NURS 1566 Clinical Form 3: Clinical Medications Worksheets (You will need to make additional copies of these forms

) Generic Name Levofloxacin Peak 1-2 hours Trade Name Levaquin Onset rapid Classification Anti-infectives Duration 24 hrs Dose 250 mg Route PO Time/frequency Q day

Normal dosage range 250-750 mg q 24 hr For IV meds, compatibility with IV drips and/or solutions N/A

Why is your patient getting this medication Eurosepsis, infection

Mechanism of action and indications (Why med ordered) Inhibit bacterial DNA synthesis by inhibiting DNA gyrase. Broad spectrum for gram positive and gram negative pathogens.

Nursing Implications (what to focus on) Contraindications/warnings/interactions . Hypersensitivity, Renal impairment, Geriatric patients, Administration with antacids, iron salts, bismuth subsalicylate , sucralfate , and zinc salts decreases absorption of fluoroquinolones Common side effects dizziness, drowsiness, headache, insomnia, abdominal pain, diarrhea, nausea

Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically)

Nursing Process- Assessment (Pre-administration assessment) Assess for signs of infection

Lab value alterations caused by medicine Fluoroquinolones may cause ↑ serum AST, ALT, LDH, bilirubin, and alkaline phosphatase, May also cause ↓ WBC; ↑ or ↓ serum glucose; and glucosuria, hematuria, proteinuria, and albuminuria, Monitor prothrombin time closely in patients receiving fluoroquinolones and warfarin; may enhance the anticoagulant effects of warfarin Be sure to teach the patient the following about this medication Encourage patient to maintain a fluid intake of at least 1500-2000 ml/day to prevent crystalluria, Advise patient to notify health care professional of any personal or family history of QTc prolongation or proarrhythmic conditions such as recent hypokalemia, significant bradycardia, or recent myocardial ischemia. Patients with this history should not receive fluoroquinolones, Caution patient to use sunscreen and protective clothing to prevent phototoxicity reactions during and for 5 days after therapy. Notify health care professional if a sunburn-like reaction or skin eruption occurs, Instruct patient to consult health care professional before taking any other Rx, OTC, or herbal products, Advise patient to report signs of superinfection (furry overgrowth on the tongue, vaginal itching or discharge, loose or foul-smelling stools), Instruct patient to notify health care professional if fever and diarrhea develop, especially if stool contains blood, pus, or mucus. Advise patient not to treat diarrhea without consulting health care professional, Instruct patient to notify health care professional immediately if rash or tendon pain or inflammation occur. Therapy should be discontinued Assessment Evaluation Why would you hold or not give this med? Check after giving If there was an adverse reaction Resolution of the signs and symptoms of infection which are pain, redness, swelling, odor.