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BIMM 110 Pset 3

BIMM 110 Pset 3

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Published by George Chen
BIMM 110 Problem Set #3 by George Chen
BIMM 110 Problem Set #3 by George Chen

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Published by: George Chen on Apr 19, 2009
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BIMM 110 Molecular Basis of Human Disease TA: George Chen gtchen@ucsd.

edu OH: Tu 12:30-1:30 Sierra Summit or by appointment Section: W 4:00-4:50 Center 203

Problem Set 3
Announcements: • No answers for problem sets will be posted, we will go over the problems in section • The following problems cover lectures 5 & 6 • Please complete the sample problems from Professor Zhang that are posted on WebCT. We will be going over these answers in detail. 1. Based upon what you know from class, devise a molecular mechanism that could explain how only one X chromosome is inactivated in the cells of a female embryo.

2. Turner's Syndrome is the only developmentally viable monosomal disorder. Given that Turner's Syndrome is XO, why would YO not be viable?

3. Why does the expression of the XYY genotype result in a relatively less severe phenotype in comparison to other sex chromosome disorders?

4. What is the molecular basis of XY females and XX males? How are their treatments similar?

5. Monozygotic twins can form from egg division during what three stages of early development?

6. An embryo has a mutant Y chromosome that does not express the SRY gene. Describe their genital development.
© 2009 G.Chen

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