edn. W. 2. 4. S. Raven P. Bhojwani. Study the effect of CO2 concentration on the rate of photosynthesis. 4. mature anther (permanent slides). House Pvt. USA. Freeman Company Publishers.F.. To study the dynamics of growth. Demonstrate Hill’s reaction using crude extract of leaves. Determination of a effect of an environmental factor on the rate of transpiration by an excised twig using photometer.DEVELOPMENTAL BIOLOGY AND PHYSIOLOGY-PLANT PRACTICALS Marks: 50 1.. Structure of young anther wall. LSPP 511. Determination of stomatal index of leaf of the given plant material. (2005). 2. New Delhi 5. 11. 6. Introduction to Plant Physiology. 3. Raghavan V (2000) Developmental Biology of Flowering Plants. 10. Ltd.SUGGESTED BOOKS 1. 7th edn. microsporogenesis. 5.S. 3. Embryology of Angiosperms. Hopkins WG & Huner PA (2009) 4th edn. Study of monoscopic (Polygonium) type of embryo sac development (permanent slides/photographs). Delaying of leaf senescence by application of cytokinn.P. Dickinson WC (2000) Integrative Plant Anataomy. Determination of stomatal frequency of the leaf of given plant material.. To demonstrate bolting in any rosette plant. Study of embryo sac through electron micrographs showing egg apparatus. (1999). & Bhatnagar.H.E. 9. Vikas Pub. Study the effect of light intensity on the rate of photosynthesis. To demonstrate effect of auxin on rooting/abscission/apical dominance. 8. Harcourt Academic Press. Biology of Plants. To study the effect of ethrel application on fruit ripening. S. 5. 47 | P a g e . Evert R. Study the Avena coleoptile curvature test. 7. Springer-Verlag. List of suggested experiment that should be demonstrated in the class and these may be kept for comments in the practical examination 1. New York 4.H.
lethal Genes. (Ch 4 Pierce / Ch 7 Klug and (8 Periods) Unit 2. 9:4:3. 6 Pierce. Heredity: (Ch 3. Crossing over: concept and significance. 4 Klug and Cummings / Ch 11. Sex-determination and Sex-linked Inheritance: Cummings / Ch 4 Gardner) • • Sex determination in Human. coupling & repulsion. Ch 3. 13:3.GENETICS AND GENOMICS THEORY Marks: 100 Unit 1. cytological proof of crossing over. 5. complete & incomplete linkage. (Ch 10 Pierce. Chromosomal Aberrations: 48 | P a g e .dominance. Kappa particles in Paramecium. Ch 16 Klug and Cummings / Ch 11 Gardner) (6 Periods) Unit 4. 12:3:1.Paper 20-LSPT 512. recombination frequency. Mutations: • • Types of mutations. bridges experiment. linkage maps based on two factor crosses. Male sterility. 1:2:1. Linkage and Crossing over: (Ch 7 Pierce / Ch 5 Klug and Cummings / Ch 7 Gardner) (8 Periods) • • Linkage: concept & history. incomplete dominance. Drosophila & plants Sex linked inheritance Unit 3. Multiple allelism Pleiotropism Chromosome theory of Inheritance. effects of physical & chemical mutagens CLB method of detection of mutations (Ch 9 Pierce / Ch 8 Klug and Cummings / Ch 17 Russell) (14 Periods) Unit 5. leaf variegation in Mirabilis jalapa. 13 Russell / Ch 20 Gardner) (16 Periods) • • • • • • • • • • Brief life history of Mendel Terminologies Laws of Inheritance Modified Mandelian Ratios: 2:1.Co. 9:7. 12. Chi Square Pedigree Analysis Cytoplasmic Inheritance: Shell Coiling in Snail.
