P. 1
Analogs of GHRP6

Analogs of GHRP6

|Views: 1|Likes:
Published by Wild Card
PDF Research
PDF Research

More info:

Published by: Wild Card on Jun 15, 2013
Copyright:Attribution Non-commercial

Availability:

Read on Scribd mobile: iPhone, iPad and Android.
download as PDF, TXT or read online from Scribd
See more
See less

06/15/2013

pdf

text

original

(Click here to read our disclaimer) There are a variety of GHRP chemicals, both in natural and artificial settings

. These hormones are designed to time the growth and creation of additional tissue. In scientific study these hormones are used to determine their effects of various chemicals. Additional GHRP Releasers The GHRP series is a group of hexapeptides that is designed to mimic natural growth hormone releasers. • Basic versions of these peptides include GHRP1, GHRP2 and GHRP6. These are available in natural forms, though the artificial versions of these chemicals have slightly different properties and are not considered for bodily use. • GHRP6 has been used as a template to help create additional peptides that have tetra penta and pseudotripepide properties. • Some versions of these chemicals have been designed without the nonpeptide analogs. These have a very different structural homology and have different receptors that do not respond to the pituitary and hypothalamic glands the way the natural substances would. Much of the work that has been done to study these receptors has been done by cloning the original hormone, both to provide researchers with plenty of the chemical for rounds of experiments and to determine the best method for producing an artificial version of the hormone for potential use. However, these cloned versions do not have the same homology as the natural receptors. Analyzing the Analogs

Studying the variance of the analogs in the GHRP variants suggests the natural versions of these chemicals contain a ligand that has not yet been discovered. • The analogs for the GHRP series likely have two sites of action that will allow it to interact with both the hypothalamus and the pituitary gland as necessary. This is likely to help the growth hormones regulate somatostatin or other factors that help to address hypothalamic factures. • Any chemical versions of these hormones cannot include any opioid receptor antagonists that would allow them to interact with male or female organisms in an alternate manner. • The opioid receptor antagonists that appear in certain types of natural growth hormones can neutralize the effects or influences of chemicals like GHRP6. In a natural state this is designed to ensure regulation of hormones in a system, but in an artificial state this can negatively impact the ability to study the effects of these chemicals. Studies of GHRP6 and its impact on free fatty acids, neurotransmitters, rhGH, glucocorticoids or exogenous somaostatin are ongoing to better understand the chemical design of manufactured GHRP6. Ongoing insight on the analogs of the GHRP chemical base can allow scientists to make more precise versions of these chemicals for further study.

You're Reading a Free Preview

Download
scribd
/*********** DO NOT ALTER ANYTHING BELOW THIS LINE ! ************/ var s_code=s.t();if(s_code)document.write(s_code)//-->