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Quiz Microbiology

Quiz Microbiology

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Quiz Microbiology
Quiz Microbiology

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Published by: MedShare on Apr 15, 2009
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10/30/2015

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1) Which of the following describes enteric bacteria?
a) Gram-positive cocci
b) Gram-negative cocci
c) Gram-positive rods
d) Gram-negative rods
e) Gram-positive spirals
2.1) What is the most prevalent Enterobacteriaceae found in central nervous system
infections?

a) Escherichia
b) Klebsiella
c) Salmonella
d) Yersinia
e) Morganella
2.2) What is the most prevalent Enterobacteriaceae found in lower respiratory tract
infections?

a) Escherichia
b) Klebsiella
c) Salmonella
d) Yersinia
e) Morganella
2.3) What is the most prevalent Enterobacteriaceae found in bloodstream infections?
a) Escherichia
b) Klebsiella
c) Salmonella
d) Yersinia
e) Morganella
2.4) What is the most prevalent Enterobacteriaceae found in gastrointestinal tract
infections?

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a) Escherichia
b) Klebsiella
c) Salmonella
d) Yersinia
e) Morganella
2.5) What is the most prevalent Enterobacteriaceae found in urinary tract infections?
a) Escherichia
b) Klebsiella
c) Salmonella
d) Yersinia
e) Morganella
3.1) Which of the following is oxidase positive?
a) E. coli
b) P. vulgaris
c) K. pneumoniae
d) Salmonella
e) Shigella
f) P. aeruginosa
3.2) Which of the following ferment lactose?
a) P. vulgaris, Salmonella, and Shigella
b) E. coli and K. pneumoniae
c) P. vulgaris and Salmonella
d) Shigella, E. coli, and P. vulgaris
e) P. aeruginosa only
3.3) Which of the following is identified in the laboratory based on production of indole?
a) E. coli
b) P. vulgaris
c) K. pneumoniae
d) Salmonella
e) Shigella
3.4) Which of the following is urease positive, produces hydrogen sulfide, and is motile?
a) E. coli
b) P. vulgaris
c) K. pneumoniae
d) Salmonella
e) Shigella
3.5) Which of the following is urease negative, produces hydrogen sulfide, and is motile?
a) E. coli
b) P. vulgaris
c) K. pneumoniae
d) Salmonella
e) Shigella
3.6) Which of the following does not produce hydrogen sulfide and is non-motile?
a) E. coli
b) P. vulgaris
c) K. pneumoniae

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d) Salmonella
e) Shigella
4) Which of the following would NOT be caused by endotoxin?
a) Activation of complement
b) Release of cytokines
c) Phagocytotic inhibition
d) Thrombocytopenia
e) Fever and leukocytosis
5.1) Which of the following is a used by bacteria such as Yersinia, Salmonella, Shigella,
enteropathogenic Escherichia, Pseudomonas,
and Chlamydia to deliver their virulence
factors into targeted eukaryotic cells, acting like a molecular syringe?
a) Endotoxin
b) Capsule
c) Type III secretion system
d) Antigenic phase variation
e) Sequestering of growth factors
5.2) In the process of sequestering of growth factors by bacteria, some bacteria produce
chelating compounds (e.g., enterobactin, aerobactin) that bind which of the following?
a) Magnesium
b) Calcium
c) Phosphate
d) Sodium
e) Iron
6.1) Which of the following is an important cause of hemorrhagic colitis (HC) and
hemolytic uremic syndrome (HUS) in the United States?
a) Enteropathogenic E. coli (EPEC)
b) Enterotoxigenic E. coli (ETEC)
c) Enterohemorrhagic E. coli (EHEC)
d) Enteroinvasive E. coli (EIEC)
e) Enteroaggregative E. coli (EAEC)
6.2) Proper cooking of beef products can help reduce the risk of what kind of infections?
a) Enteropathogenic E. coli (EPEC)
b) Enterotoxigenic E. coli (ETEC)
c) Enterohemorrhagic E. coli (EHEC)
d) Enteroinvasive E. coli (EIEC)
e) Enteroaggregative E. coli (EAEC)
6.3) Which of the following is most associated with infant diarrhea in underdeveloped
countries; watery diarrhea and vomiting, and non-bloody stools?
a) Enteropathogenic E. coli (EPEC)
b) Enterotoxigenic E. coli (ETEC)
c) Enterohemorrhagic E. coli (EHEC)
d) Enteroinvasive E. coli (EIEC)
e) Enteroaggregative E. coli (EAEC)
6.4) Which of the following is most associated with Traveler diarrhea; infant diarrhea in
developing countries; watery diarrhea, vomiting, cramps, nausea, and low-grade fever?
a) Enteropathogenic E. coli (EPEC)

