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2 STEM CELLS IN BONE MARROW

MYELOID CELLS

LYMPHOID CELLS

ERYTHROCYTES RBCs

THROMBOCYTES Platelets NK cells Can attack any target

LEUKOCYTES WBCs Memory cells Acquired Immunity GRANULOCYTES Large #s Bands--babies MONOCYTES Small #s Macrophages--RES 2nd Response

B LYMPHOCYTES Mature in bone marrow Humoral Immunity

T LYMPHOCYTES Mature in thymus Cell Mediated Immunity

Memory cells Acquired Imm PLASMA CELLS Make Antibodies IgM 1st formed IgG 2nd formed Most #s IgE Releases histamine IgA Mucosal IgD ????? Regulator T cells Effector T cells

NEUTROPHILS Segs--mature Phagocytic 1st response

BASOPHILS Release histamine and heparin in allergic response

Helper T "ON" Promotes proliferation of B Lymphs and T cytotoxic

Suppressor T "OFF" Shuts off & limits T helper and B cells

EOSINOPHILS Neutralize histamine; defend against parasites

T cytotoxic Killer cells

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