Laggards. Arabidopsis thaliana SUGGESTED BOOKS 1. Russell.J. W. 2. Gardner. Study of the following with the help of photographs: Sex chromosomes in Melandrium/ Coccinia. C. 3. Klinefelter’s). J. Inversion bridge.Ishihara’s Chart 7. Paralogs & orthologs.A Molecular Approach. Barr Bodies. Turner’s. Model organisms: Escherichia coli. D. M. Polyploidy and Aneuploidy • Structural chromosomal changes: Deletions.R. Construction of linkage map based on recombination frequency data obtained from a twopoint cross (use real life data). Snustad.S. (2009).J. Colour blindness. Comparative genomics of Chimpanzees and human. Freeman& co. 12:3:1 2. Unit 6. Mice and Humans. Functional Genomics Comparative Genomics: Homologs. Pedigree analysis of hemophilia in Queen Victoria family 6.. 49 | P a g e .. Inversions & Translocations.A. VIII editon Principles of Genetics. iGenetics. W. Synteny.A Conceptual Approach. III Edition. Multivalents. Klug.. (2009). 4. A. transcriptomics. 9:4:3. Wiley India.P. Chi square analysis of a dihybrid F2 population data 4. Drosophila melanogaster. (2008).. Concepts of Genetics. Translocation Ring (Rhoeo). Pierce. Meiosis – Allium cepa Buds 5. (2008). NY LSPP 512. B. Benjamin Cummings. Genomics: (Ch 20 Pierce / Ch 10 Russell) (8 Periods) Introductions to OMICS: Genomics. Benjamin Cummings. Gene Interactions with the help of Drosophila culture for the following dihybrid F2 segregation ratios: 9:7. H.• Numerical chromosomal changes: Euploidy. Spencer. metabolomics. Proteomics. Human Genome project. XI Edition. 13:3. Simmons. Duplications. E. P. 3. Human Genetic Syndromes (Down’s.GENETICS AND GENOMICS PRACTICALS Marks: 50 1. glycomics • • • • Structural Genomics: Sequencing Strategies. M. Cummings. Genetics.
Paper 21-CHPT 606. Synthesis of simple peptides (upto dipeptides) 50 | P a g e . K4[Fe(CN)6]. Zeiss salt and ferrocene. Role of Ca2+ in blood clotting. Unit 2. Ni and Co. Tertiary and Quaternary Structure of proteins. (MO diagram of CO can be referred to for synergic effect to IR frequencies). ninhydrin test. KMnO4.Chemistry-6 (Organometallics.acceptorbehaviour of carbon monoxide. Unit 3. Unit 2. Co. Structures of methyl lithium. using Gabriel’s phthalimide synthesis. Proteins and UV-IR Spectroscopy) THEORY Section A: Inorganic Chemistry-4 Marks: 100 (30 Lectures) Unit 1. complexation with Cu2+ ions. and Pyridine. Isoelectric point and Electrophoresis.A study of the following compounds (including preparation and important properties). EAN rule as applied to carbonyls. [Co(NH3)6]Cl3 . Determination of Primary structure of Peptides by degradation Edmann degradation (N-terminal) and C–terminal (thiohydantoin and with carboxypeptidase enzyme). Zwitter ion. K2Cr2O7. Na3[Co(NO2)6]. Amino Acids. Section B: Organic Chemistry-4 (30 Lectures) Unit 1. Role of metal ions present in biological systems with special reference to Na+. Fe. σ . Chemistry of 3d metals Oxidation states displayed by Cr. sodium nitroprusside. Role of Mg2+ ions in energy production and chlorophyll. Organometallic Compounds Definition and Classification with appropriate examples based on nature of metal-carbon bond (ionic. structure. Preparation. K+ and Mg2+ ions: Na/K pump. stabilization of protein structures and structural role (bones). Peroxo compounds of Cr. Thiophene. bonding and properties of mononuclear and polynuclear carbonyls of 3d metals. Reactions of Amino acids: ester of –COOH group.π and multicentre bonds). Synergic effects (VB approach). Pyrrole. Furan. π . Secondary. Polynuclear and Heteronuclear aromatic compounds: Properties of the following compounds with reference to electrophilic and nucleophilic substitution: Naphthalene. acetylation of –NH2 group. Peptides and Proteins: Preparation of Amino Acids: Strecker synthesis. Bio-Inorganic Chemistry A brief introduction to bio-inorganic chemistry. Overview of Primary. Bio-inorganic Chemistry. Anthracene .