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b) Enterotoxigenic E. coli (ETEC)
c) Enterohemorrhagic E. coli (EHEC)
d) Enteroinvasive E. coli (EIEC)
e) Enteroaggregative E. coli (EAEC)
6.5) Which of the following has pathogenesis mediated by cytotoxic Shiga toxins as
opposed to plasmid-mediated?
a) Enteropathogenic E. coli (EPEC)
b) Enterotoxigenic E. coli (ETEC)
c) Enterohemorrhagic E. coli (EHEC)
d) Enteroinvasive E. coli (EIEC)
e) Enteroaggregative E. coli (EAEC)
6.6) Which of the following is associated with dysentery with leukocytes in stool, similar
to shingellosis?

a) Enteropathogenic E. coli (EPEC)
b) Enterotoxigenic E. coli (ETEC)
c) Enterohemorrhagic E. coli (EHEC)
d) Enteroinvasive E. coli (EIEC)
e) Enteroaggregative E. coli (EAEC)
7.1) Which of the following toxins disrupts protein synthesis causing damage to the
intestinal epithelium, and in a small subset of patients causes damage to the glomerular
endothelial cells, resulting in renal failure?
a) Vibrio cholerae
b) EHEC
c) Shigella dysenteriae
d) ETEC
7.2) Which of the following expresses a Shiga toxin which disrupts protein synthesis,
leading to destruction of intestinal villus and decreased absorption with an increase in
fluid secretion?

a) Vibrio cholerae
b) EHEC
c) Shigella dysenteriae
d) ETEC
7.3) Which of the following produces heat-labile (LT-I and LT-II) and heat-stabile (STa
and STb) enterotoxins that stimulate hypersecretion of fluids and electrolytes?
a) Vibrio cholerae
b) EHEC
c) Shigella dysenteriae
d) ETEC
7.4) Which of the following interacts with G proteins that control adenylate cyclase,
leading to the catabolic conversion of adenosine triphosphate (ATP) to cyclic adenosine
monophosphate (cAMP), resulting in a hypersecretion of water and electrolytes?
a) Vibrio cholerae
b) EHEC
c) Shigella dysenteriae
d) ETEC

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8) What virulence factor of E. coli is associated with adhesion in the urinary and
gastrointestinal tracts and also binds to a blood group antigen?
a) Colonizing factor antigens
b) Aggregative adherence fimbriae
c) P. pili
d) Intimin
e) Ipa protein

