Implantable Diabetes Emergency Rescue for Hypoglycemia and DKA

Each year Hypoglycemia and Diabetic Ketoacidosis (DKA) result in thousands of deaths in the US and can result in permanent neurological damage in others. The implantable Diabetes Emergency Rescue chip provides a measure of insurance that is discrete, painless, and around the clock.

This device draws inspiration from implantable defibrillators that serve as an emergency rescue for those at risk for life-threatening cardiac arrhythmias. The Diabetes Emergency Rescue chip is an implantable device that can detect aberrant glucose levels significant enough to cause unconsciousness or significantly altered mental status. Once detected, the device then releases its cargo, glucagon in the case of hypoglycemia and insulin in the case of DKA. This can help prevent permanent neurological damage and allow the user to reestablish sufficient consciousness to seek further medical assistance.

Daniel Shen - Samson Phan - Alan Asbeck

The Technology:
• The sensor senses glucose levels from the interstitial fluid • The doses of glucagon and insulin given (roughly 1mg each) are small enough in volume that the device can be about the size of a grain of rice • Implanting the device would be like getting a shot • Once the payload is delivered, the device may output an RF signal indicating that it has been used

• The amount of glucagon or insulin given can be adjusted prior to implantation to match the dosing requirements of specific users • Glucose can be part of the payload for hypoglycemia, though the chip size would be larger • Electrolytes can be included with the insulin for DKA • A device may contain a payload for hypoglycemia or DKA or it may contain payloads for both with independently controlled releases • More than one device may be implanted depending on what the user is at risk for or if the required dose is large

Daniel Shen - Samson Phan - Alan Asbeck

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