aldehydes . bathochromic and hypsochromic shifts. Application of electronic spectroscopy and Woodward rules for calculating λ max of conjugated dienes and α.A. Peter Sykes: A Guide Book to Mechanism in Organic Chemistry. John R.S. J. James E. Pearson Publication.C. Application of Spectroscopy to Simple Organic Molecules Application of visible. SUGGESTED READINGS 1. carboxylic acids and derivatives (effect of substitution on >C=O stretching absorptions). 3. E. Bassler and T. Wilkinson: Basic Inorganic Chemistry.N. ultraviolet and Infrared spectroscopy in organic molecules. Separation of mixtures by chromatography: Measure the Rf value in each case. 9.by N-protection (t-butyloxycarbonyl and phthaloyl) & C-activating groups and Merrifield solidphase synthesis. Tarr: Inorganic Chemistry. Silverstein. Boyd: Organic Chemistry. Orient Longman. functional group and Finger print region. I. I & II). Arun Bahl and B.M.B. Miessler and Donald A. R. alkenes and simple alcohols (inter and intra molecular Hydrogen bonding). Bio-inorganic Chemistry. ketones. 7. (Combination of two ions to be given) Paper chromatographic separation of Fe3+. John Wiley & Sons. Dyer: Applications of Absorption Spectroscopy of OrganicCompounds. John Wiley & Sons. R.B. Prentice Hall.S.L.Chemistry-6 (Organometallics. Morrill: Spectroscopic Identification of Organic Compounds. Unit 3. L. S. Lee :A New Concise Inorganic Chemistry. Infrared radiations and types of molecular vibrations. Cotton & G. 2. G. Prentice Hall. Pearson Publication.T. Ellen Keiter and Richard Keiter: Inorganic Chemistry: Principles of Structure and Reactivity. electronic transitions .β – unsaturated compounds. 6. 5. Finar: Organic Chemistry (Vol. F. A13+ and Cr3+ or 51 | P a g e Marks: 50 .L. λmax & ε max. chromophore. 8. Bahl : Advanced Organic Chemistry. E. S. Morrison & R. Huheey. Proteins and UV-IR Spectroscopy) PRACTICALS Section A: Inorganic Chemistry 1. G. Electromagnetic radiations. auxochrome.L. 10. 4. IR spectra of alkanes.D. Chand CHPP 606.C.
phenolic. 52 | P a g e . ketonic. MgCl2 and Section B: Organic Chemistry Systematic Qualitative Organic Analysis of Organic Compounds possessing monofunctional groups (-COOH. Preparation of any two of the following complexes and measurement of their conductivity: (i) tetraamminecarbonatocobalt (III) nitrate (ii) tetraamminecopper (II) sulphate (iii) potassium trioxalatoferrate (III) trihydrate Compare the conductance of the complexes with that of M/1000 solution of LiCl3.Paper chromatographic separation of Ni2+. aldehydic. 1o amines) and preparation of one derivative. nitro. Co2+. NaCl. Mn2+ and Zn2+ 2. amide.
