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Basic EMQs

Basic EMQs

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Published by khamosh_prince
extended match questions for mrcs
extended match questions for mrcs

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Published by: khamosh_prince on Jun 27, 2013
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Basic EMQs

Theme:Causes of disease AClostridium perfringens Bclostridium difficile CEscherichia coli DHaemophilus influenzae EStaphylococcus aureus Fstreptococcus pyogenes Gnone of the above Select the most likely causative organism for the following infections. Pelvic sepsis following abdominal hysterectomy
Clostridium perfringens

Incorrect - The correct answer is Escherichia coli Post-operative diarrhoea
clostridium difficile

Correct Urinary tract infection after catheterisation
none of the above

Incorrect - The correct answer is Escherichia coli
The most likely cause of pelvic sepsis is due to E Coli as is most intra-abdominal abscesses. Other causes of pelvic abscesses include pseudomonas spp and Mycobacterium. Again, UTIs are most commonly due to E Coli. Post-operative diarrhoea is most likely a consequence of pseudomembranous colitis due to Clostridium Dificile toxin. Predisposing factors include the use of broad spectrum antibiotics but the condition can also be transmitted.

Theme:Micro-organisms AClostridium perfringens BClostridium difficile CEscherichia coli DHaemophilus influenzae EStaphylococcus aureus FStreptococcus pyogenes GNone of the above

Mycobacterium but Staphylococcus aureus is the commonest organism. Compound contaminated wounds are most susceptible.Select the most likely causative organism for the following infections. Chronic osteomyelitis may be caused by many organisms such as Salmonella spp. Chronic osteomyelitis after implant surgery Staphylococcus aureus Correct It is important to have a good idea of what organism is likely to be responsible for a particular infection so that one can tailor the antibiotic therapy accordingly. Gas gangrene Clostridium perfringens Correct Gas gangrene is caused by Clostridium perfringens (an anaerobic Gram positive spore forming rod) that is also responsible for food poisoning. Vincent's angina is due to an acute gingivitis plus pharyngeal infection and caused by Borrelia vincentii. Ludwig's angina Streptococcus pyogenes Correct Ludwig's angina is a cellulitic like infection of the floor of the mouth with the gram positive organism. Vincent's angina None of the above Correct Airway obstruction is a serious sequelae. Theme:Antibiotics . strep pyogenes.

It is used with caution in renal impairment and close monitoring of levels are required. leading to suppression of initiation of chain formation in RNA synthesis. Polymyxins Incorrect . Aminoglycosides Incorrect . It contains both amoxicillin plus clavulanic acid. but considerably higher concentration of the drug are required than for the inhibition of bacterial enzyme. . This is effective against both aerobic and anaerobic bacteria. Rifampicin is bactericidal for both intracellular and extracellular microorganisms.The correct answer is Rifampicin Rifampicin inhibits DNA-dependent RNA polymerase of mycobacteria by forming a stable drug-enzyme complex.AAminoglycosides BCiprofloxacin CCo-amoxiclav DFusidic acid EPolymyxins FRifampicin GSulphonamides HTetracyclines Select the antibiotic from the above list to which the following pertains: This agent acts as an inhibitor of nucleic aid synthesis in bacteria.The correct answer is Co-amoxiclav Co-amoxiclav is an effective broad spectrum penicillin against both Gram positives and Gram negatives. Rifampicin can inhibit RNA synthesis in mammalian mitochondria. Aminoglycosides Correct Aminoglycosides such as gentamicin are notorious for their renal toxicity and peak and trough concentrations should be measured to avoid toxicity.

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