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Zosyn drug card

Zosyn drug card

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Published by: Sheri490 on Mar 03, 2009
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NURS 1566 Clinical Form 3: Clinical Medications Worksheets (You will need to make additional copies of these forms

) Generic Name Piperacillin/ tazobactam Peak End of infusion Trade Name Zosyn Onset Rapid Classification Anti-infectives Duration 4-6 hr Dose 3.375 mg Route IV Time/frequency Q 8 Hours

Normal dosage range 3.375 g q 6 hr. Renal impairment (CCr < 40 ml/min) For IV meds, compatibility with IV drips and/or solutions

Why is your patient getting this medication peritonitis

Mechanism of action and indications (Why med ordered) – Akin and skin structure infections, gynecologic infections. Communityacquired and nosocomial pneumonia caused by peperacillinresistant, beta-lactamase-producing bacteria. Piperacillin binds to bacterial cell wall membrane, causing cell death. Spectrum is extended compared with other penicillins. Taxobactam inhibits betalactamase, an enzyme that can destroy penicillins. Death of susceptible bacteria. Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically) Lasix, corticosteriods

Nursing Implications (what to focus on) Contraindications/warnings/interactions Hypersensitivity to penicillins, beta-lactams, cephalosporins, or tazobactam. Cautiously in renal impairment dosage 40 ml/min. Common side effects – seizures, pseudomembranous colitis, diarrhea, rashes, pain, phlebitis, anaphylazis, serum sickness

Nursing Process- Assessment (Pre-administration assessment) Infection, VS, appearance of wound, sputum, urine, and stool, WBC.

Lab value alterations caused by medicine – May increase BUN, creatinine, AST, ALT, serum bilirubin, alkaline phosphatase and LDH. Leukopenia and neutropenia in hepatic impairment. Be sure to teach the patient the following about this medication Report signs of superinfection (black furry tongue, vaginal itching or discharge, loose or foul-smelling stools and allergy. Call Dr. if fever or diarrhea occur especially if it contains blood, pus or musus. Assessment Evaluation Why would you hold or not give this med? Check after giving superinfection (black furry tongue, vaginal Resolution of s/s of infection. itching or discharge, loose or foul-smelling Length of time for complete stools and allergy. Anaphylaxis (rash, puritus., resolution depends on the laryngeal edema, wheezing. organism and site of infection

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