Gene therapy (ADA and Cystic fibrosis) and Stem Cells. Transformation techniques (microbial. Restriction and modifying enzymes. Micro-organism as food (e. Production and applications of transgenic plants (biotic. Construction and screening of DNA libraries. Filariasis. plants and animals). 10. Polymerase chain reaction and DNA microarrays. 23 Glick & Pasternak) (22 Periods) Molecular diagnosis of genetic diseases (Cystic fibrosis. amino acids. 29 Pelczar) (12Periods) Microbiology of fermented food and food-borne diseases. Food and industrial microbiology (Ch 28. 4 Glick & Pasternak) (16 Periods) Introduction to the concept of Recombinant DNA Technology. 5 Park) (10 Periods) Epidemiology of infectious disease. Recombinant DNA in medicines (Recombinant insulin and Human growth hormone). Cloning vectors. 21. Molecular analysis of DNA.e. Malaria. Bioremediation. DNA sequencing (MaxamGilbert and Sanger methods). 12. 20. prevention and control of human diseasesTuberculosis.Paper 22-LSPT 613. Major products of industrial microbiology-antibiotics. Huntington’s disease and Sickle cell anemia). 11. Ethics and regulation of GM organisms 53 | P a g e . organic acids. Recombinant vaccines. Northern and Western blotting). Amoebiasis. Ch 3. Southern. Unit 3. Agarose and Polyacrylamide Gel Electrophoresis. transmission. 19. SCP). food preservation. vitamins. Japanese encephalitis Unit 2. Applications of Biotechnology (Ch 9. Molecular Techniques in Gene manipulation (Ch 1.g.APPLIED BIOLOGY AND BIOTECHNOLOGY THEORY Unit 1. pharmaceuticals. RNA and Proteins (i. abiotic and improvement of nutritional quality) and transgenic animals (generation of medicines and hormones). Human diseases Marks: 100 (Ch3. Dengue. Unit 4.
2. coli. A. Separation of proteins by SDS-PAGE. Watson. Freeman and Co.B publishers 3. 4. Isolation of plasmid DNA from E.Genes and Genomes. K (2007) Preventive and social medicine B.Principles and applications of recombinant DNA. M. J. 3rd edition.R.. J.J. 3.M. DNA sequencing: Interpretation of sequence from the data provided. Analysis of DNA fingerprint 8. Pelczar. J. Glick. New Delhi 2.APPLIED BIOLOGY AND BIOTECHNOLOGY PRACTICALS 1. Marks: 50 54 | P a g e . 7. Ligation of Target DNA. R. ASM press.coli (pUC 18/19) and calculation of transformation efficiency. Myers. helminth parasites and arthropod vectors associated with human diseases. Restriction Endonuclease Digestion of plasmid DNA. 9. (2010) Molecular Biotechnology. Transformation of E..D. LSPP 613. 4. J. Study of protozoan. 5. (2007) Recombinant DNA. Washington. and Pasternak.A short course.SUGGESTED BOOKS 1. Gene amplification using PCR 6.. et al (2001) Microbiology 5th edition Tata McGraw-Hill Co. B. NY. Caudy. Park. Witkowski.K.
Digestion & absorption of food Structure & function of gastrointestinal tract Unit 4. Cardiovascular physiology (Ch 12 Sec A. Ch 9 Sec A (12 Periods) (Ch 15 Vander) (6 Periods) (Ch 47 Campbell) (12 Periods) Marks: 100 (Ch 1. functional role of endocrine glands. Functioning of excitable tissue (nerve & muscle) Vander) (Ch 6 Sec A. cleavage.Paper 23-LSPT 614. generation & propagation of nerve impulse. E Vander) (9 Periods) Heartbeat coordination. water balance & counter-current mechanism Unit 6. C. Cardiovascular pattern in health & disease. cell fate Unit 3. Respiration & Renal physiology (Ch 13 Vander/ Ch 44 Campbell) (12 Periods) Transport of oxygen & carbon dioxide in blood. Unit 7. Animal development Gametogenesis. gastrulation. skeletal muscle –molecular mechanism of contraction. Anatomical aspects of development biology Unit 2. 46 Campbell) (6 Periods) Common features of endocrine system. Unit 5.ANIMAL THEORY Unit 1. cardiac cycle. Endocrine system and reproduction (Ch 45. B. 55 | P a g e .DEVELOPMENTAL BIOLOGY AND PHYSIOLOGY. fertilization. 2 Gilbert) (3 Neural tissue. Functional anatomy of kidney. Principles of developmental biology Periods) History. B.
