PREDISPOSING FACTORS

PRECIPITATING FACTORS

Causative Agents Fetal Presence/ Decidual cell Idiopathic Pre-eclampsia Or Eclampsia Coagulation defects

In volume

Vasospasm

Platelet activation

Hemodynamic changes

Vasoconstriction

Endothelium injury

Production but shorter lifespan

Firbrin forms cross linked network in small blood & in Hepatic sinusoids vessels

Hemolysis

Thrombocytopenia

Blocked hepatic blood flow

Microangiopathic hemolytic anemia

Pain

Elevated AST & ALT
AL

Swelling

Odd shaped RBC

Oxygen supply

Organ perfusion Mother Fetus

HELLP Syndrome

Disseminated intravascular coagulation

Poor placental perfusion

Paradoxical Bleeding

Intrauterine growth retardation

Hypoxia