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Sulfonylurea Classof Medication

Glybuyride Diabeta Euglucon Gliclazide Diamicron DiamicronMR Glimepiride Amaryl

Biguanide

Meglitinide

Alpha Glucosidase Inhibitor

Thiazolidinediones

CombinationPills
DPP4Inhibitor
Avandamet Combination of Rosiglitazone &Metformin Avandaryl Combination of Rosiglitazone &Glimepiride

IncretinAgent
GLP 1ReceptorAgonists

Metformin Glucophage Glumetza

Repaglinide Gluconorm Nateglinide Starlix

Acarbose Glucobay

Pioglitazone Actose

Rosiglitazone Avandia

Janumet Combination ofSitagliptin andMetformin

Sitagliptin Januvia

Saxaglipton Onglyza

Exenatide Byetta (Injection)

Liraglutide Victoza (Injection)

Maximum DailyDose

Maximum 20mg/day

Diamicron Maximum 320mg/day DiamicronMR Maximum 120mg/day Diamicron OnetoTwo DiamicronMR One

Maximum 8mg/day

Glucophage Maximum 2550mg/day Glumetza Maximum 2000mg/day

Gluconorm Maximum 16mg/day Starlix Maximum 540mg/day

Maximum 300mg/day

Maximum 45mg/day

Maximum 8mg/day

Maximum 8mg/2000 mg/day

Maximum 4mg/4mg/day

Maximum 100mg/ 2000mg/ day

Maximum 100mg/day

Maximum 5mg

Maximum 20 g

Maximum 1.8mg

One

OnetoTwo Maytake8 12weeks beforeyou seeaneffect Takewithor withoutfood Sametime everyday Onceto twice/day Onceaday Twiceaday Onedosea day Onceaday Twiceaday Onceaday

Numberof dailydoses

OnetoTwo

One

OnetoFour

OnetoFour

OnetoThree

Maytakeup tosixweeks beforeyou seeaneffect Takewithor withoutfood Sametime everyday

Whentotake them

Take1530 minutesbeforea meal

Take030 minutesbefore meals

Takewith breakfastorfirst mealoftheday

Usuallytaken withmeals

030minutes beforeameal

Takewithfirstbiteof foodatmeals Startwithlowdoseand graduallyincrease

Usuallytaken withmeals

Usuallywith meals

Takewith meals

Canbetaken withorwithout food

Canbe takenwith orwithout food

Anytimewithin60 minutesBEFOREyour morningmealand eveningmeal.DoNOT takethemAFTERyour meal Yourmorningand eveningmealshouldbe atleast6hoursapart

Anytimeofday

Maycause increasedheart rate Initialdoseof 0.6mgdailyfor oneweekthen increaseto 1.2mgdailyfor oneweekthen reach1.8mgif prescribed. Donotuseif havehistoryor familyhistoryof medullarythyroid cancerorif Multiple endocrine neoplasia syndrome.

Maycausefluidretention (puffiness,swellingoffeet, shortnessofbreath) Maycause diarrhea,stomach upset Doesnotcause weightgain Notrecommended ifthereis significantkidney damage Bloating,gas&diarrhea arecommonsideeffects Doesnotcauseweight gain Doesnotcause hypoglycemiabyitself Notrecommendedifyou havegastrointestinal diseases Maycauseweightgain Notrecommendedifyouareat riskofcongestiveheartfailure Callyourdoctorifyouhaveany signsofliverdisease(nausea, vomiting,stomachpain,lackof appetite,yellowingofskinor eyes,ordarkcoloredurine) Mayincreaseyourriskofgetting pregnantifyourperiodsare irregularorifyouareonbirth controlpills.

Cautions/ Comments

Maycause hypoglycemia Maycause weightgame

Lesshypoglycemia thansome sulfonylureas Donotbreak DiamicronMR Tablet

Goodatcontrolling aftermealblood glucoselevels Ifyoudonteata mealyoudonttake themedication Maycause hypoglycemia

Maycause hypoglycemia

SeeRosiglitazone & Metformin & AmarylSections

Indicatedin combinationwith Metformin Ifyoumissa dose,takeas soonas possible. However,take only1dosea day Commonside effects stuffy/runny nose&sore throat Notassociated withweightgain

Intendedto beused with metformin ora sulfonylurea Take missed doseas soonasyou remember butdonot taketwo dosesin oneday

Whentakingwith sulfonylureatoreduce riskof hypoglycemiathe sulfonylureashouldbe decreasedwhenyou starttakingByetta. No decreaseisneeded whentakingByettawith Metformin Byettaslowsgastric emptyingsoyouwill needtotakeother medicationsseparately soasnottoalterthe rateofabsorption. Ifyoumissadosejust takeyournext scheduleddosedonot adjusttimesoramounts anddonottakeadouble dose.

UpdatedJune2011