ileum. Study the reflex action in a spinal frog 5.B.DEVELOPMENTAL BIOLOGY AND PHYSIOLOGY -ANIMAL PRACTICALS Marks: 50 1.cleavage types.P.F. kidney. K. 36h. Widmaier E. Strang. thyroid. 2. 24h. 2.A.. Study of development stages of chick 18h. Inc. & Reece. Histological slides. blastula. Study of development stages of frog: . S. pituitary. gastrula.Inc. Mc Graw Hill LSPP 614. J. (2006) 8th edn. cartilage. neural tube). ovary. liver.T. 4. 28h. neurula (neural fold. duodenum. 3. 48h. testis 56 | P a g e . Sinauer Associates. 3.Vander’s Human Physiology. pancreas. rectum.Examination of sections of mammalian skin. Recording of frog’s heart beat in situ. lung. Pearson Education. (2005) 8th edn. trachea. 6. Campbell N. Gilbert. and Dorling Kindersely Publishing. oesophagus. 72h by raising chick embryo in the laboratory. (2004) 9th edn. adrenal.SUGGESTED BOOKS 1. bone. Developmental Biology. Biology. Preparation of haemin and hemochromogen crystals. external gill stage of tadpole. Inc. Raff.. H. spleen. salivary glands.
parks and biosphere reserves in India. biomes. National and Local). EIA-Environmental Impact Assessment (Global. 9 Miller) (14 Periods) Biodiversity and regional conservation strategies success stories with reference to India and sustainable utilization. Environment related concepts and laws (theory of tolerance. Community and Ecosystem Ch 20. population interactions. sex ratio. 22 Smith/ Ch 3 Miller) Marks: 100 (Ch 4 Allaby. Community characteristics. Environmental Issues. symbiosis Unit 3. age ratio. predator-prey system. 15. social parasitism. Threatened species of animals Unit 4. Population and Community Ecology (Part 4 and 5 Smith /Ch 6. Biogeochemical cycles. Unit 5. laws of limiting factors). Phytogeographic realms. 25 Smith) (10 Periods) Phytogeography. 8. Biogeography (Part 23. Concept of habitat and niche.organization and concept of habitats and niche. life history strategies. 16 Miller) (10 Periods) Impact of urbanization and industrialization. Policies and Regulation (Unit 8 Mishra/ Ch 27. Bioresource management (Unit 4 Mishra/ Ch 6 Allaby/ Ch 4. (18 Periods) Inter-relationships between living world and environment. endangered and threatened species of plants and animals in India. Unit 2. dispersal and dispersion of population. Introduction to Ecology. functional and numerical response. 21.ECOLOGY AND ENVIRONMENTAL MANAGEMENT THEORY Unit 1. Hydrologic cycle. environmental pollution. Biosphere. restoration of degraded ecosystems. bioremediation. Bioenergetics. ecosystem and its components (abiotic and biotic). natality. Principles of wildlife management. exponential and logistic growth. germplasm banks. Vegetation of India. 24. major plant communities of the world. Zoogeography: Zoogeographic realms. 7 Miller) (6 Periods) Population attributes. wildlife sanctuaries. 29 Smith/ Ch 11. global climatic change 57 | P a g e . predation-types. mortality. density.Paper 24-LSPT 615. host-parasite interactions.
(2002) Basics of Environmental Science Routledge 3. Study of the biotic and abiotic components of any one ecosystem 2. Project work .sieve method. M. Study of life tables and Survivorship curves 4.C.ECOLOGY AND ENVIRONMENTAL MANAGEMENT PRACTICALS 1. and Smith.water or air pollution Conventional sources of energy Visit to a National Park or wild life sanctuary One Ecosystem – Natural or Human modified Marks: 50 58 | P a g e .any one • • • • • Restoration of biodiversity Collection of data on. Ecological adaptations of two animals and two plants 6. Study of population density by using different methods – natural and hypothetical community 3. Measurement of soil pH. Smith. Miller.T (2006) Environmental Science 11th edition Brooks/Cole LSPP 615. soil analysis by rapid field method 5. (2005) Environmental Studies Selective and Scientific Books. Mishra. Allaby. New Delhi 2. A. temperature and texture.M. T. G. R. (2006) Elements of Ecology Ist editon Pearson Publications 4.SUGGESTED BOOKS 1.
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