Use the following key (a-f) to match the bacteria to the illness it causes:
a) Salmonella typhi
b) Salmonella enteritidis
c) Shigella dysenteriae
d) Yersinia enterocolitica
e) Yersinia pestis
9.1) A photographer for National Geographic returning from Thailand develops a fever
and abdominal cramps on the plane. By the time the plane lands, he suffers from bloody
diarrhea. His fever peaks at 40ºC. The doctor decides to do an endoscopy exam and
makes a diagnosis based on the hemorrhagic mucosa and ulcerations observed in the
distal colon. Which of the options is the most likely cause?
9.2) A traveler from New Mexico presents to the ER with fever, dark black skin patches,
and enlarged, painful lymph nodes in his groin. He maintains an awkward pose with
extremities extended, which he says lessens his pain. Doctors begin treatment
immediately and inquire about possible flea bites. They then call local authorities in New
Mexico and ask about similar recent incidents. Which of the options is the most likely
cause?
9.3) A woman who recently returned form a trip to South America complains of a
persistent high fever, malaise, and constipation that has lasted for over a week. She
recalls that the fever began slowly and climbed its way up to the current 41ºC. A physical
exam reveals that she has an enlarged spleen and a generally tender abdomen with red
macules. The physician asks for a stool sample to complete the diagnosis. Which of the
options is the most likely cause?
9.4) A man and his two sons just returned from a vacation on their relative’s farm. All
three arrived complaining of bloody diarrhea. The youngest son becomes well
spontaneously. The older son complains of right flank pain, while the father starts to
notice tenderness in his joints. One surgeon, worried about appendicitis in the older son,
performs the initial incision and discovers a normal appendix but an inflamed colon.
After also observing swollen mesenteric lymph nodes during surgery, he makes a
diagnosis explaining the symptoms in all 3 patients. Which of the options is the most
likely cause?
9.5) A veterinary school student complains to the doctor of diarrhea and abdominal
tenderness. He is certain these symptoms followed nausea and vomiting the day before.
He admits that he may have caused himself this misery by excessively playing with his
turtle.
9.6) Which of the following is NOT a route of transmission for Shigella dysenteriae?
a) Fingers
b) Flies
c) Farms

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d) Food
e) Feces
9.7) Which of the following can be transmitted in raw milk along with the fecal-oral
routh?

a) Salmonella typhi
b) Salmonella enteritidis
c) Shigella dysenteriae
d) Yersinia enterocolitica
e) Yersinia pestis
9.8) Which of the following is commonly transmitted by uncooked chicken?
a) Salmonella typhi
b) Salmonella enteritidis
c) Shigella dysenteriae
d) Yersinia enterocolitica
e) Yersinia pestis
10) After ingestion and passage through the stomach, salmonellae are able to invade and
replicate in the M (microfold) cells that are located in Peyer patches of the terminal
portion of the small intestine. Which of the following mediates the initial invasion into
the intestinal mucosa?
a) cAMP inducing toxin
b) Capsule
c) Spore
d) Teichoic acid
e) Type III secretion system

Match the following descriptions with the term:
a) Gastroenteritis b) Septicemia

c) Enteric fever

11.1) Gradually increasing fever 10-14 days from ingestion with nonspecific complaints
such as headache, myalgias, malaise, and anorexia.
11.2) Nausea, vomiting, and non-bloody diarrhea 6-48 hours after consumption.
11.3) From Salmonella and risk is higher in pediatric, geriatric, and AIDS patients
12) Which of the following is NOT true regarding the epidemiology of bacillary
dysentery (Shigella)?
a) Primarily a pediatric disease
b) Endemic in adult homosexual males
c) Epidemic outbreaks can occur in daycare centers and nurseries
d) Primary transmission is by people with contaminated hands
e) Spreads rapidly even in communities where sanitary standards are high
13.1) Which of the following is the natural reservoir for urban plague (Y. pestis)?
a) Cows
b) Rabbits
c) Turtles
d) Rats
e) Mosquitoes
13.2) Which of the following is NOT a natural reservoir for sylvatic plague (Y. pestis)?
a) Squirrels
b) Rabbits

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c) Livestock
d) Rats
e) Domestic cats
14) Bubonic plagues (Y. pestis) is characterized by ____ and pneumonic plague (Y.
pestis
) is characterized by ____.
a) A 7-day incubation period; A 3-day incubation period
b) A > 90% mortality rate; A >75% mortality rate
c) Pulmonary disease; A painful bubo (inflammation of the lymph nodes)
d) Aerosol spreading from person-to-person; Flea bites
e) Septicemia; Cutaneous hemorrhagic necrosis

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