NURS 1566 Clinical Form 3: Clinical Medications Worksheets (You will need to make additional copies of these forms

) Generic Name Cefazolin Classification Dose Route Time/frequency Anti-infectives, first 1gm/D5W 5 IV Q8H generation 50 ml @ 100 cephalosporins ml/hr Peak Onset Duration Normal dosage range 5 min Rapid 6-12 hr 1g within 30-60 min prior to incision (an additional 500mg-1g should be given for all surgeries ≥ 2 hr. 500mg-1g should then be given for all surgeries every 6-8 hr for 24 hr following surgery Why is your patient getting this medication For IV meds, compatibility with IV drips and/or solutions Perioperative prophylaxis for bacterial infection Trade Name Ancef

Mechanism of action and indications (Why med ordered) Binds to bacterial cell wall membrane, causing cell death. Bactericidal action against susceptible bacteria

Nursing Implications (what to focus on) Contraindications/warnings/interactions Hypersensitivity to cephalosporins, use cautiously in renal impairment Common side effects Seizures, Pseudomembranouis Colitis, Anaphalaxis, serum sickness, diarrhea, nausea, vomiting, rashes, phlebitis at IV site

Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically) None for this patient.

Nursing Process- Assessment (Pre-administration assessment) Assess for infection (vs, appearance of wound, sputum, urine, and stool; WBC) at beginning and throughout therapy. Determine if hx of cephalosporin reaction has occurred. Monitor IV site often for thrombophlebitis ( pain, redness, swelling) Change sites every 48-72 hr to prevent phlebitis. Do not use solutions that are cloudy or contain precipitate.

Lab value alterations caused by medicine May cause a positive Coomb’s test in pt. receiving high doses or in neonates whose mothers were given cephalosporins before delivery. May increase serum AST, ALT, alkaline phosphatase, bilirubin, LDH, BUN, creatinine. May cause leucopenia, neutropenia, thrombocytopenia, and eosinophilia Be sure to teach the patient the following about this medication Report s/s of superinfection (furry overgrowth on the toung, vaginal itching or discharge, loose foul-smelling stools) and allergy. Notify Dr. if fever and diarrhea develop, esp. if diarrhea contains blood, mucus, or pus. Do not treat diarrhea without consulting health care professional. Assessment Evaluation Why would you hold or not give this med? Check after giving S/S of anaphylaxis ( rash, pruritus, laryngeal Resolution of s/s of infection. edema, wheezing), D/C drug and notify Length of time for complete physician. resolution depends on the organism and site of infection. Decreased incidence of infection when used for prophylaxis

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